PMID: Korean J Physiol Pharmacol. 2020 Jan ;24(1):27-37. Epub 2020 Dec 20. PMID: 31908572 Abstract Title: Inhibitory effect of carvacrol on lipopolysaccharide-induced memory impairment in rats. Abstract: Neuroinflammation is an important process underlying a wide variety of neurodegenerative diseases. Carvacrol (CAR) is a phenolic monoterpene commonly used as a food additive due to its antibacterial …
Author Archives: Taylor Mercado
Carvacrol protects against diabetes-induced hypercontractility in the aorta through activation of the PI3K/Akt pathway.
PMID: Biomed Pharmacother. 2020 May ;125:109825. Epub 2020 Feb 7. PMID: 32036208 Abstract Title: Carvacrol protects against diabetes-induced hypercontractility in the aorta through activation of the PI3K/Akt pathway. Abstract: Vascular complications induced by diabetes constitute the principal cause of morbidity and mortality in diabetic patients. It has been reported that carvacrol (CAR) possesses a wide …
Antiproliferative and anti-invasion effects of carvacrol on PC3 human prostate cancer cells.
PMID: Int J Prev Med. 2019 ;10:156. Epub 2019 Oct 9. PMID: 32133074 Abstract Title: Antiproliferative and Anti-invasion Effects of Carvacrol on PC3 Human Prostate Cancer Cells through Reducing pSTAT3, pAKT, and pERK1/2 Signaling Proteins. Abstract: Background: One of the most effective parameters in the progression of the prostate cancer is interleukin (IL)-6 through affecting …
Anti-inflammatory and antioxidant activity of carvacrol in the respiratory system.
PMID: Phytother Res. 2020 Apr 6. Epub 2020 Apr 6. PMID: 32249518 Abstract Title: Anti-inflammatory and antioxidant activity of carvacrol in the respiratory system: A systematic review and meta-analysis. Abstract: Carvacrol is a monoterpene present in the essential oil of a number of plants and has been widely used in traditional medicine because it is …
Carvacrol loaded nanostructured lipid carriers as a promising parenteral formulation for leishmaniasis treatment.
PMID: Eur J Pharm Sci. 2020 Apr 6:105335. Epub 2020 Apr 6. PMID: 32272211 Abstract Title: Carvacrol loaded nanostructured lipid carriers as a promising parenteral formulation for leishmaniasis treatment. Abstract: Leishmaniasis are a group of neglected infectious diseases caused by protozoa of the genus Leishmania with distinct presentations. The available leishmaniasis treatment options are either …
Carvacrol prodrugs with antimicrobial activity loaded on clay nanocomposites.
PMID: Materials (Basel). 2020 Apr 10 ;13(7). Epub 2020 Apr 10. PMID: 32290211 Abstract Title: Carvacrol Prodrugs with Antimicrobial Activity Loaded on Clay Nanocomposites. Abstract: BACKGROUND: Carvacrol, an essential oil with antimicrobial activity against a wide range of pathogens, and its water soluble carvacrol prodrugs (WSCP1-3) were intercalated into montmorillonite (VHS) interlayers to improve their …
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Carvacrol reduces hippocampal cell death and improves learning and memory deficits following lead-induced neurotoxicity via antioxidant activity.
PMID: Naunyn Schmiedebergs Arch Pharmacol. 2020 Apr 17. Epub 2020 Apr 17. PMID: 32303785 Abstract Title: Carvacrol reduces hippocampal cell death and improves learning and memory deficits following lead-induced neurotoxicity via antioxidant activity. Abstract: Carvacrol is a monoterpene with neuroprotective effects in several animal models of neurodegeneration, including epilepsy, ischemia, and traumatic neuronal events. In …
This study provided the evidence regarding the protective effects of carvacrol and thymol against Aβ25–35-induced cytotoxicity in PC12 cells.
PMID: Iran Biomed J. 2020 07 ;24(4):243-50. Epub 2020 Jan 22. PMID: 32306722 Abstract Title: Carvacrol and Thymol Attenuate Cytotoxicity Induced by Amyloidβ25-35 via Activating Protein Kinase C and Inhibiting Oxidative Stress in PC12 Cells. Abstract: Background: Our previous findings indicated that carvacrol and thymol alleviate cognitive impairments caused by Aβ in rodent models of …
Evaluation of the antibacterial activity and efflux pump reversal of thymol and carvacrol against Staphylococcus aureus.
PMID: Molecules. 2020 Apr 30 ;25(9). Epub 2020 Apr 30. PMID: 32365898 Abstract Title: Evaluation of the Antibacterial Activity and Efflux Pump Reversal of Thymol and Carvacrol againstand Their Toxicity in. Abstract: The antibacterial activity and efflux pump reversal of thymol and carvacrol were investigated against theIS-58 strain in this study, as well as their …
Carvacrol exerted an anti-hyperglycemic effect in streptozotocin-induced diabetes.
PMID: BMC Complement Med Ther. 2020 May 11 ;20(1):142. Epub 2020 May 11. PMID: 32393384 Abstract Title: Effect of long-term treatment of Carvacrol on glucose metabolism in Streptozotocin-induced diabetic mice. Abstract: BACKGROUND: Carvacrol is a food additive with various bioactivities, including reducing the blood glucose level as well as improvement of heart function, in diabetic …
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