Prevention and treatment of influenza, influenza-like illness, and common cold by herbal, complementary, and natural therapies.

PMID:  J Evid Based Complementary Altern Med. 2017 Jan ;22(1):166-174. Epub 2016 Apr 6. PMID: 27055821 Abstract Title:  Prevention and Treatment of Influenza, Influenza-Like Illness, and Common Cold by Herbal, Complementary, and Natural Therapies. Abstract:  In recent years viral respiratory tract infections, especially influenza viruses, have had a major impact on communities worldwide as a …

Zinc has a protective effect on spinal cord injury by inhibiting oxidative damage and nlrp3 inflammation.

PMID:  Life Sci. 2020 Jan 22:117351. Epub 2020 Jan 22. PMID: 31981629 Abstract Title:  Zinc promotes functional recovery after spinal cord injury by activating Nrf2/HO-1 defense pathway and inhibiting inflammation of NLRP3 in nerve cells. Abstract:  AIMS: To study the specific therapeutic effect of zinc on spinal cord injury (SCI) and its specific protective mechanism.MAIN …

Zinc treatment was beneficial for sickness behaviour and depressive-like behaviour without concomitant administration of antidepressants.

PMID:  Brain Behav Immun. 2020 Jan 29. Epub 2020 Jan 29. PMID: 32006614 Abstract Title:  Zinc, but not paracetamol, prevents depressive-like behavior and sickness behavior, and inhibits interferon-gamma and astrogliosis in rats. Abstract:  Considering all mental and addictive disorders, depression is the most responsible for years of life lost due to premature mortality and disability. …

2-Ethoxystypandrone from Polygonum cuspidatum, inhibits cell growth and induces apoptosis of liver cancer cells and cancer stem cells.

PMID:  BMC Complement Altern Med. 2019 Feb 1 ;19(1):38. Epub 2019 Feb 1. PMID: 30709346 Abstract Title:  2-Ethoxystypandrone, a novel small-molecule STAT3 signaling inhibitor from Polygonum cuspidatum, inhibits cell growth and induces apoptosis of HCC cells and HCC Cancer stem cells. Abstract:  BACKGROUND: Signal transducer and activator of transcription 3 (STAT3) is an oncogene constitutively …

P. cuspidatum had positive effect on acute gouty arthritis.

PMID:  Zhongguo Zhong Yao Za Zhi. 2019 Feb ;44(3):546-552. PMID: 30989921 Abstract Title:  [Effect of ethanolic extract of Polygonum cuspidatum on acute gouty arthritis in mice through NLRP3/ASC/caspase-1 axis]. Abstract:  The aim of this paper was to study the effect and mechanism of alcohol extract from Polygonum cuspidatum(PCE) on acute gouty arthritis in C57 BL/6 …

Capability of polygonum cuspidatum extract in inhibiting AGEs and preventing diabetes.

PMID:  Food Sci Nutr. 2019 Jun ;7(6):2006-2016. Epub 2019 May 1. PMID: 31289648 Abstract Title:  Capability of polygonum cuspidatum extract in inhibiting AGEs and preventing diabetes. Abstract:  Diabetes is a metabolic disorder disease associated with advanced glycation end products (AGEs) and protein glycation. The effect of polygonum cuspidatum extract (PE) on AGEs and Nε-(Carboxymethyl)-L-lysine formation, …

Polygonum cuspidatum extract attenuates fructose-induced liver lipid accumulation.

PMID:  Phytomedicine. 2019 Oct ;63:152986. Epub 2019 Jun 10. PMID: 31310912 Abstract Title:  Polygonum cuspidatum extract attenuates fructose-induced liver lipid accumulation through inhibiting Keap1 and activating Nrf2 antioxidant pathway. Abstract:  BACKGROUND: Polygonum cuspidatum has been used in traditional Chinese medicine to treat liver disorders associated with oxidative stress, inflammation and lipid accumulation for centuries in …

Antioxidant and Anti-Obesity Activities of Polygonum cuspidatum Extract through Alleviation of Lipid Accumulation on 3T3-L1 Adipocytes.

PMID:  J Microbiol Biotechnol. 2020 Jan 28 ;30(1):21-30. PMID: 31838799 Abstract Title:  Antioxidant and Anti-Obesity Activities ofExtract through Alleviation of Lipid Accumulation on 3T3-L1 Adipocytes. Abstract:  Natural products are widely used due to their various biological activities which include antiinflammatory, antioxidant, and anti-obesity effects. In this study, we determined the antioxidative and anti-obesity effects of50% …

Polyphenols: a diverse class of multi-target anti-HIV-1 agents.

PMID:  Curr Drug Metab. 2013 May ;14(4):392-413. PMID: 23330927 Abstract Title:  Polyphenols: a diverse class of multi-target anti-HIV-1 agents. Abstract:  Polyphenols are a versatile class of compounds that represent secondary metabolites from higher plants and which are abundantly present in the human diet. Epidemiological data suggest protective effects of polyhenols in relation to cancer, cardiovascular …

Virucidal and synergistic activity of polyphenol-rich extracts of seaweeds against measles virus.

PMID:  Viruses. 2018 08 30 ;10(9). Epub 2018 Aug 30. PMID: 30200234 Abstract Title:  Virucidal and Synergistic Activity of Polyphenol-Rich Extracts of Seaweeds against Measles Virus. Abstract:  Although preventable by vaccination, Measles still causes thousands of deaths among young children worldwide. The discovery of new antivirals is a good approach to control new outbreaks that …

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