Oleuropein and hydroxytyrosol-rich olive leaf extracts possessed hypolipidemic and hepatoprotective effects against HFD-induced metabolic disorders.

PMID:  Biomed Res Int. 2020 ;2020:1315202. Epub 2020 Jan 8. PMID: 31998777 Abstract Title:  Comparative Study on Beneficial Effects of Hydroxytyrosol- and Oleuropein-Rich Olive Leaf Extracts on High-Fat Diet-Induced Lipid Metabolism Disturbance and Liver Injury in Rats. Abstract:  Oleuropein and hydroxytyrosol, as major compounds of olive leaves, have been reported to exert numerous pharmacological properties, …

Hydroxytyrosol stimulates neurogenesis in aged dentate gyrus by enhancing stem and progenitor cell proliferation and neuron survival.

PMID:  FASEB J. 2020 Feb 6. Epub 2020 Feb 6. PMID: 32027412 Abstract Title:  Hydroxytyrosol stimulates neurogenesis in aged dentate gyrus by enhancing stem and progenitor cell proliferation and neuron survival. Abstract:  The dentate gyrus of the hippocampus is one of two brain areas generating throughout life new neurons, which contribute to the formation of …

Hydroxytyrosol and potential uses in cardiovascular diseases, cancer, and AIDS.

PMID:  Front Nutr. 2014 ;1:18. Epub 2014 Oct 27. PMID: 25988120 Abstract Title:  Hydroxytyrosol and potential uses in cardiovascular diseases, cancer, and AIDS. Abstract:  Hydroxytyrosol is one of the main phenolic components of olive oil. It is present in the fruit and leaf of the olive (Olea europaea L.). During the past decades, it has …

Antimicrobial activity of red wine and oenological extracts against periodontal pathogens in a validated oral biofilm model.

PMID:  BMC Complement Altern Med. 2019 Jun 21 ;19(1):145. Epub 2019 Jun 21. PMID: 31226983 Abstract Title:  Antimicrobial activity of red wine and oenological extracts against periodontal pathogens in a validated oral biofilm model. Abstract:  BACKGROUND: Previous research findings support an antimicrobial effect of polyphenols against a variety of pathogens, but there is no evidence …

Protective effects of grape seed proanthocyanidins against iron overload-induced renal oxidative damage in rats.

PMID:  J Trace Elem Med Biol. 2020 Jan ;57:126407. Epub 2019 Sep 18. PMID: 31570250 Abstract Title:  Protective effects of grape seed proanthocyanidins against iron overload-induced renal oxidative damage in rats. Abstract:  BACKGROUND: Excessive exposure to iron can cause kidney damage, and chelating drugs such as deferoxamine and deferiprone have limited usefulness in treating iron …

Red grape juice protects the rat thyroid gland against hypercholesterolemic changes.

PMID:  Rom J Morphol Embryol. 2019 ;60(3):921-929. PMID: 31912105 Abstract Title:  Red grape juice protects the rat thyroid gland against hypercholesterolemic changes. Ultrastructural and biochemical evidences. Abstract:  OBJECTIVES: This study aimed to assess the impact of high cholesterol diet (HCD)-induced hypercholesterolemia on the rat thyroid gland and investigate the role of grape juice (GJ) in …

Polyphenols from food and natural products: neuroprotection and safety.

PMID:  Antioxidants (Basel). 2020 Jan 10 ;9(1). Epub 2020 Jan 10. PMID: 31936711 Abstract Title:  Polyphenols from Food and Natural Products: Neuroprotection and Safety. Abstract:  Polyphenols are naturally occurring micronutrients that are present in many food sources. Besides being potent antioxidants, these molecules may also possess anti-inflammatory properties. Many studies have highlighted their potential role …

Methanol extract of Lonicera caerulea fruit has anti-motility and anti-biofilm activity against enteropathogenic Escherichia coli.

PMID:  Drug Discov Ther. 2019 ;13(6):335-342. PMID: 31956232 Abstract Title:  Methanol extract of Lonicera caerulea var. emphyllocalyx fruit has anti-motility and anti-biofilm activity against enteropathogenic Escherichia coli. Abstract:  Foodborne diseases have become a worldwide problem that threatens public health and welfare. Enteropathogenic Escherichia coli (EPEC) is one of major pathogens of moderate to severe diarrhea. …

Beta-elemene synergizes with gefitinib to inhibit stem-like phenotypes and progression of lung cancer.

PMID:  Front Pharmacol. 2018 ;9:1413. Epub 2018 Nov 30. PMID: 30555330 Abstract Title:  β-Elemene Synergizes With Gefitinib to Inhibit Stem-Like Phenotypes and Progression of Lung Cancer via Down-Regulating EZH2. Abstract:  The inhibitors for EGF receptor tyrosine kinase (EGFR-TKIs) such as gefitinib have been used as a standard treatment for non-small cell lung cancer (NSCLC), but …

A review of the molecular targets of β-elemene.

PMID:  Biomed Pharmacother. 2019 Jun ;114:108812. Epub 2019 Apr 6. PMID: 30965237 Abstract Title:  Molecular targets ofβ-elemene, a herbal extract used in traditional Chinese medicine, and its potential role in cancer therapy: A review. Abstract:  β-Elemene is a sesquiterpene compound extracted from the herb Curcuma Rhizoma and is used in traditional Chinese medicine (TCM) to …

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