Taylor Mercado

Herd immunity is not a motivator for vaccination.

PMID: Am J Prev Med. 2013 Jul ;45(1):118-121. PMID: 23790997 Abstract Title: Conscious consideration of herd immunity in influenza vaccination decisions. Abstract: BACKGROUND: Influenza vaccination decisions may be influenced by perceived risk reduction related to herd immunity.PURPOSE: This paper examines how free-riding (i.e., foregoing vaccination because of reduced risk perceptions related to herd immunity) or …

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Undervaccinated children have lower outpatient rates.

PMID: JAMA Pediatr. 2013 Mar 1 ;167(3):274-81. PMID: 23338829 Abstract Title: A population-based cohort study of undervaccination in 8 managed care organizations across the United States. Abstract: OBJECTIVES To examine patterns and trends of undervaccination in children aged 2 to 24 months and to compare health care utilization rates between undervaccinated and age-appropriately vaccinated children. …

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Although vaccines may theoretically “eliminate” some strains of viruses, they may be replaced with other strains unaffected by vaccination.

PMID: BMC Public Health. 2012 Oct 16 ;12:878. Epub 2012 Oct 16. PMID: 23072714 Abstract Title: Systematic review of studies evaluating the broader economic impact of vaccination in low and middle income countries. Abstract: BACKGROUND: Most health economic evaluations of childhood vaccination only capture the health and short-term economic benefits. Measuring broader, long-term effects of …

Continue reading “Although vaccines may theoretically “eliminate” some strains of viruses, they may be replaced with other strains unaffected by vaccination.”

Exposure to perifluorinated compounds are associated with reduced humoral responses to vaccines.

PMID: JAMA. 2012 Jan 25 ;307(4):391-7. PMID: 22274686 Abstract Title: Serum vaccine antibody concentrations in children exposed to perfluorinated compounds. Abstract: CONTEXT: Perfluorinated compounds (PFCs) have emerged as important food contaminants. They cause immune suppression in a rodent model at serum concentrations similar to those occurring in the US population, but adverse health effects of …

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Lack of varicella immunity is common in children and adolescents.

PMID: Vaccine. 2011 Oct 13 ;29(44):7835-41. Epub 2011 Aug 2. PMID: 21816197 Abstract Title: Presence of immune memory and immunity to hepatitis B virus in adults after neonatal hepatitis B vaccination. Abstract: Neonatal vaccination against hepatitis B virus (HBV) infection was launched in the 1980s in Qidong, China, where HBV and hepatocellular carcinoma were highly …

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Adults with a previously received seasonal influenza vaccination had a reduced antibody response to the H1N1 vaccine.

PMID: Clin Vaccine Immunol. 2011 Sep ;18(9):1401-5. Epub 2011 Jul 27. PMID: 21795459 Abstract Title: Immunogenicity, boostability, and sustainability of the immune response after vaccination against Influenza A virus (H1N1) 2009 in a healthy population. Abstract: The emergence of a new influenza A virus (H1N1) variant in 2009 led to a worldwide vaccination program, which …

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Immunologic hyporesponsiveness to meningococcal vaccine in African toddlers.

PMID: Clin Vaccine Immunol. 2011 Sep ;18(9):1492-6. Epub 2011 Jul 13. PMID: 21752951 Abstract Title: Meningococcal group C and w135 immunological hyporesponsiveness in african toddlers. Abstract: A phase II clinical study was conducted in African toddlers (aged 12 to 23 months), with subjects receiving either investigational meningococcal group A conjugate (PsA-TT), meningococcal ACWY polysaccharide (PsACWY), …

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Mangifera indica leaf extract was effective in maintaining a long-term hypoglycemic effect and significantly increased insulin sensitivity.

PMID: PLoS One. 2020 ;15(1):e0227105. Epub 2020 Jan 8. PMID: 31914140 Abstract Title: Aqueous extract from Mangifera indica Linn. (Anacardiaceae) leaves exerts long-term hypoglycemic effect, increases insulin sensitivity and plasma insulin levels on diabetic Wistar rats. Abstract: BACKGROUND: Diabetes mellitus is one of the most common todays public health problems. According to a survey by …

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These results suggested that mangiferin serves as a potentially applicable candidate for treating osteoarthritis.

PMID: Oxid Med Cell Longev. 2019 ;2019:8783197. Epub 2019 Oct 15. PMID: 31885823 Abstract Title: Mangiferin Prevents TBHP-Induced Apoptosis and ECM Degradation in Mouse Osteoarthritic Chondrocytes via Restoring Autophagy and Ameliorates Murine Osteoarthritis. Abstract: Osteoarthritis (OA) is an age-related degenerative disease with complicated pathology involving chondrocyte apoptosis and extracellular matrix (ECM) degradation. Previous studies have …

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Mangiferin suppresses human metastatic osteosarcoma cell growth.

PMID: AMB Express. 2020 Jan 18 ;10(1):13. Epub 2020 Jan 18. PMID: 31955303 Abstract Title: Mangiferin suppresses human metastatic osteosarcoma cell growth by down-regulating the expression of metalloproteinases-1/2 and parathyroid hormone receptor 1. Abstract: The study evaluates the protective effect of mangiferin on osteosarcoma cell proliferation and metastasis. Saos-2 and U2OS cells were treated with …

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