PMID: Mol Carcinog. 2020 Feb ;59(2):168-178. Epub 2019 Nov 25. PMID: 31763724 Abstract Title: Upregulation of DKK3 by miR-483-3p plays an important role in the chemoprevention of colorectal cancer mediated by black raspberry anthocyanins. Abstract: It is reported that black raspberry (BRB) anthocyanins could act as a potential chemopreventive agent for colorectal cancer (CRC). However, …
Author Archives: Taylor Mercado
Black raspberry inhibits oral tumors in mice.
PMID: Cancer Prev Res (Phila). 2020 Jan 22. Epub 2020 Jan 22. PMID: 31969344 Abstract Title: Black Raspberry Inhibits Oral Tumors in Mice Treated with the Tobacco Smoke Constituent Dibenzo(def,p)chrysene via Genetic and Epigenetic Alterations. Abstract: We previously reported that the environmental pollutant and tobacco smoke constituent dibenzo[def,p]chrysene (DBP) induced DNA damage, altered DNA methylation …
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Raspberry Ketone represents a promising gastroprotective activity comparable to omeprazole.
PMID: PLoS One. 2019 ;14(8):e0220548. Epub 2019 Aug 12. PMID: 31404064 Abstract Title: The implication of the crosstalk of Nrf2 with NOXs, and HMGB1 in ethanol-induced gastric ulcer: Potential protective effect is afforded by Raspberry Ketone. Abstract: Ethanol consumption is one of the common causative agents implicated in gastric ulcer development. Oxidative stress plays a …
This is the first study reporting raspberry Ketone hepatoprotective activity in acute hepatic injury and approves its antiapoptotic effect in the liver.
PMID: Toxicol Res (Camb). 2019 Sep 1 ;8(5):663-676. Epub 2019 Jul 1. PMID: 31588343 Abstract Title: Hepatoprotective activity of raspberry ketone is mediatedinhibition of the NF-κB/TNF-α/caspase axis and mitochondrial apoptosis in chemically induced acute liver injury. Abstract: Raspberry Ketone (RK) is a natural phenolic compound which is marketed nowadays as a popular weight-reducing remedy, with …
Curcumol enhances the sensitivity of doxorubicin in triple-negative breast cancer.
PMID: Biochem Pharmacol. 2020 Jan 10 ;174:113795. Epub 2020 Jan 10. PMID: 31926937 Abstract Title: Curcumol enhances the sensitivity of doxorubicin in triple-negative breast cancer via regulating the miR-181b-2-3p-ABCC3 axis. Abstract: Chemoresistance is a major cause of recurrence and poor prognosis in triple-negative breast cancer (TNBC) patients. The essential oil of Rhizoma Curcumae has been …
Curcumol may reverse early and advanced liver fibrogenesis through downregulating the uPA/uPAR pathway.
PMID: Phytother Res. 2020 Jan 27. Epub 2020 Jan 27. PMID: 31989700 Abstract Title: Curcumol may reverse early and advanced liver fibrogenesis through downregulating the uPA/uPAR pathway. Abstract: Previous studies have suggested strong antifibrotic activity of curcumol in the liver; the underlying mechanisms of which, however, remain largely unknown. Aiming to investigate the role of …
Curcumin supplementation has favorable effect on metabolic markers and anthropometric parameters in patients with NAFLD.
PMID: Complement Ther Med. 2020 Jan ;48:102283. Epub 2019 Dec 17. PMID: 31987259 Abstract Title: The effects of curcumin supplementation on liver function, metabolic profile and body composition in patients with non-alcoholic fatty liver disease: A systematic review and meta-analysis of randomized controlled trials. Abstract: BACKGROUND: Non-alcoholic fatty liver disease (NAFLD) is the most common …
Pomegranate extract inhibits migration and invasion of oral cancer cells.
PMID: Environ Toxicol. 2020 Jan 29. Epub 2020 Jan 29. PMID: 31995279 Abstract Title: Pomegranate extract inhibits migration and invasion of oral cancer cells by downregulating matrix metalloproteinase-2/9 and epithelial-mesenchymal transition. Abstract: Discovering drug candidates for the modulation of metastasis is of great importance in inhibiting oral cancer malignancy. Although most pomegranate extract applications aim …
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C. militaris concentrate and cordycepin exhibited significant anticancer effects through their ability to induce apoptosis in breast cancer cells.
PMID: Biomolecules. 2019 Aug 26 ;9(9). Epub 2019 Aug 26. PMID: 31454995 Abstract Title: The Inhibitory Effect of Cordycepin on the Proliferation of MCF-7 Breast Cancer Cells, and its Mechanism: An Investigation Using Network Pharmacology-Based Analysis. Abstract: is a well-known medicinal mushroom. It is non-toxic and has clinical health benefits including cancer inhibition. However, the …
Polysaccharides obtained from mycelia of Cordyceps militaris attenuated doxorubicin-induced cytotoxic effects in chemotherapy.
PMID: Afr Health Sci. 2019 Jun ;19(2):2156-2163. PMID: 31656500 Abstract Title: Polysaccharides obtained fromofattenuated doxorubicin-induced cytotoxic effects in chemotherapy. Abstract: Objectives: militaris has been used as a herbal tonic in traditional Chinese medicine, which could be surface liquid-cultured forproduction. To evaluate the potential of polysaccharides obtained fromof(PS-MCM) for attenuation of side-effects of chemotherapy.Methods: Doxorubicin was …
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