Zerumbone exhibits antiphotoaging and dermatoprotective properties in ultraviolet A-irradiated human skin fibroblast cells.

PMID:  Oxid Med Cell Longev. 2019 ;2019:4098674. Epub 2019 Nov 14. PMID: 31814875 Abstract Title:  Zerumbone Exhibits Antiphotoaging and Dermatoprotective Properties in Ultraviolet A-Irradiated Human Skin Fibroblast Cells via the Activation of Nrf2/ARE Defensive Pathway. Abstract:  Ultraviolet A (UVA) irradiation (320-400 nm range) triggers deleterious consequences in skin cell microenvironment leading to skin damage, photoaging (premature …

Atractylenolide II exerted significant anti-tumor effects on gastric carcinoma cells.

PMID:  Molecules. 2017 Nov 3 ;22(11). Epub 2017 Nov 3. PMID: 29099789 Abstract Title:  Atractylenolide II Inhibits Proliferation, Motility and Induces Apoptosis in Human Gastric Carcinoma Cell Lines HGC-27 and AGS. Abstract:  Atractylenolide II (AT-II) exhibits several biological and pharmacological functions, especially anti-cancer activity as the major sesquiterpene lactones isolated from(also namedin Chinese). However, the …

Paeoniflorin inhibits VSMCs proliferation and migration by arresting cell cycle and activating HO-1 through MAPKs and NF-κB pathway.

PMID:  Int Immunopharmacol. 2018 Jan ;54:103-111. Epub 2017 Nov 6. PMID: 29121532 Abstract Title:  Paeoniflorin inhibits VSMCs proliferation and migration by arresting cell cycle and activating HO-1 through MAPKs and NF-κB pathway. Abstract:  The proliferation, migration and inflammation of vascular smooth muscle cells (VSMCs) contributes to the pathogenesis and progression of atherosclerosis. Paeoniflorin (PF) as …

Effect of Atractylodes macrocephala rhizoma on isoproterenol‑induced ventricular remodeling in rats.

PMID:  Mol Med Rep. 2018 Feb ;17(2):2607-2613. Epub 2017 Nov 21. PMID: 29207045 Abstract Title:  Effect of Atractylodes macrocephala rhizoma on isoproterenol‑induced ventricular remodeling in rats. Abstract:  Myocardial infarction (MI) is the primary cause of ventricular remodeling (VR). The aim of the present study was to determine the effect of Atractylodis macrocephalae rhizoma (AMR) on VR induced …

Polysaccharide extracts of Astragalus membranaceus and Atractylodes macrocephala promote intestinal epithelial cell migration.

PMID:  Chin J Nat Med. 2018 Sep ;16(9):674-682. PMID: 30269844 Abstract Title:  Polysaccharide extracts of Astragalus membranaceus and Atractylodes macrocephala promote intestinal epithelial cell migration by activating the polyamine-mediated Kchannel. Abstract:  Astragalus membranaceus (Radix Astragali, RA) and Atractylodes macrocephala (Rhizoma Atractylodis Macrocephalae, RAM) are often used to treat gastrointestinal diseases. In the present study, we …

An alcohol-soluble polysaccharide from Atractylodes macrocephala Koidz induces apoptosis of Eca-109 cells.

PMID:  Carbohydr Polym. 2019 Dec 15 ;226:115136. Epub 2019 Sep 3. PMID: 31582084 Abstract Title:  An alcohol-soluble polysaccharide from Atractylodes macrocephala Koidz induces apoptosis of Eca-109 cells. Abstract:  In this study, polysaccharides from Atractylodes macrocephala Koidz (APA) which were soluble in alcohol were prepared, purified, analyzed the structure and investigated the antitumor activity in vitro …

Atractylodes macrocephala may prove to be a potential candidate in cancer immunotherapy.

PMID:  Onco Targets Ther. 2019 ;12:7111-7121. Epub 2019 Sep 4. PMID: 31564895 Abstract Title:  polysaccharides regulate the innate immunity of colorectal cancer cells by modulating the TLR4 signaling pathway. Abstract:  Background: It has been well-recognized that the polysaccharides from(PAM) are immune system enhancers, which can facilitate the proliferation of lymphocytes and stimulate immune cells. Nevertheless, …

Atractylodes macrocephala can inhibit the proliferation and invasion of hepatocellular carcinoma cells.

PMID:  Nan Fang Yi Ke Da Xue Xue Bao. 2019 Oct 30 ;39(10):1180-1185. PMID: 31801717 Abstract Title:  [Effect of Atractylodes macrocephala polysaccharide on proliferation and invasion of hepatocellular carcinoma cells]. Abstract:  OBJECTIVE: To investigate the inhibitory effect of polysaccharide of Atractylodes macrocephala (PAM) on the proliferation and invasion of hepatocellular carcinoma cells and the underlying …

The present study demonstrated that caffeic acid is a promising candidate for P-gp inhibition and cancer multidrug resistance attenuation.

PMID:  Molecules. 2020 Jan 7 ;25(2). Epub 2020 Jan 7. PMID: 31936160 Abstract Title:  Caffeic Acid Attenuates Multi-Drug Resistance in Cancer Cells by Inhibiting Efflux Function of Human P-glycoprotein. Abstract:  Multidrug resistance (MDR) is a complicated ever-changing problem in cancer treatment, and P-glycoprotein (P-gp), a drug efflux pump, is regarded as the major cause. In …

Acute kidney injury and hepatitis associated with energy drink consumption: a case report.

PMID:  J Med Case Rep. 2020 Jan 29 ;14(1):23. Epub 2020 Jan 29. PMID: 31992329 Abstract Title:  Acute kidney injury and hepatitis associated with energy drink consumption: a case report. Abstract:  INTRODUCTION: In the USA, energy drinks are commonly consumed among adults. The side effects of these drinks are not well studied but consumers have …

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