PMID: J Trace Elem Med Biol. 2019 Mar ;52:37-47. Epub 2018 Nov 14. PMID: 30732897 Abstract Title: The relationship between mercury exposure and epigenetic alterations regarding human health, risk assessment and diagnostic strategies. Abstract: BACKGROUND: Exposure to the environmental toxicants poses a serious threat to human health. The extent of exposure and the development of …
Author Archives: Taylor Mercado
Mercury exposure likely contributes to the pathogenesis of autoimmunity.
PMID: Biochim Biophys Acta Gen Subj. 2019 Dec ;1863(12):129299. Epub 2019 Feb 10. PMID: 30742953 Abstract Title: Mercury-induced inflammation and autoimmunity. Abstract: BACKGROUND: Human exposure to mercury leads to a variety of pathologies involving numerous organ systems including the immune system. A paucity of epidemiological studies and suitable diagnostic criteria, however, has hampered collection of …
Continue reading “Mercury exposure likely contributes to the pathogenesis of autoimmunity.”
Developmental exposure to mercury chloride impairs social behavior in male offspring.
PMID: Toxicol Appl Pharmacol. 2019 May 1 ;370:1-13. Epub 2019 Mar 9. PMID: 30862457 Abstract Title: Developmental exposure to mercury chloride impairs social behavior in male offspring dependent on genetic background and maternal autoimmune environment. Abstract: To date, the connection between inorganic mercury (Hg) and social behavior remains incompletely understood. The aim of this study …
Mercury-induced autoimmunity: Drifting from micro to macro concerns on autoimmune disorders.
PMID: Clin Immunol. 2020 Feb 4:108352. Epub 2020 Feb 4. PMID: 32032765 Abstract Title: Mercury-induced autoimmunity: Drifting from micro to macro concerns on autoimmune disorders. Abstract: Mercury (Hg) is widely recognized as a neurotoxic metal, besides it can also act as a proinflammatory agent and immunostimulant, depending on individual exposure and susceptibility. Mercury exposure may …
The potential of flavonoids for the treatment of neurodegenerative diseases.
PMID: Int J Mol Sci. 2019 Jun 22 ;20(12). Epub 2019 Jun 22. PMID: 31234550 Abstract Title: The Potential of Flavonoids for the Treatment of Neurodegenerative Diseases. Abstract: Neurodegenerative diseases, including Alzheimer's disease (AD), Parkinson's disease (PD), Huntington's disease (HD), and amyotrophic lateral sclerosis (ALS), currently affect more than 6 million people in the United …
Continue reading “The potential of flavonoids for the treatment of neurodegenerative diseases.”
Catechin relieves hypoxia/reoxygenation‐induced myocardial cell apoptosis via down‐regulating lncRNA MIAT
PMID: J Cell Mol Med. 2020 Jan 19. Epub 2020 Jan 19. PMID: 31955523 Abstract Title: Catechin relieves hypoxia/reoxygenation-induced myocardial cell apoptosis via down-regulating lncRNA MIAT. Abstract: BACKGROUND: Catechin protects heart from myocardial ischaemia/reperfusion (MI/R) injury. However, whether catechin inhibits H/R-induced myocardial cell apoptosis is largely unknown.OBJECTIVE: This study aims to investigate the underlying mechanism …
Synergistic effects of sulfated polysaccharides from Mexican seaweeds against measles virus.
PMID: Biomed Res Int. 2016 ;2016:8502123. Epub 2016 Jun 22. PMID: 27419139 Abstract Title: Synergistic Effects of Sulfated Polysaccharides from Mexican Seaweeds against Measles Virus. Abstract: Sulfated polysaccharides (SPs) extracted from five seaweed samples collected or cultivated in Mexico (Macrocystis pyrifera, Eisenia arborea, Pelvetia compressa, Ulva intestinalis, and Solieria filiformis) were tested in this study …
Antileishmanial activity of Urtica dioica extract against zoonotic cutaneous leishmaniasis
PMID: PLoS Negl Trop Dis. 2020 Jan ;14(1):e0007843. Epub 2020 Jan 13. PMID: 31929528 Abstract Title: Antileishmanial activity of Urtica dioica extract against zoonotic cutaneous leishmaniasis. Abstract: BACKGROUND: Neglected parasitic diseases (NTDs) like cutaneous leishmaniasis (CL) have caused high mortality and morbidity rate in developing countries. This disease is considered as one of the six …
Licochalcone A inhibiting proliferation of bladder cancer T24 cells by inducing reactive oxygen species production.
PMID: Biomed Mater Eng. 2014 ;24(1):1019-25. PMID: 24211992 Abstract Title: Licochalcone A inhibiting proliferation of bladder cancer T24 cells by inducing reactive oxygen species production. Abstract: The aim of this study was to determine the relationship between proliferation inhibition and the production of reactive oxygen species (ROS) induced by Licochalcone A (LCA). Cell viability was …
Licochalcone A induces apoptosis through endoplasmic reticulum stress in HepG2 human hepatocellular carcinoma cells.
PMID: Apoptosis. 2014 Apr ;19(4):682-97. PMID: 24337903 Abstract Title: Licochalcone A induces apoptosis through endoplasmic reticulum stress via a phospholipase Cγ1-, Ca(2+)-, and reactive oxygen species-dependent pathway in HepG2 human hepatocellular carcinoma cells. Abstract: Licochalcone A (LicA), an estrogenic flavonoid, induces apoptosis in multiple types of cancer cells. In this study, the molecular mechanisms underlying …