PMID: Tissue Eng Regen Med. 2020 Feb 8. Epub 2020 Feb 8. PMID: 32036567 Abstract Title: Centella asiatica (L.)-Neurodifferentiated Mesenchymal Stem Cells Promote the Regeneration of Peripheral Nerve. Abstract: BACKGROUND: Centella asiatica (L.) is a plant with neuroprotective and neuroregenerative properties; however, its effects on the neurodifferentiation of mesenchymal stem cells (MSCs) and on peripheral …
Author Archives: Taylor Mercado
Inhibitory effect of Centella asiatica extract on DNCB-induced atopic dermatitis.
PMID: Nutrients. 2020 Feb 5 ;12(2). Epub 2020 Feb 5. PMID: 32033291 Abstract Title: Inhibitory Effect of Centella asiatica Extract on DNCB-Induced Atopic Dermatitis in HaCaT Cells and BALB/c Mice. Abstract: Atopic dermatitis (AD) is a chronic inflammatory skin disease caused mainly by immune dysregulation. This study explored the anti-inflammatory and immunomodulatory effects of theethanol …
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This is the first study demonstrating the protective effects of chrysin on the diabetes-associated malfunctioned visual cycle.
PMID: Nutrients. 2018 Aug 8 ;10(8). Epub 2018 Aug 8. PMID: 30096827 Abstract Title: Chrysin Ameliorates Malfunction of Retinoid Visual Cycle through Blocking Activation of AGE-RAGE-ER Stress in Glucose-Stimulated Retinal Pigment Epithelial Cells and Diabetic Eyes. Abstract: Diabetes-associated visual cycle impairment has been implicated in diabetic retinopathy, and chronic hyperglycemia causes detrimental effects on visual …
Citrulline supplementation may be a promising preventive nutritional approach to limit age-related cognitive decline.
PMID: Sci Rep. 2019 Dec 27 ;9(1):20138. Epub 2019 Dec 27. PMID: 31882891 Abstract Title: Citrulline prevents age-related LTP decline in old rats. Abstract: The prevalence of cognitive decline is increasing as the ageing population is considerably growing. Restricting this age-associated process has become a challenging public health issue. The age-related increase in oxidative stress …
L-citrulline supplementation can enhance exercise performance and recovery.
PMID: J Strength Cond Res. 2020 Jan 22. Epub 2020 Jan 22. PMID: 31977835 Abstract Title: Effects of Citrulline Supplementation on Exercise Performance in Humans: A Review of the Current Literature. Abstract: Gonzalez, AM and Trexler, ET. Effects of citrulline supplementation on exercise performance in humans: A review of the current literature. J Strength Cond …
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Improvement in colistin-induced reproductive damage, apoptosis, and autophagy in testes via reducing oxidative stress by chrysin.
PMID: J Biochem Mol Toxicol. 2018 Nov ;32(11):e22201. Epub 2018 Oct 1. PMID: 30273961 Abstract Title: Improvement in colistin-induced reproductive damage, apoptosis, and autophagy in testes via reducing oxidative stress by chrysin. Abstract: This study aimed to investigate the effect of chrysin on colistin-induced reproductive toxicity. Twenty-eight adult male Sprague-Dawley rats were divided into four …
Chrysin leads to cell death in endometriosis by regulation of endoplasmic reticulum stress and cytosolic calcium level.
PMID: J Cell Physiol. 2019 03 ;234(3):2480-2490. Epub 2018 Oct 9. PMID: 30302765 Abstract Title: Chrysin leads to cell death in endometriosis by regulation of endoplasmic reticulum stress and cytosolic calcium level. Abstract: Chrysin is a natural compound derived from honey, propolis, or passion flowers and has many functional roles, such as antiinflammatory and antiangiogenesis …
Chrysin promotes SMMC-7721 cell apoptosis by regulating MAPKs signaling pathway
PMID: Nan Fang Yi Ke Da Xue Xue Bao. 2018 Sep 30 ;38(10):1187-1194. PMID: 30377128 Abstract Title: [Chrysin promotes SMMC-7721 cell apoptosis by regulating MAPKs signaling pathway]. Abstract: OBJECTIVE: To study the effect of chrysin in inducing apoptosis of human hepatic carcinoma cells and explore the possible mechanism.METHODS: Human hepatic carcinoma SMMC-7721 cells treated with …
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Chrysin may serve as a promising therapeutic candidate for inflammatory vascular diseases.
PMID: J Cardiovasc Pharmacol Ther. 2019 05 ;24(3):278-287. Epub 2018 Nov 29. PMID: 30497287 Abstract Title: Chrysin Suppresses Vascular Endothelial Inflammation via Inhibiting the NF-κB Signaling Pathway. Abstract: The vascular endothelium is a continuous layer of flat polygonal cells that are in direct contact with the blood and participate in responses to inflammation. Chrysin is …
Chrysin protects human osteoarthritis chondrocytes by inhibiting inflammatory mediator expression.
PMID: Mol Med Rep. 2019 Feb ;19(2):1222-1229. Epub 2018 Dec 4. PMID: 30535473 Abstract Title: Chrysin protects human osteoarthritis chondrocytes by inhibiting inflammatory mediator expression via HMGB1 suppression. Abstract: High‑mobility group box chromosomal protein (HMGB‑1) contributes to osteoarthritis (OA) by modulating various oxidative, inflammatory and apoptotic signaling pathways. The effect of chrysin (CH), a natural …