PMID: Int Immunopharmacol. 2020 Feb ;79:106070. Epub 2020 Jan 6. PMID: 31918062 Abstract Title: Effects of luteolin on treatment of psoriasis by repressing HSP90. Abstract: AIMS: This study was conducted to further clarify the efficacy and potential of luteolin in treating psoriasis and to explore its inner mechanisms.METHODS: A pharmacology network displayed the construction of …
Author Archives: Taylor Mercado
Luteolin prevents intestinal mucositis induced by irinotecan.
PMID: Br J Pharmacol. 2020 Jan 24. Epub 2020 Jan 24. PMID: 31976547 Abstract Title: Luteolin prevents irinotecan-induced intestinal mucositis in mice through antioxidant and anti-inflammatory properties. Abstract: BACKGROUND AND PURPOSE: Intestinal mucositis refers to mucosal damage caused by cancer treatment and irinotecan is one of the agents most associated with this condition. Focusing on …
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Luteolin suppresses bladder cancer growth via regulation of mechanistic target of rapamycin (mTOR) pathway.
PMID: Cancer Sci. 2020 Jan 29. Epub 2020 Jan 29. PMID: 31994822 Abstract Title: Luteolin suppresses bladder cancer growth via regulation of mechanistic target of rapamycin (mTOR) pathway. Abstract: Luteolin is a natural flavonoid with strong anti-oxidative properties that is reported to have an anti-cancer effect in several malignancies other than bladder cancer. In this …
Luteolin-regulated microRNA-301-3p targets caspase-8 and modulates TRAIL sensitivity in PANC-1 cells.
PMID: Anticancer Res. 2020 Feb ;40(2):723-731. PMID: 32014914 Abstract Title: Luteolin-regulated MicroRNA-301-3p Targets Caspase-8 and Modulates TRAIL Sensitivity in PANC-1 Cells. Abstract: BACKGROUND/AIM: MicroRNAs (miRNAs) play regulatory roles in pancreatic ductal adenocarcinoma (PDAC). However, it is still required to identify the function of miRNA-301-3p in pancreatic cancer cells.MATERIALS AND METHODS: Effects of luteolin on cell …
Coenzyme Q10 regulates apoptosis and oxidative stress in hydrogen peroxide induced bone marrow mesenchymal stem cell death.
PMID: Oxid Med Cell Longev. 2019 ;2019:6493081. Epub 2019 Dec 12. PMID: 31915512 Abstract Title: Coenzyme Q10 Regulation of Apoptosis and Oxidative Stress in HOInduced BMSC Death by Modulating the Nrf-2/NQO-1 Signaling Pathway and Its Application in a Model of Spinal Cord Injury. Abstract: Spinal cord injury (SCI) has always been considered to be a …
Coenzyme Q10 attenuates rat hepatocarcinogenesis via the reduction of CD59 expression and phospholipase D activity.
PMID: Cell Biochem Funct. 2020 Jan 27. Epub 2020 Jan 27. PMID: 31989689 Abstract Title: Coenzyme Q10 attenuates rat hepatocarcinogenesis via the reduction of CD59 expression and phospholipase D activity. Abstract: The current study aimed to test the profile of serum lipids, phospholipase D (PLD) activity, and CD59 expression pattern in rat hepatocellular carcinoma (HCC) …
CoQ10 supplementation for three months could improve semen parameters, oxidative stress markers and reduce SDF in infertile men.
PMID: World J Mens Health. 2020 Jan 20. Epub 2020 Jan 20. PMID: 32009311 Abstract Title: Coenzyme Q10 Improves Sperm Parameters, Oxidative Stress Markers and Sperm DNA Fragmentation in Infertile Patients with Idiopathic Oligoasthenozoospermia. Abstract: PURPOSE: Oxidative stress and sperm DNA fragmentation (SDF) are potential contributing factors for idiopathic male infertility. Coenzyme Q10 (CoQ10) have …
Apigenin protects human melanocytes against oxidative damage by activation of the Nrf2 pathway.
PMID: Cell Stress Chaperones. 2020 Jan 18. Epub 2020 Jan 18. PMID: 31953635 Abstract Title: Apigenin protects human melanocytes against oxidative damage by activation of the Nrf2 pathway. Abstract: Vitiligo is a chronic, autoimmune destruction of melanocytes, resulting in progressively expanding depigmented skin patches. Severity of the disorder, which affects approximately 1% of humans, may …
Anthocyanins rich pomegranate cream as a topical formulation with anti-aging activity.
PMID: J Dermatolog Treat. 2020 Feb 5:1-8. Epub 2020 Feb 5. PMID: 32022625 Abstract Title: Anthocyanins rich pomegranate cream as a topical formulation with anti-aging activity. Abstract: Anthocyanins are antioxidant compounds constitute the primary dyes of the pomegranate arils. Anthocyanins could protect the aged skin induced by oxidant exposure as a major role in aging …
Protective effect of royal jelly against diclofenac-induced hepato-renal damage and gastrointestinal ulcerations in rats.
PMID: Heliyon. 2020 Feb ;6(2):e03330. Epub 2020 Feb 1. PMID: 32025584 Abstract Title: Protective effect of royal jelly against diclofenac-induced hepato-renal damage and gastrointestinal ulcerations in rats. Abstract: Objective: Evaluation of traditionally used royal jelly (RJ) for the management of hepato-renal damage and gastrointestinal ulcerations caused by diclofenac.Methods: Forty adult male Wistar rats were allocated …
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