PMID: Antiviral Res. 2002 Jan ;53(1):19-34. PMID: 11684313 Abstract Title: Inhibitory effects of (-)-epigallocatechin gallate on the life cycle of human immunodeficiency virus type 1 (HIV-1). Abstract: Epigallocatechin gallate (EGCg), the major tea catechin, is known as a potent anti-bacterial agent. In addition, anti-tumor promoting, anti-inflammatory, anti-oxidative and antiviral activities have been reported. In the …
Author Archives: Taylor Mercado
Primary and secondary vaccine failure are the primary reasons for inefficacy of the vaccine.
PMID: Vaccine. 2018 06 18 ;36(26):3721-3726. Epub 2018 May 18. PMID: 29784466 Abstract Title: Knowledge gaps persist and hinder progress in eliminating mumps. Abstract: Mumps, a common childhood disease in the pre-vaccine era that causes swelling of the parotid salivary glands, can lead to orchitis, viral meningitis, and sensorineural deafness. While the incidence of disease …
This study found a 5-fold increased incidence rate for immune thrombocytopenic purpura following a dose of a measles-containing vaccine and a 10.9 increased incidence rate for aseptic meningitis following the first dose of a mumps-containing vaccine.
PMID: Vaccine. 2018 01 8 ;36(3):347-354. Epub 2017 May 27. PMID: 28558983 Abstract Title: Enhancing global vaccine pharmacovigilance: Proof-of-concept study on aseptic meningitis and immune thrombocytopenic purpura following measles-mumps containing vaccination. Abstract: New vaccines designed to prevent diseases endemic in low and middle-income countries (LMICs) are now being introduced without prior record of utilization in …
Further evaluations to better understand the prevalence of mumps virus shedding among vaccinated populations are needed to guide outbreak surveillance and control.
PMID: MMWR Morb Mortal Wkly Rep. 2017 Dec 1 ;66(47):1307-1308. Epub 2017 Dec 1. PMID: 29190262 Abstract Title: Notes from the Field: Absence of Asymptomatic Mumps Virus Shedding Among Vaccinated College Students During a Mumps Outbreak – Washington, February-June 2017. Abstract: [n/a] read more
The Jeryl Lynn mumps vaccine virus poorly induces neutralizing antibodies.
PMID: Vaccine. 2017 07 13 ;35(32):3988-3994. Epub 2017 Jun 13. PMID: 28623030 Abstract Title: Immunogenicity of mumps virus vaccine candidates matching circulating genotypes in the United States and China. Abstract: Mumps virus (MuV) causes acute infection in humans with characteristic swelling of the parotid gland. While vaccination has greatly reduced the incidence of MuV infection, …
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A report of an outbreak of mumps in Ontario in which all confirmed cases had been vaccinated against the disease.
PMID: Clin Vaccine Immunol. 2017 Feb ;24(2). Epub 2017 Feb 6. PMID: 28003216 Abstract Title: Challenges in Interpretation of Diagnostic Test Results in a Mumps Outbreak in a Highly Vaccinated Population. Abstract: In spite of a greatly reduced incidence rate due to vaccination, mumps outbreaks continue to occur in several areas of the world, sometimes …
Mumps outbreaks can occur in highly vaccinated populations. Mumps should be considered in patients with parotitis regardless of vaccination status.
PMID: Clin Infect Dis. 2017 02 15 ;64(4):408-412. PMID: 27927872 Abstract Title: Mumps Outbreak Among a Highly Vaccinated University Community-New York City, January-April 2014. Abstract: Background: On 14 January 2014, a vaccinated student presented with parotitis. Mumps immunoglobulin M (IgM) testing was negative and reverse-transcription polymerase chain reaction (RT-PCR) testing was not performed, resulting in …
Encephalitis with seizures in 5 patients with confirmed mumps vaccine strain in cerebrospinal fluid.
PMID: J Neurol Sci. 2015 Feb 15 ;349(1-2):226-8. Epub 2014 Dec 18. PMID: 25542078 Abstract Title: Clinically mild encephalitis with a reversible splenial lesion (MERS) after mumps vaccination. Abstract: We retrospectively collected three patients with clinically mild encephalitis with a reversible splenial lesion (MERS) after mumps vaccination, and reviewed five patients, including two patients previously …
Another incidence of a mumps outbreak in vaccinated adults.
PMID: Vaccine. 2014 Jul 31 ;32(35):4393-8. Epub 2014 Jun 25. PMID: 24973734 Abstract Title: Mumps increase in Flanders, Belgium, 2012-2013: results from temporary mandatory notification and a cohort study among university students. Abstract: INTRODUCTION: In 2012, an increase in mumps notifications occurred in Belgium, affecting young vaccinated adults. At the end of 2012, a mumps …
Continue reading “Another incidence of a mumps outbreak in vaccinated adults.”
Description of an outbreak in 2009–2010 in the northeastern United States among a highly vaccinated population.
PMID: Emerg Infect Dis. 2014 Apr ;20(4):643-8. PMID: 24655811 Abstract Title: Epidemic of mumps among vaccinated persons, The Netherlands, 2009-2012. Abstract: To analyze the epidemiology of a nationwide mumps epidemic in the Netherlands, we reviewed 1,557 notified mumps cases in persons who had disease onset during September 1, 2009-August 31, 2012. Seasonality peaked in spring …
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