PMID: Int J Mol Sci. 2020 Jan 8 ;21(2). Epub 2020 Jan 8. PMID: 31936237 Abstract Title: Fecal Microbiota Transplantation Prevents Intestinal Injury, Upregulation of Toll-Like Receptors, and 5-Fluorouracil/Oxaliplatin-Induced Toxicity in Colorectal Cancer. Abstract: FOLFOX (5-fluorouracil, leucovorin, and oxaliplatin), a 5-fluorouracil (5-FU)-based chemotherapy regimen, is one of most common therapeutic regimens for colorectal cancer. However, …
Author Archives: Taylor Mercado
Fecal microbiota transplantation seems to be a promising and safe therapy in the management of ulcerative colitis.
PMID: Acta Gastroenterol Belg. 2019 Oct-Dec;82(4):519-528. PMID: 31950808 Abstract Title: Fecal microbiota transplantation in ulcerative colitis. Abstract: BACKGROUND/STUDY AIMS: Fecal microbiota transplantation (FMT), a treatment aiming to restore dysbiosis by transferring stool from a healthy donor into the patient, has cure rates up to 90% in the management of recurrent Clostridium difficile (C. difficile) diarrhea. …
Berberine regulates fecal metabolites to ameliorate 5-fluorouracil induced intestinal mucositis through modulating gut microbiota
PMID: Biomed Pharmacother. 2020 Jan 17 ;124:109829. Epub 2020 Jan 17. PMID: 31958765 Abstract Title: Berberine regulates fecal metabolites to ameliorate 5-fluorouracil induced intestinal mucositis through modulating gut microbiota. Abstract: Berberine (BBR) is an isoquinoline alkaloid, which has been used in the treatment of intestinal mucositis. However, BBR on chemotherapy-induced mucositis in cancer patients remains …
Distal electroacupuncture at the LI4 acupoint reduces CFA-induced inflammatory pain via the brain TRPV1 signalling pathway.
PMID: Int J Mol Sci. 2019 Sep 10 ;20(18). Epub 2019 Sep 10. PMID: 31510092 Abstract Title: Distal Electroacupuncture at the LI4 Acupoint Reduces CFA-Induced Inflammatory Pain via the Brain TRPV1 Signaling Pathway. Abstract: There is accumulating evidence supporting electroacupuncture's (EA) therapeutic effects. In mice, local EA reliably attenuates inflammatory pain and increases the transient …
Evaluation of the anticonvulsant and anxiolytic-like activities of aqueous leaf extract of Cymbopogon citratus in mice.
PMID: J Basic Clin Physiol Pharmacol. 2019 Nov 14. Epub 2019 Nov 14. PMID: 31730523 Abstract Title: Evaluation of the anticonvulsant and anxiolytic-like activities of aqueous leaf extract of Cymbopogon citratus in mice. Abstract: Background Anxiety is a common ailment of high co-morbidity with epilepsy, a chronic neurologic disease characterized by recurrent seizures. Current drugs …
Lemongrass extract possesses potent anticancer activity against human colon cancers.
PMID: Integr Cancer Ther. 2019 Jan-Dec;18:1534735419889150. PMID: 31845598 Abstract Title: Lemongrass Extract Possesses Potent Anticancer Activity Against Human Colon Cancers, Inhibits Tumorigenesis, Enhances Efficacy of FOLFOX, and Reduces Its Adverse Effects. Abstract: Current chemotherapeutics for metastatic colorectal cancers have limited success and are extremely toxic due to nonselective targeting. Some natural extracts have been traditionally …
Toll-like receptor 2 plays an essential role in electroacupuncture analgesia in a mouse model of inflammatory pain.
PMID: Acupunct Med. 2019 Dec ;37(6):356-364. Epub 2019 Sep 13. PMID: 31517506 Abstract Title: Toll-like receptor 2 plays an essential role in electroacupuncture analgesia in a mouse model of inflammatory pain. Abstract: BACKGROUND: Inflammatory pain occurs when local tissue injury activates macrophages and neutrophils, hence increasing pro-inflammatory cytokine and chemokine levels. Toll-like receptor 2 (TLR2) …
Electroacupuncture treatment can delay the atrophy of gastrocnemius muscle in diabetes.
PMID: Zhen Ci Yan Jiu. 2019 Sept 25;44(9):653-8. PMID: 31532134 Abstract Title: [Effect of electroacupuncture on degradation of myosin heavy chain of gastrocnemius muscle in diabetes rats]. Abstract: OBJECTIVE: To explore the effect of electroacupuncture(EA)on the expression of muscle-specific ring finger protein 1(MuRF1/Trim63),F-box only protein 32(Fbxo32),myosin heavy chain-IIa(Myh2),myosin heavy chain-IIb(Myh4)and myosin heavy chain-I(Myh7)in diabetes rats.METHODS: …
Acupoint electroacupuncture intervention can significantly alleviate the inflammatory reaction of adjuvant arthritis.
PMID: Zhen Ci Yan Jiu. 2019 Sept 25;44(9):659-62. PMID: 31532135 Abstract Title: [Electroacupuncture at"Zusanli"(ST36) and"Xuanzhong"(GB39) improves inflammatory reactions and reduces levels of serum MMP-3 and MMP-9 in adjuvant arthritis rats]. Abstract: OBJECTIVE: To observe the effect of electroacupuncture (EA) at"Zusanli"(ST36) and"Xuanzhong"(GB39) on joint inflammatory reactions and serum matrix metalloproteinase-3 (MMP-3) and MMP-9 contents in rats …
Strawberry and honey polyphenols may potentially prevent the chronic diseases related to oxidative stress and inflammation.
PMID: Phytomedicine. 2020 Jan 11:153170. Epub 2020 Jan 11. PMID: 31980299 Abstract Title: The roles of strawberry and honey phytochemicals on human health: A possible clue on the molecular mechanisms involved in the prevention of oxidative stress and inflammation. Abstract: BACKGROUND: Oxidative stress and inflammation contribute to the etiopathogenesis of several human chronic diseases, such …