PMID: Arch Pharm Res. 2020 Jan 27. Epub 2020 Jan 27. PMID: 31989480 Abstract Title: Mangiferin ameliorates placental oxidative stress and activates PI3K/Akt/mTOR pathway in mouse model of preeclampsia. Abstract: Preeclampsia is an inflammatory disease which can induce oxidative stress in placenta. Oxidative stress in preeclampsia is regulated by the phosphatidylinositol-3-kinase/Akt/mammalian target of rapamycin (PI3K/Akt/mTOR) …
Author Archives: Taylor Mercado
These results demonstrated the potentiality of mangiferin from M. indica to control herpes simplex virus replication.
PMID: Bioorg Med Chem. 2020 Feb 15 ;28(4):115304. Epub 2020 Jan 7. PMID: 31956052 Abstract Title: Mangiferin: A promising natural xanthone from Mangifera indica for the control of acyclovir – resistant herpes simplex virus 1 infection. Abstract: Mangiferin is found in many plant species as the mango tree (Mangifera indica) with ethnopharmacological applications and scientific …
Green tea polyphenols decrease weight gain, ameliorate alteration of gut microbiota, and mitigate intestinal inflammation.
PMID: J Nutr Biochem. 2019 Dec 20 ;78:108324. Epub 2019 Dec 20. PMID: 32004926 Abstract Title: Green tea polyphenols decrease weight gain, ameliorate alteration of gut microbiota, and mitigate intestinal inflammation in canines with high-fat-diet-induced obesity. Abstract: Green tea polyphenols (GTPs) exhibit beneficial effects towards obesity and intestinal inflammation; however, the mechanisms and association with …
Tangeretin may play an effective protective role in liver injury.
PMID: J Agric Food Chem. 2018 Jun 27 ;66(25):6317-6325. Epub 2018 Jun 14. PMID: 29871486 Abstract Title: Attenuation of tert-Butyl Hydroperoxide ( t-BHP)-Induced Oxidative Damage in HepG2 Cells by Tangeretin: Relevance of the Nrf2-ARE and MAPK Signaling Pathways. Abstract: The current study evaluates the protective effects of tangeretin, a representative polymethoxyflavone (PMF) mainly isolated from …
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Administration of selenium to type-2 diabetic patients can improve their glycemic and lipidemic profile.
PMID: Cureus. 2019 Dec 22 ;11(12):e6443. Epub 2019 Dec 22. PMID: 31998571 Abstract Title: The Beneficiary Role of Selenium in Type II Diabetes: A Longitudinal Study. Abstract: Introduction Selenium (Se) is an antioxidotic element that is able to protect the pancreatic islets from oxidative stress, improve their functionality, and suspend atherosclerosis. The current paper is …
Nobiletin could alleviate iron overload damage in vascular endothelium.
PMID: Biol Trace Elem Res. 2020 Jan 30. Epub 2020 Jan 30. PMID: 32002792 Abstract Title: Nobiletin Regulates ROS/ADMA/DDAHII/eNOS/NO Pathway and Alleviates Vascular Endothelium Injury by Iron Overload. Abstract: Iron overload is harmful to health and associates with intracellular excessive reactive oxygen species (ROS) generation. Nobiletin (Nob) is known to be antioxidant and anti-inflammatory. However, …
Continue reading “Nobiletin could alleviate iron overload damage in vascular endothelium.”
The results of the study showed that tangeritin is effective in improving cognitive impairments.
PMID: Neurosci Lett. 2019 07 13 ;705:112-117. Epub 2019 Apr 27. PMID: 31039425 Abstract Title: Role of tangeritin against cognitive impairments in transgenic Drosophila model of Parkinson's disease. Abstract: Parkinson's disease (PD) is the second most common neurodegenerative disorder after Alzheimer's disease. As there is no permanent cure for the disease, the use of herbal …
Tangeretin from Citrus reticulate inhibits respiratory syncytial virus replication and associated inflammation in vivo.
n/a PMID: J Agric Food Chem. 2015 Nov 4 ;63(43):9520-7. Epub 2015 Oct 26. PMID: 26468759 Abstract Title: Tangeretin from Citrus reticulate Inhibits Respiratory Syncytial Virus Replication and Associated Inflammation in Vivo. Abstract: Human respiratory syncytial virus (RSV) is a common pathogen that causes pneumonia and bronchiolitis in infants and young children. Our previous study …
Antiviral activity of ginseng extract against respiratory syncytial virus infection.
PMID: Int J Mol Med. 2014 Jul ;34(1):183-90. Epub 2014 Apr 22. PMID: 24756136 Abstract Title: Antiviral activity of ginseng extract against respiratory syncytial virus infection. Abstract: Panax ginseng has been known to have a number of immuno-modulatory effects. In this study, we investigated whether Panax Korean red ginseng extract (KRGE) has in vitro and …
These results suggest that resveratrol-mediated alterations in SARM have therapeutic potential against respiratory syncytial virus immunopathology.
PMID: J Virol. 2014 Apr ;88(8):4229-36. Epub 2014 Jan 29. PMID: 24478430 Abstract Title: Resveratrol inhibits the TRIF-dependent pathway by upregulating sterile alpha and armadillo motif protein, contributing to anti-inflammatory effects after respiratory syncytial virus infection. Abstract: UNLABELLED: Respiratory syncytial virus (RSV) is the most important cause of lower respiratory tract infection in young children …