Berberine can suppress the proliferation of liver cancer cells by reducing SLC1A5 expression.

PMID:  Onco Targets Ther. 2019 ;12:11751-11763. Epub 2019 Dec 31. PMID: 32021249 Abstract Title:  Berberine Inhibits Growth of Liver Cancer Cells by Suppressing Glutamine Uptake. Abstract:  Introduction: Glutamine metabolism is essential for the proliferation of cancer cells. Transported by SLC1A5, a Nadependent transporter, glutamine is absorbed for further use. Recent studies have revealed the anti-tumor …

Effect of berberine on spleen transcriptome and gut microbiota composition in experimental autoimmune uveitis.

PMID:  Int Immunopharmacol. 2020 Feb 7 ;81:106270. Epub 2020 Feb 7. PMID: 32044663 Abstract Title:  Effect of berberine on spleen transcriptome and gut microbiota composition in experimental autoimmune uveitis. Abstract:  BACKGROUND: Berberine (BBR) was reported to have immunoregulatory and anti-inflammatory properties. In this study, we investigated whether BBR could exert its effects on the development …

Wogonin inhibits cell cycle progression by activating the glycogen synthase kinase-3 beta in hepatocellular carcinoma.

PMID:  Phytomedicine. 2020 Jan 18 ;68:153174. Epub 2020 Jan 18. PMID: 31991293 Abstract Title:  Wogonin inhibits cell cycle progression by activating the glycogen synthase kinase-3 beta in hepatocellular carcinoma. Abstract:  BACKGROUND: Wogonin has been reported to exhibit various biological activities such as anti-inflammation, anti-microbial, and anti-tumor. Previous studies have demonstrated that wogonin could down-regulate Cyclin …

Chrysin administration protects against oxidative damage in varicocele-induced adult rats.

PMID:  Oxid Med Cell Longev. 2017 ;2017:2172981. Epub 2017 Dec 19. PMID: 29410731 Abstract Title:  Chrysin Administration Protects against Oxidative Damage in Varicocele-Induced Adult Rats. Abstract:  Oxidative stress is known as the leading factor responsible for varicocele-related infertility and for that reason, many antioxidant therapies have been proposed. Considering that, we evaluated the reproductive outcomes …

Neuroprotective effects of chrysin on diclofenac-induced apoptosis in SH-SY5Y cells.

PMID:  Neurochem Res. 2020 Feb 10. Epub 2020 Feb 10. PMID: 32040722 Abstract Title:  Neuroprotective Effects of Chrysin on Diclofenac-Induced Apoptosis in SH-SY5Y Cells. Abstract:  Accumulating evidences demonstrated that Reactive Oxygen Species (ROS) may lead to serious damages to numerous cellular biomolecules, consequently resulting in the development of several neurological diseases. Diclofenac (Dic), the most …

Ginsenosides reduce body weight and ameliorate hepatic steatosis in high fat diet‑induced obese mice.

PMID:  Mol Med Rep. 2020 Jan 13. Epub 2020 Jan 13. PMID: 32016448 Abstract Title:  Ginsenosides reduce body weight and ameliorate hepatic steatosis in high fat diet‑induced obese mice via endoplasmic reticulum stress and p‑STAT3/STAT3 signaling. Abstract:  Obesity has been increasing globally for over three decades. According to previous studies, dietary obesity is usually associated …

Ginsenosides induce extensive changes in gene expression and inhibit oxidative stress-induced apoptosis in human lens epithelial cells.

PMID:  BMC Complement Med Ther. 2020 Feb 11 ;20(1):44. Epub 2020 Feb 11. PMID: 32046688 Abstract Title:  Ginsenosides induce extensive changes in gene expression and inhibit oxidative stress-induced apoptosis in human lens epithelial cells. Abstract:  BACKGROUND: The effect of ginsenosides on the growth and apoptosis of human lens epithelial (HLE) B3 cells exposed to HOwas …

Catechins inhibit transmissible gastroenteritis virus (coronavirus) proliferation in vitro and mitigates reactive oxygen species conditions induced by its infection.

PMID:  Res Vet Sci. 2015 Dec ;103:28-33. Epub 2015 Sep 12. PMID: 26679792 Abstract Title:  (+)-Catechin inhibition of transmissible gastroenteritis coronavirus in swine testicular cells is involved its antioxidation. Abstract:  Transmissible gastroenteritis virus (TGEV) causes transmissible gastroenteritis (TGE), especially in newborn piglets, which severely threatens the worldwide pig industry. In this study, (+)-catechin was evaluated …

H. cordata has much potential for the development of antiviral agents against coronavirus and dengue infections.

PMID:  Asian Pac J Trop Med. 2016 Jan ;9(1):1-7. Epub 2015 Dec 19. PMID: 26851778 Abstract Title:  Evaluation of antiviral activities of Houttuynia cordata Thunb. extract, quercetin, quercetrin and cinanserin on murine coronavirus and dengue virus infection. Abstract:  OBJECTIVE: To evaluate the in vitro activities of the ethyl acetate (EA) fraction of Houttuynia cordata (H. cordata) Thunb. …

Probiotics and flaxseed administered together improve the condition of piglets with confirmed presence of E. coli and coronavirus.

PMID:  Anim Sci J. 2016 Sep ;87(9):1157-66. Epub 2015 Dec 21. PMID: 27581561 Abstract Title:  Synbiotics suppress the release of lactate dehydrogenase, promote non-specific immunity and integrity of jejunum mucosa in piglets. Abstract:  The aim of our experiment was to study how synbiotics are able to deal with the problems of post-weaning piglets. Lactobacillus plantarum …

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