Centella asiatica neurodifferentiated mesenchymal stem cells promote the regeneration of peripheral nerve.

PMID:  Tissue Eng Regen Med. 2020 Feb 8. Epub 2020 Feb 8. PMID: 32036567 Abstract Title:  Centella asiatica (L.)-Neurodifferentiated Mesenchymal Stem Cells Promote the Regeneration of Peripheral Nerve. Abstract:  BACKGROUND: Centella asiatica (L.) is a plant with neuroprotective and neuroregenerative properties; however, its effects on the neurodifferentiation of mesenchymal stem cells (MSCs) and on peripheral …

Inhibitory effect of Centella asiatica extract on DNCB-induced atopic dermatitis.

PMID:  Nutrients. 2020 Feb 5 ;12(2). Epub 2020 Feb 5. PMID: 32033291 Abstract Title:  Inhibitory Effect of Centella asiatica Extract on DNCB-Induced Atopic Dermatitis in HaCaT Cells and BALB/c Mice. Abstract:  Atopic dermatitis (AD) is a chronic inflammatory skin disease caused mainly by immune dysregulation. This study explored the anti-inflammatory and immunomodulatory effects of theethanol …

This is the first study demonstrating the protective effects of chrysin on the diabetes-associated malfunctioned visual cycle.

PMID:  Nutrients. 2018 Aug 8 ;10(8). Epub 2018 Aug 8. PMID: 30096827 Abstract Title:  Chrysin Ameliorates Malfunction of Retinoid Visual Cycle through Blocking Activation of AGE-RAGE-ER Stress in Glucose-Stimulated Retinal Pigment Epithelial Cells and Diabetic Eyes. Abstract:  Diabetes-associated visual cycle impairment has been implicated in diabetic retinopathy, and chronic hyperglycemia causes detrimental effects on visual …

Citrulline supplementation may be a promising preventive nutritional approach to limit age-related cognitive decline.

PMID:  Sci Rep. 2019 Dec 27 ;9(1):20138. Epub 2019 Dec 27. PMID: 31882891 Abstract Title:  Citrulline prevents age-related LTP decline in old rats. Abstract:  The prevalence of cognitive decline is increasing as the ageing population is considerably growing. Restricting this age-associated process has become a challenging public health issue. The age-related increase in oxidative stress …

L-citrulline supplementation can enhance exercise performance and recovery.

PMID:  J Strength Cond Res. 2020 Jan 22. Epub 2020 Jan 22. PMID: 31977835 Abstract Title:  Effects of Citrulline Supplementation on Exercise Performance in Humans: A Review of the Current Literature. Abstract:  Gonzalez, AM and Trexler, ET. Effects of citrulline supplementation on exercise performance in humans: A review of the current literature. J Strength Cond …

Improvement in colistin-induced reproductive damage, apoptosis, and autophagy in testes via reducing oxidative stress by chrysin.

PMID:  J Biochem Mol Toxicol. 2018 Nov ;32(11):e22201. Epub 2018 Oct 1. PMID: 30273961 Abstract Title:  Improvement in colistin-induced reproductive damage, apoptosis, and autophagy in testes via reducing oxidative stress by chrysin. Abstract:  This study aimed to investigate the effect of chrysin on colistin-induced reproductive toxicity. Twenty-eight adult male Sprague-Dawley rats were divided into four …

Chrysin leads to cell death in endometriosis by regulation of endoplasmic reticulum stress and cytosolic calcium level.

PMID:  J Cell Physiol. 2019 03 ;234(3):2480-2490. Epub 2018 Oct 9. PMID: 30302765 Abstract Title:  Chrysin leads to cell death in endometriosis by regulation of endoplasmic reticulum stress and cytosolic calcium level. Abstract:  Chrysin is a natural compound derived from honey, propolis, or passion flowers and has many functional roles, such as antiinflammatory and antiangiogenesis …

Chrysin promotes SMMC-7721 cell apoptosis by regulating MAPKs signaling pathway

PMID:  Nan Fang Yi Ke Da Xue Xue Bao. 2018 Sep 30 ;38(10):1187-1194. PMID: 30377128 Abstract Title:  [Chrysin promotes SMMC-7721 cell apoptosis by regulating MAPKs signaling pathway]. Abstract:  OBJECTIVE: To study the effect of chrysin in inducing apoptosis of human hepatic carcinoma cells and explore the possible mechanism.METHODS: Human hepatic carcinoma SMMC-7721 cells treated with …

Chrysin may serve as a promising therapeutic candidate for inflammatory vascular diseases.

PMID:  J Cardiovasc Pharmacol Ther. 2019 05 ;24(3):278-287. Epub 2018 Nov 29. PMID: 30497287 Abstract Title:  Chrysin Suppresses Vascular Endothelial Inflammation via Inhibiting the NF-κB Signaling Pathway. Abstract:  The vascular endothelium is a continuous layer of flat polygonal cells that are in direct contact with the blood and participate in responses to inflammation. Chrysin is …

Chrysin protects human osteoarthritis chondrocytes by inhibiting inflammatory mediator expression.

PMID:  Mol Med Rep. 2019 Feb ;19(2):1222-1229. Epub 2018 Dec 4. PMID: 30535473 Abstract Title:  Chrysin protects human osteoarthritis chondrocytes by inhibiting inflammatory mediator expression via HMGB1 suppression. Abstract:  High‑mobility group box chromosomal protein (HMGB‑1) contributes to osteoarthritis (OA) by modulating various oxidative, inflammatory and apoptotic signaling pathways. The effect of chrysin (CH), a natural …

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