PMID: Mol Cell Biochem. 2020 Feb ;465(1-2):65-73. Epub 2020 Jan 1. PMID: 31894530 Abstract Title: Curcumin amends Cadysregulation in microglia by suppressing the activation of P2X7 receptor. Abstract: Curcumin (Cur) is widely used as an anti-inflammation agent and has anti-depression potential. Neuroinflammation mediated by Cachannel activation is closely associated with the progression of post-stroke depression …
Author Archives: Taylor Mercado
Curcumin improved quality of life in liver cirrhotic patients.
PMID: Complement Ther Med. 2020 Mar ;49:102351. Epub 2020 Feb 19. PMID: 32147077 Abstract Title: Curcumin ameliorates health-related quality of life in patients with liver cirrhosis: A randomized, double-blind placebo-controlled trial. Abstract: OBJECTIVES: Current study aimed to find the effects of curcumin on quality of life (QoL) in liver cirrhotic patients.DESIGN: In this randomized double-masked …
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An experimental comparison of the effects of propolis, curcumin, and methylprednisolone on crush injuries of the sciatic nerve.
PMID: Ann Plast Surg. 2015 Jun ;74(6):684-92. PMID: 24317243 Abstract Title: An experimental comparison of the effects of propolis, curcumin, and methylprednisolone on crush injuries of the sciatic nerve. Abstract: BACKGROUND: Propolis and curcumin have antioxidant, anti-inflammatory, immunomodulatory, and neuroprotective features. The goal of this study was to determine the effects of propolis and curcumin …
Immunomodulatory effects of nanocurcumin in arsenic-exposed rats.
PMID: Int Immunopharmacol. 2013 Sep ;17(1):65-70. Epub 2013 Jun 6. PMID: 23747587 Abstract Title: Immunomodulatory effects of nanocurcumin in arsenic-exposed rats. Abstract: We evaluated whether the nanoformulation of curcumin could be more effective than free curcumin against arsenic-induced immune dysfunction in rats. Curcumin was encapsulated in polylactic-co-glycolic acid (PLGA). Nanocurcumin (CUR-NP) exhibited a spherical shape …
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These findings offer curcumin as a new therapeutic agent with the potential of regulating astrocyte-mediated inflammatory diseases in the CNS.
PMID: Int Immunopharmacol. 2014 Sep ;22(1):230-5. Epub 2014 Jul 3. PMID: 24998635 Abstract Title: Study of curcumin immunomodulatory effects on reactive astrocyte cell function. Abstract: Multiple sclerosis (MS) is considered an inflammatory and neurodegenerative disease of the central nervous system (CNS) which most often presents as relapsing-remitting episodes. Recent evidence suggests that activated astrocytes play …
Curcumin has strong antioxidant, with anti-inflammatory, immunomodulatory and analgesic properties.
PMID: Int J Pharm Investig. 2014 Jul ;4(3):138-41. PMID: 25126527 Abstract Title: Comparison of effectiveness of curcumin with triamcinolone acetonide in the gel form in treatment of minor recurrent aphthous stomatitis: A randomized clinical trial. Abstract: INTRODUCTION: Recurrent aphthous stomatitis (RAS) is an unfortunately most common disease occurring in oral cavity. Although the lesion is …
Curcumin loaded solid lipid nanoparticles ameliorate adjuvant-induced arthritis.
PMID: Eur J Pain. 2015 Aug ;19(7):940-52. Epub 2014 Nov 17. PMID: 25400173 Abstract Title: Curcumin loaded solid lipid nanoparticles ameliorate adjuvant-induced arthritis in rats. Abstract: BACKGROUND: Rheumatoid arthritis (RA), a chronic and systemic inflammation, results in destruction of joints and cartilages. Effectiveness of curcumin has been established in a wide variety of inflammatory disorders, …
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The study demonstrated that curcumin was a potent protective compound against the nicotine-induced stress.
PMID: Mol Biol Rep. 2015 Dec ;42(12):1623-37. Epub 2015 Nov 11. PMID: 26559197 Abstract Title: Curcumin protects against nicotine-induced stress during protein malnutrition in female rat through immunomodulation with cellular amelioration. Abstract: Nicotine aggravates many chronic inflammatory disorders in females under the protein-malnourished conditions because women are more susceptible to nicotine-induced diseases due to their …
This study suggests that 25-hydroxyvitamin D treatment may relieve the offspring’s MetS.
PMID: Front Pharmacol. 2020 ;11:97. Epub 2020 Feb 28. PMID: 32184720 Abstract Title: Maternal 25-Hydroxyvitamin D Deficiency Promoted Metabolic Syndrome and Downregulated Nrf2/CBR1 Pathway in Offspring. Abstract: Metabolic syndrome is a disorder of energy use and storage, which is characterized by central obesity, dyslipidemia, and raised blood pressure and blood sugar levels. Maternal 25-hydroxyvitamin D …
Effects of vitamin D supplementation on depression and some involved neurotransmitters.
PMID: J Affect Disord. 2020 May 15 ;269:28-35. Epub 2020 Mar 13. PMID: 32217340 Abstract Title: Effects of vitamin D supplementation on depression and some involved neurotransmitters. Abstract: BACKGROUND: Low vitamin D levels are associated with a dysregulated hypothalamic-pituitary-adrenal (HPA) axis and depression but a causal relationship has not been established. This study aimed to …
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