PMID: J Virol. 2019 Jun 15 ;93(12). Epub 2019 May 29. PMID: 30918074 Abstract Title: High-Throughput Screening and Identification of Potent Broad-Spectrum Inhibitors of Coronaviruses. Abstract: Coronaviruses (CoVs) act as cross-species viruses and have the potential to spread rapidly into new host species and cause epidemic diseases. Despite the severe public health threat of severe …
Author Archives: Taylor Mercado
Honokiol ameliorates high-fat-diet-induced obesity of different sexes of mice by modulating the composition of the gut microbiota.
PMID: Front Immunol. 2019 ;10:2800. Epub 2019 Dec 11. PMID: 31921106 Abstract Title: Honokiol Ameliorates High-Fat-Diet-Induced Obesity of Different Sexes of Mice by Modulating the Composition of the Gut Microbiota. Abstract: Accumulating data support the fact that the gut microbiota plays an important role in the progression of obesity and its related metabolic disease. Sex-related …
Many plant extracts exhibit antiviral activity against coronaviridiae.
PMID: BMC Vet Res. 2019 May 29 ;15(1):178. Epub 2019 May 29. PMID: 31142304 Abstract Title: In vitro antiviral activity of fifteen plant extracts against avian infectious bronchitis virus. Abstract: BACKGROUND: Avian infectious bronchitis (IB) is a disease that can result in huge economic losses in the poultry industry. The high level of mutations of …
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Honokiol ameliorates pulmonary fibrosis.
PMID: Toxicol Appl Pharmacol. 2020 Feb 4:114913. Epub 2020 Feb 4. PMID: 32032644 Abstract Title: Honokiol: A polyphenol neolignan ameliorates pulmonary fibrosis by inhibiting TGF-β/Smad signaling, matrix proteins and IL-6/CD44/STAT3 axis both in vitro and in vivo. Abstract: Pulmonary fibrosis (PF) is an epithelial/fibroblastic crosstalk disorder of the lungs with highly complex etiopathogenesis. Limited treatment …
Flavonoids inhibit the protease of MERS-coronavirus.
PMID: Chem Biol Drug Des. 2019 Dec ;94(6):2023-2030. Epub 2019 Sep 12. PMID: 31436895 Abstract Title: Characteristics of flavonoids as potent MERS-CoV 3C-like protease inhibitors. Abstract: Middle East respiratory syndrome-coronavirus (MERS-CoV) is a zoonotic virus transmitted between animals and human beings. It causes MERS with high mortality rate. However, no vaccine or specific treatment is …
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Zinc supplementation promotes resolution of coronavirus-related diarrhea in calves.
PMID: PLoS One. 2019 ;14(7):e0219321. Epub 2019 Jul 10. PMID: 31291305 Abstract Title: Effectiveness of zinc supplementation on diarrhea and average daily gain in pre-weaned dairy calves: A double-blind, block-randomized, placebo-controlled clinical trial. Abstract: The objective of this clinical trial was to evaluate the effectiveness of zinc supplementation on diarrhea and average daily weight gain …
A species of elderberry demonstrated antiviral activity against human coronavirus.
PMID: Virus Res. 2019 Nov ;273:197767. Epub 2019 Sep 24. PMID: 31560964 Abstract Title: Antiviral activity of Sambucus FormosanaNakai ethanol extract and related phenolic acid constituents against human coronavirus NL63. Abstract: Human coronavirus NL63 (HCoV-NL63), one of the main circulating HCoVs worldwide, causes respiratory tract illnesses like runny nose, cough, bronchiolitis and pneumonia. Recently, a …
Chinese traditional medicine, such ShuFengJieDu Capsules and Lianhuaqingwen Capsule, could be the drug treatment options for 2019-nCoV.
PMID: Biosci Trends. 2020 01 28. Epub 2020 Jan 28. PMID: 31996494 Abstract Title: Drug treatment options for the 2019-new coronavirus (2019-nCoV). Abstract: As of January 22, 2020, a total of 571 cases of the 2019-new coronavirus (2019-nCoV) have been reported in 25 provinces (districts and cities) in China. At present, there is no vaccine …
This guideline includes the guideline methodology, epidemiological characteristics, disease screening and population prevention, diagnosis, and treatment and control (including traditional Chinese Medicine).
PMID: Mil Med Res. 2020 Feb 6 ;7(1):4. Epub 2020 Feb 6. PMID: 32029004 Abstract Title: A rapid advice guideline for the diagnosis and treatment of 2019 novel coronavirus (2019-nCoV) infected pneumonia (standard version). Abstract: In December 2019, a new type viral pneumonia cases occurred in Wuhan, Hubei Province; and then named"2019 novel coronavirus (2019-nCoV)"by …
This review outlines Traditional Chinese Medicine treatments for coronavirus infections.
PMID: World J Pediatr. 2020 Feb 7. Epub 2020 Feb 7. PMID: 32034659 Abstract Title: Diagnosis, treatment, and prevention of 2019 novel coronavirus infection in children: experts' consensus statement. Abstract: Since the outbreak of 2019 novel coronavirus infection (2019-nCoV) in Wuhan City, China, by January 30, 2020, a total of 9692 confirmed cases and 15,238 …
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