PMID: Eur J Cancer Prev. 2019 Nov ;28(6):472-482. PMID: 30407216 Abstract Title: Supplementation of p-coumaric acid exhibits chemopreventive effect via induction of Nrf2 in a short-term preclinical model of colon cancer. Abstract: Suppression of colorectal cancer by means of chemoprevention is gaining great attention owing to promising outcomes with less adverse effects in preclinical and …
Author Archives: Taylor Mercado
Prophylactic effect and mechanism of p-coumaric acid against hypoxic cerebral edema in mice.
PMID: Respir Physiol Neurobiol. 2019 02 ;260:95-104. Epub 2018 Nov 14. PMID: 30447305 Abstract Title: Prophylactic effect and mechanism of p-coumaric acid against hypoxic cerebral edema in mice. Abstract: Our previous study found that the anti-hypoxia effect of Tibetan turnip (Brassica rapa ssp. rapa) is directly related to its p-Coumaric acid (CA) and glucoside (pCoumaric …
Protective effects of p-coumaric acid against oxidant and hyperlipidemia.
PMID: Biomed Pharmacother. 2019 Mar ;111:579-587. Epub 2018 Dec 31. PMID: 30599319 Abstract Title: Protective effects of p-coumaric acid against oxidant and hyperlipidemia-an in vitro and in vivo evaluation. Abstract: Dietary phenols are antioxidants with diverse physiological functions that are beneficial for human health. The objective of this research work was to investigate antioxidant activity …
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Anti-inflammatory effects of chemical components from Ginkgo biloba L. male flowers on lipopolysaccharide-stimulated RAW264.7 macrophages.
PMID: Phytother Res. 2019 Apr ;33(4):989-997. Epub 2019 Jan 29. PMID: 30693991 Abstract Title: Anti-inflammatory effects of chemical components from Ginkgo biloba L. male flowers on lipopolysaccharide-stimulated RAW264.7 macrophages. Abstract: Ginkgo biloba L., well known as living fossil, have various pharmacological activities. Eighteen compounds were isolated from Ginkgo male flowers including a novel matsutake alcohol …
These preliminary experimental findings demonstrate that naringenin has a certain renoprotective effect on gestational diabetes mellitus.
PMID: Diabetes Metab Syndr Obes. 2020 ;13:53-63. Epub 2020 Jan 8. PMID: 32021351 Abstract Title: The Renoprotective Effects of Naringenin (NGN) in Gestational Pregnancy. Abstract: Introduction: Gestational diabetes mellitus (GDM) is defined as glucose intolerance that is first diagnosed during pregnancy, a condition risking the health of both the mother and the baby. Naringenin (NGN) …
P-coumaric acid attenuates lipopolysaccharide-induced lung inflammation.
PMID: Inflammation. 2019 Dec ;42(6):1939-1950. PMID: 31267276 Abstract Title: p-Coumaric Acid Attenuates Lipopolysaccharide-Induced Lung Inflammation in Rats by Scavenging ROS Production: an In Vivo and In Vitro Study. Abstract: Lipopolysaccharide (LPS), known as lipoglycans and endotoxins found in the cell wall of some type of Gram-negative bacteria, causes acute lung inflammation (ALI). p-Coumaric acid (p-CA) …
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Oral supplementation with p-coumaric acid protects mice against diabetes-associated spontaneous destruction of periodontal tissue.
PMID: J Periodontal Res. 2019 Dec ;54(6):690-701. Epub 2019 Jul 21. PMID: 31328274 Abstract Title: Oral supplementation with p-coumaric acid protects mice against diabetes-associated spontaneous destruction of periodontal tissue. Abstract: OBJECTIVE: Dietary bioactive materials having anti-inflammatory and antioxidant potentials are able to inhibit diabetes-associated periodontal complications. Although numerous studies indicate that administration of p-coumaric acid …
P-coumaric acid inhibits the Listeria monocytogenes RecA protein functions and SOS response: An antimicrobial target.
PMID: Biochem Biophys Res Commun. 2019 Oct 1 ;517(4):655-661. Epub 2019 Aug 13. PMID: 31416617 Abstract Title: p-Coumaric acid inhibits the Listeria monocytogenes RecA protein functions and SOS response: An antimicrobial target. Abstract: Bacterial RecA plays an important role in the evaluation of antibiotic resistance via stress-induced DNA repair mechanism; SOS response. Accordingly, RecA became …
p-Coumaric acid protects cardiac function against lipopolysaccharide-induced acute lung injury by attenuation of oxidative stress.
PMID: Iran J Basic Med Sci. 2019 Aug ;22(8):949-955. PMID: 31579452 Abstract Title: p-Coumaric acid protects cardiac function against lipopolysaccharide-induced acute lung injury by attenuation of oxidative stress. Abstract: Objectives: Acute lung injury (ALI) has a high mortality rate and is characterized by damage to pulmonary system giving rise to symptoms such as histological alteration, …
P-Coumaric acid alleviates experimental diabetic nephropathy.
PMID: Life Sci. 2019 Dec 1 ;238:116965. Epub 2019 Oct 17. PMID: 31629762 Abstract Title: P-Coumaric acid alleviates experimental diabetic nephropathy through modulation of Toll like receptor-4 in rats. Abstract: AIMS: Diabetic nephropathy (DN) is responsible for the occurrence of 30-47% of the incident cases of end-stage renal disease (ESRD) worldwide. DN is a chronic …
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