PMID: J Cell Physiol. 2019 Aug ;234(10):17144-17158. Epub 2019 Mar 27. PMID: 30916403 Abstract Title: Impact of chrysin on the molecular mechanisms underlying diabetic complications. Abstract: Diabetes mellitus is a chronic metabolic disorder, resulting in high morbidity and mortality worldwide. Neuropathy, ocular diseases, kidney diseases, and cardiovascular disease are common complications of diabetes that threats …
Author Archives: Taylor Mercado
Chrysin prevents cognitive and hippocampal long-term potentiation deficits and inflammation in rat with cerebral hypoperfusion and reperfusion injury.
PMID: Life Sci. 2019 Jun 1 ;226:202-209. Epub 2019 Apr 13. PMID: 30991061 Abstract Title: Chrysin prevents cognitive and hippocampal long-term potentiation deficits and inflammation in rat with cerebral hypoperfusion and reperfusion injury. Abstract: INTRODUCTION: Ischemic stroke is one of the leading causes of death worldwide, and extensive efforts have focused on the neuroprotective strategies …
Serum lycopene, lutein and zeaxanthin, and the risk of Alzheimer’s disease mortality in older adults.
PMID: Dement Geriatr Cogn Disord. 2014 ;37(3-4):246-56. Epub 2013 Nov 15. PMID: 24247062 Abstract Title: Serum lycopene, lutein and zeaxanthin, and the risk of Alzheimer's disease mortality in older adults. Abstract: BACKGROUND: Oxidative stress is implicated in the pathogenesis of Alzheimer's disease (AD). Accumulating evidence shows that antioxidant-rich food reduces the risk of AD by …
Chrysin inhibits proinflammatory factor-induced EMT phenotype and cancer stem cell-like features in HeLa cells.
PMID: Cell Physiol Biochem. 2019 ;52(5):1236-1250. PMID: 31001962 Abstract Title: Chrysin Inhibits Proinflammatory Factor-Induced EMT Phenotype and Cancer Stem Cell-Like Features in HeLa Cells by Blocking the NF-κB/Twist Axis. Abstract: BACKGROUND/AIMS: TNF-α and TGF-β associated epithelial-mesenchymal transition (EMT) occurs via NF-κB-dependent transcriptional upregulation of Twist1.Chrysin (ChR) is a major active ingredient ofpropolis, which inhibits various …
CBD and GI Health
Research has found CBD may help ease symptoms of GI disorders. As doctors have recently discovered the importance of gut health to your overall health, many patients have turned to CBD to control symptoms of GI illnesses like IBS, Chron’s Disease, Ulcerative Colitis, and Gastritis. CBD’s natural anti-inflammatory properties have been proven to help with …
Therapeutic effects of chrysin in a model of traumatic brain injury
PMID: Life Sci. 2019 Jul 1 ;228:285-294. Epub 2019 May 4. PMID: 31063733 Abstract Title: Therapeutic effects of chrysin in a rat model of traumatic brain injury: A behavioral, biochemical, and histological study. Abstract: AIMS: Oxidative stress and apoptosis have major roles in the progression of traumatic brain injury (TBI)-associated motor and cognitive deficits. The …
Continue reading “Therapeutic effects of chrysin in a model of traumatic brain injury”
Chrysin improved several behavioural, cognitive and neurochemical parameters in a relevant preclinical model of Parkinson’s disease.
n/a PMID: Neurosci Lett. 2019 07 27 ;706:158-163. Epub 2019 May 20. PMID: 31121284 Abstract Title: Chrysin protects against behavioral, cognitive and neurochemical alterations in a 6-hydroxydopamine model of Parkinson's disease. Abstract: Parkinson's disease (PD) is an age-related neurodegenerative disorder that severely affects quality of life of patients and their families. The flavonoid chrysin (5,7-dihydroxylflavone) …
Chrysin inhibits sphere formation in SMMC-7721 cells via modulation of SHP-1/STAT3 signaling pathway
PMID: Cancer Manag Res. 2019 ;11:2977-2985. Epub 2019 Apr 10. PMID: 31114345 Abstract Title: Chrysin inhibits sphere formation in SMMC-7721 cells via modulation of SHP-1/STAT3 signaling pathway. Abstract: Chrysin is a natural flavonoid which has been identified as a candidate anti-cancer agent due to its inhibitory effect on a variety of cancer cells, including targeted …
Vitamin C deficiency-induced pulmonary arterial hypertension.
PMID: Chest. 2020 Feb ;157(2):e21-e23. PMID: 32033656 Abstract Title: Vitamin C Deficiency-Induced Pulmonary Arterial Hypertension. Abstract: We report a case of a man in his 60s who developed pulmonary arterial hypertension (PAH) in association with profound vitamin C deficiency. Decreased availability of endothelial nitric oxide and activation of the hypoxia-inducible family of transcription factors, both …
Continue reading “Vitamin C deficiency-induced pulmonary arterial hypertension.”
Protective effects of p-coumaric acid against acetaminophen-induced hepatotoxicity.
PMID: Food Chem Toxicol. 2018 Nov ;121:131-139. Epub 2018 Aug 24. PMID: 30149109 Abstract Title: Protective effects of p-coumaric acid against acetaminophen-induced hepatotoxicity in mice. Abstract: Acetaminophen (N-acetyl-p-aminophenol, AAP) is an effective analgesic and antipyretic drug with minimal toxicity when used at therapeutic doses. However, AAP overdose is the most common cause of drug-induced acute …
Health Time 