PMID: J Pharm Pharmacol. 2017 Feb ;69(2):109-122. Epub 2016 Dec 1. PMID: 27905101 Abstract Title: A review on antiviral activity of the Himalayan medicinal plants traditionally used to treat bronchitis and related symptoms. Abstract: OBJECTIVES: Bronchitis is a common respiratory tract infection of humans mainly caused by influenza virus, rhinovirus, adenovirus, coronavirus and respiratory syncytial …
Author Archives: Taylor Mercado
Sesquiterpenoids from the flowers of Chrysanthemum indicum protect against the cytotoxic effect of porcine epidemic diarrhea virus (coronaviridiae) and reduce nucleocapsid and spike protein synthesis.
PMID: J Nat Prod. 2017 02 24 ;80(2):298-307. Epub 2017 Feb 3. PMID: 28156114 Abstract Title: Sesquiterpenoids with Various Carbocyclic Skeletons from the Flowers of Chrysanthemum indicum. Abstract: A phytochemical investigation of the flowers of Chrysanthemum indicum yielded sesquiterpenoids 1-25 with various carbocyclic skeletons, including 10 new (1-10) and 15 known (11-25) analogues. The structures …
Glycyrrhizin inhibits porcine epidemic diarrhea virus infection (coronaviridiae) and attenuates the proinflammatory responses by inhibition of high mobility group box-1 protein.
PMID: Arch Virol. 2017 Jun ;162(6):1467-1476. Epub 2017 Feb 7. PMID: 28175983 Abstract Title: Glycyrrhizin inhibits porcine epidemic diarrhea virus infection and attenuates the proinflammatory responses by inhibition of high mobility group box-1 protein. Abstract: Porcine epidemic diarrhea (PED), caused by porcine epidemic diarrhea virus (PEDV) infection, leads to significant economic losses in the swine …
N-Acetylcysteine supplementation alleviates intestinal injury in piglets infected by porcine epidemic diarrhea virus (a coronavirus infection).
PMID: Amino Acids. 2017 Dec ;49(12):1931-1943. Epub 2017 Mar 3. PMID: 28258325 Abstract Title: N-Acetylcysteine supplementation alleviates intestinal injury in piglets infected by porcine epidemic diarrhea virus. Abstract: Porcine epidemic diarrhea virus (PEDV) infects the intestine of young pigs, but effective measures for prevention and treatment are lacking. N-Acetylcysteine (NAC) has been shown to reduce …
Effect of Carica papaya extract toward incised wound healing process in mice clinically and histologically.
PMID: Evid Based Complement Alternat Med. 2019 ;2019:8306519. Epub 2019 Nov 19. PMID: 31827564 Abstract Title: Effect ofExtract toward Incised Wound Healing Process in Mice () Clinically and Histologically. Abstract: Wound healing entails a sequence of complex biological processes, which is a protective function of the body that focuses on a quick recovery. Reducing wound …
Japanese horse chestnuts display antiviral activity against porcine epidemic diarrhea virus of the coronaviridiae family.
PMID: Bioorg Med Chem Lett. 2017 07 1 ;27(13):3019-3025. Epub 2017 May 8. PMID: 28527823 Abstract Title: Antiviral escin derivatives from the seeds of Aesculus turbinata Blume (Japanese horse chestnut). Abstract: Porcine epidemic diarrhea virus (PEDV) causes severe diarrhea and high fatality of piglets, influencing the swine industry. Japanese horse chestnut (seed of Aesculus turbinata) …
Astragalus polysaccharides inhibit avian infectious bronchitis virus infection (coronaviridiae) by regulating viral replication.
PMID: Microb Pathog. 2018 Jan ;114:124-128. Epub 2017 Nov 21. PMID: 29170045 Abstract Title: Astragalus polysaccharides inhibit avian infectious bronchitis virus infection by regulating viral replication. Abstract: The avian coronavirus causes infectious bronchitis (IB), which is one of the most serious diseases affecting the avian industry worldwide. However, there are no effective strategies for controlling …
The protective effect of Lonicera japonica polysaccharide on mice with depression by inhibiting NLRP3 inflammasome.
PMID: Ann Transl Med. 2019 Dec ;7(24):811. PMID: 32042827 Abstract Title: The protective effect ofpolysaccharide on mice with depression by inhibiting NLRP3 inflammasome. Abstract: Background: Depression is associated with the abnormal activation of the human inflammatory response system, which is a life-threatening disorder affecting millions of people of all ages around the world. The purposes …
Antibody titers against Newcastle Disease and infectious bronchitis virus (a coronaviridiae virus) were higher in chickens fed Flammulina velutipes mushrooms compared to chickens receiving antibiotics.
PMID: J Sci Food Agric. 2019 Jan 30 ;99(2):703-710. Epub 2018 Aug 13. PMID: 29971802 Abstract Title: Dietary inclusion of mushroom (Flammulina velutipes) stem waste on growth performance and immune responses in growing layer hens. Abstract: BACKGROUND: Medicinal mushrooms contain biologically active substances that can be used as an immune-modulating agent in poultry. The present …
microRNA-222 attenuates mitochondrial dysfunction during transmissible gastroenteritis coronavirus infection.
PMID: Bioorg Med Chem. 2019 05 15 ;27(10):1981-1989. Epub 2019 Mar 26. PMID: 30940566 Abstract Title: Identification and design of novel small molecule inhibitors against MERS-CoV papain-like protease via high-throughput screening and molecular modeling. Abstract: The development of new therapeutic agents against the coronavirus causing Middle East Respiratory Syndrome (MERS) is a continuing imperative. The …
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