PMID: Cell Death Dis. 2019 04 5 ;10(4):313. Epub 2019 Apr 5. PMID: 30952839 Abstract Title: Nrf2 signaling and autophagy are complementary in protecting lipopolysaccharide/d-galactosamine-induced acute liver injury by licochalcone A. Abstract: Licochalcone A (Lico A), isolated from Xinjiang licorice Glycyrrhiza inflate, has been shown to have antioxidative potential via the activation of nuclear factor-erythroid …
Author Archives: Taylor Mercado
Ursolic acid suppresses cholesterol biosynthesis and exerts anti-cancer effects in hepatocellular carcinoma cells.
PMID: Int J Mol Sci. 2019 Sep 26 ;20(19). Epub 2019 Sep 26. PMID: 31561416 Abstract Title: Ursolic Acid Suppresses Cholesterol Biosynthesis and Exerts Anti-Cancer Effects in Hepatocellular Carcinoma Cells. Abstract: Abnormally upregulated cholesterol and lipid metabolism, observed commonly in multiple cancer types, contributes to cancer development and progression through the activation of oncogenic growth …
Ethanolic extract Ocimum sanctum induces an apoptosis in human lung adenocarcinoma (A549) cells.
PMID: Heliyon. 2019 Nov ;5(11):e02772. Epub 2019 Nov 14. PMID: 31844708 Abstract Title: Ethanolic extract. induces an apoptosis in human lung adenocarcinoma (A549) cells. Abstract: (OS) is tropical herbal plant which is easy to find and widely used as a vegetable food in Indonesia. In last decade, lung adenocarcinoma was in top position as male …
The protective effects of Salvia officinalis essential oil compared to simvastatin against hyperlipidemia.
PMID: J Food Biochem. 2020 Feb 3:e13160. Epub 2020 Feb 3. PMID: 32010989 Abstract Title: The protective effects of Salvia officinalis essential oil compared to simvastatin against hyperlipidemia, liver, and kidney injuries in mice submitted to a high-fat diet. Abstract: The present study was undertaken to evaluate the effects of Salvia officinalis essential oil (SEO) …
Suppressive effects of the standardized extract of Phyllanthus amarus on type II collagen-induced rheumatoid arthritis.
PMID: Curr Pharm Biotechnol. 2018 ;19(14):1156-1169. PMID: 30539691 Abstract Title: Suppressive Effects of the Standardized Extract of Phyllanthus amarus on Type II Collagen-induced Rheumatoid Arthritis in Sprague Dawley Rats. Abstract: BACKGROUND: Standardized extract of Phyllanthus amarus has been shown to possess inhibitory effects on cellular and humoral immune responses in Wistar-Kyoto rats and Balb/c mice.OBJECTIVE: …
Beneficial effects of Phyllanthus amarus leaves on hangover symptoms.
PMID: Pharm Biol. 2019 Dec ;57(1):145-153. PMID: 30922154 Abstract Title: Effects of Phyllanthus amarus PHYLLPROleaves on hangover symptoms: a randomized, double-blind, placebo-controlled crossover study. Abstract: CONTEXT: Phyllanthus amarus Schumach. and Thonn. (Euphorbiaceae) is traditionally known to improve general liver health. However, its effect on hangover is unknown.OBJECTIVE: This study evaluated PHYLLPRO™, a standardized ethanol extract …
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Phyllanthin and hypophyllanthin from Phyllanthus amarus ameliorates immune-inflammatory response in ovalbumin-induced asthma.
PMID: Immunopharmacol Immunotoxicol. 2019 Feb ;41(1):55-67. Epub 2018 Dec 12. PMID: 30541359 Abstract Title: Phyllanthin and hypophyllanthin fromameliorates immune-inflammatory response in ovalbumin-induced asthma: role of IgE, Nrf2, iNOs, TNF-α, and IL's. Abstract: Asthma is a chronic airway immunoinflammatory disorder characterized by airway remodeling.has been reported to possess antioxidant and anti-inflammatory potential.To evaluate the possible mechanism …
Antimicrobial activity of Phyllanthus amarus and inhibition of the NorA efflux pump of Staphylococcus aureus by Phyllanthin.
PMID: Microb Pathog. 2019 May ;130:242-246. Epub 2019 Mar 12. PMID: 30876871 Abstract Title: Antimicrobial activity of Phyllanthus amarus Schumach.&Thonn and inhibition of the NorA efflux pump of Staphylococcus aureus by Phyllanthin. Abstract: The aim of this study was to evaluate the antimicrobial activity of ethanoic extract of P. amarus (PAEE) and its compound Phyllanthin, …
Protective effects of Phyllanthus amarus against lipopolysaccharide-induced neuroinflammation and cognitive impairment.
PMID: Front Pharmacol. 2019 ;10:632. Epub 2019 Jun 4. PMID: 31231221 Abstract Title: Protective Effects ofAgainst Lipopolysaccharide-Induced Neuroinflammation and Cognitive Impairment in Rats. Abstract: (PA) is widely studied for its hepatoprotective properties but has recently received increasing attention due to its diverse anti-inflammatory effects. However, the effects of PA in modulating immune responses in the …
Lignan enriched fraction of Phyllanthus amarus promotes apoptotic cell death in human cervical cancer cells in vitro.
PMID: Sci Rep. 2019 Oct 18 ;9(1):14950. Epub 2019 Oct 18. PMID: 31628385 Abstract Title: Lignan enriched fraction (LRF) of Phyllanthus amarus promotes apoptotic cell death in human cervical cancer cells in vitro. Abstract: Phyllanthus amarus is widely grown in this sub-continent and used traditionally to treat many common ailments. In the present study, lignan …
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