PMID: J Transl Med. 2020 Jan 29 ;18(1):43. Epub 2020 Jan 29. PMID: 31996227 Abstract Title: Lycopene and bone: an in vitro investigation and a pilot prospective clinical study. Abstract: BACKGROUND: There are several effective therapies for osteoporosis but these agents might cause serious adverse events. Lycopene intake could prevent bone loss, however studies on its effects on bone are scarce. …
Author Archives: Taylor Mercado
These findings suggest that these antioxidants might be a potential therapeutic strategy for osteoarthritis.
PMID: Free Radic Biol Med. 2020 Jan 31. Epub 2020 Jan 31. PMID: 32014502 Abstract Title: Natural ingredients-derived antioxidants attenuate HO-induced oxidative stress and have chondroprotective effects on human osteoarthritic chondrocytes via Keap1/Nrf2 pathway. Abstract: Osteoarthritis (OA) is the most common disabling joint disease and its pathological process is closely related to oxidative stress. Recent …
Docosahexaenoic acid protects motor function and increases dopamine synthesis.
PMID: Neuropharmacology. 2020 Jan 27:107976. Epub 2020 Jan 27. PMID: 32001239 Abstract Title: Docosahexaenoic acid protects motor function and increases dopamine synthesis in a rat model of Parkinson's disease via mechanisms associated with increased protein kinase activity in the striatum. Abstract: Parkinson's disease (PD) is a devastating neurodegenerative disease that leads to motor deficits and …
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Brain targeting with docosahexaenoic acid as a prospective therapy for neurodegenerative diseases
PMID: Biochimie. 2020 Jan 31. Epub 2020 Jan 31. PMID: 32014503 Abstract Title: Brain targeting with docosahexaenoic acid as a prospective therapy for neurodegenerative diseases and its passage across blood brain barrier. Abstract: Docosahexaenoic acid (DHA, 22:6n-3) is the main omega-3 polyunsaturated fatty acid in brain tissues necessary for common brain growth and function. DHA …
The results suggest that an acute bout of exercise may attenuate symptoms of environmentally induced dry eye.
PMID: Physiol Rep. 2020 Jan ;8(2):e14262. PMID: 31997577 Abstract Title: The effect of acute exercise on environmentally induced symptoms of dry eye. Abstract: The purpose of this study was to investigate the effects of acute exercise on environmentally induced symptoms of dry eye. Twelve participants without dry eye disease volunteered to complete three experimental visits …
Cytoprotective effects of delphinidin for human chondrocytes against oxidative stress through activation of autophagy.
PMID: Antioxidants (Basel). 2020 Jan 19 ;9(1). Epub 2020 Jan 19. PMID: 31963866 Abstract Title: Cytoprotective Effects of Delphinidin for Human Chondrocytes against Oxidative Stress through Activation of Autophagy. Abstract: Antioxidant enzymes are decreased in osteoarthritis (OA) patients, implying the role of oxidative stress in osteoarthritis pathogenesis. The aim of this study was to evaluate …
The antidiarrhoeal evaluation of Psidium guajava L. against enteropathogenic Escherichia coli induced infectious diarrhoea.
PMID: J Ethnopharmacol. 2020 Jan 10 ;251:112561. Epub 2020 Jan 10. PMID: 31926988 Abstract Title: The antidiarrhoeal evaluation of Psidium guajava L. against enteropathogenic Escherichia coli induced infectious diarrhoea. Abstract: ETHNOPHARMACOLOGICAL RELEVANCE: The plant Psidium guajava L. (Myrtaceae), commonly used as an edible fruit is traditionally used worldwide in treatment of various gastrointestinal problems including …
N-acetylcysteine in the management of acute liver failure from sickle cell hepatic crisis.
PMID: ACG Case Rep J. 2019 Aug ;6(8):e00161. Epub 2019 Aug 21. PMID: 31737700 Abstract Title: N-Acetylcysteine in the Management of Acute Liver Failure From Sickle Cell Hepatic Crisis. Abstract: N-acetylcysteine (NAC) has been well studied in the treatment of acetaminophen-induced and select non-acetaminophen-induced liver failure. However, its role in the management of sickle cell …
N-acetyl-cysteine may be considered as an alternative supplement to metformin in PCOS patients.
PMID: Gynecol Endocrinol. 2019 Nov 21:1-7. Epub 2019 Nov 21. PMID: 31749393 Abstract Title: Comparison of the efficacy between NAC and metformin in treating PCOS patients: a meta-analysis. Abstract: Our aim is to evaluate the clinical effectiveness and safety by comparing N-acetyl-cysteine (NAC) with metformin administrated by polycystic ovary syndrome (PCOS) patients. Systematic review and …
Synergistic effects of N-acetylcysteine and mesenchymal stem cell in a lipopolysaccharide-induced interstitial cystitis.
PMID: Cells. 2019 Dec 29 ;9(1). Epub 2019 Dec 29. PMID: 31905757 Abstract Title: Synergistic Effects of N-Acetylcysteine and Mesenchymal Stem Cell in a Lipopolysaccharide-Induced Interstitial Cystitis Rat Model. Abstract: The purpose of this study was to reduce the amount of stem cells used in treating preclinical interstitial cystitis (IC model) by investigating the synergistic …
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