PMID: Int J Biol Macromol. 2020 Jan 20. Epub 2020 Jan 20. PMID: 31972198 Abstract Title: Gastric protective activities of fucoidan from brown alga Kjellmaniella crassifolia through the NF-κB signaling pathway. Abstract: Fucoidan has been reported to have abundant biological activities. The objective of the present study was to detect the protective effects of fucoidan …
Author Archives: Taylor Mercado
Dietary fucoxanthin induces anoikis in colorectal adenocarcinoma by suppressing integrin signalling in a murine colorectal cancer model.
PMID: J Clin Med. 2019 Dec 29 ;9(1). Epub 2019 Dec 29. PMID: 31905803 Abstract Title: Dietary Fucoxanthin Induces Anoikis in Colorectal Adenocarcinoma by Suppressing Integrin Signaling in a Murine Colorectal Cancer Model. Abstract: Fucoxanthin (Fx), abundantly contained in edible brown algae, is a carotenoid with strong anti-cancer potential. Anoikis is an anchor-dependent apoptosis particularly …
Health benefits of fucoxanthin in the prevention of chronic diseases.
PMID: Biochim Biophys Acta Mol Cell Biol Lipids. 2020 Jan 10:158618. Epub 2020 Jan 10. PMID: 31931174 Abstract Title: Health benefits of fucoxanthin in the prevention of chronic diseases. Abstract: Fucoxanthin is a xanthophyll carotenoid abundant in macroalgae, such as brown seaweeds. When fucoxanthin is consumed, it can be esterified or hydrolyzed to fucoxanthinol in …
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Chlorogenic acid could be a potential therapeutic to minimize sodium arsenite-induced hepatic injury.
PMID: Mol Biol Rep. 2020 Feb ;47(2):1161-1171. Epub 2019 Dec 9. PMID: 31820315 Abstract Title: Chlorogenic acid prevents hepatotoxicity in arsenic-treated mice: role of oxidative stress and apoptosis. Abstract: Arsenic is a potent and toxic heavy metal found in the environment that causes health problems, including liver disease, in humans and animals. Chlorogenic acid (CA) …
Cytotoxic withanolides from the roots of Withania somnifera.
PMID: J Nat Prod. 2019 Apr 26 ;82(4):765-773. Epub 2019 Feb 18. PMID: 30776236 Abstract Title: Cytotoxic Withanolides from the Roots of Indian Ginseng ( Withania somnifera). Abstract: Withania somnifera, commonly known as"Indian ginseng"or"ashwagandha", is popular as a functional food because of its diverse purported therapeutic efficacies including invigorating, improvement of cognitive ability, and stress …
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Identification of withaferin A as a potential candidate for anti-cancer therapy in non-small cell lung cancer.
PMID: Cancers (Basel). 2019 Jul 17 ;11(7). Epub 2019 Jul 17. PMID: 31319622 Abstract Title: Identification of Withaferin A as a Potential Candidate for Anti-Cancer Therapy in Non-Small Cell Lung Cancer. Abstract: Low response rate and recurrence are common issues in lung cancer; thus, identifying a potential compound for these patients is essential. Utilizing an …
Withaferin A triggers G2/M arrest and intrinsic apoptosis in glioblastoma cells.
PMID: Cell Prolif. 2020 Jan ;53(1):e12706. Epub 2019 Oct 23. PMID: 31642559 Abstract Title: Withaferin A triggers G2/M arrest and intrinsic apoptosis in glioblastoma cells via ATF4-ATF3-CHOP axis. Abstract: OBJECTIVE: Withaferin A (WA) is a bioactive compound with a remarkable anti-cancer effect derived from Withania somnifera, commonly known as ashwagandha. However, the anti-cancer mechanisms of …
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Ashwagandha could be of potential use to improve sleep parameters in patients with insomnia and anxiety.
PMID: Cureus. 2019 Sep 28 ;11(9):e5797. Epub 2019 Sep 28. PMID: 31728244 Abstract Title: Efficacy and Safety of Ashwagandha (Withania somnifera) Root Extract in Insomnia and Anxiety: A Double-blind, Randomized, Placebo-controlled Study. Abstract: Introduction Insomnia is a prevalent sleep disorder that can profoundly impact a person's physical health and mental wellbeing. Most of the currently …
Withania Somnifera and withaferin A: potential in integrative oncology.
PMID: Int J Mol Sci. 2019 Oct 25 ;20(21). Epub 2019 Oct 25. PMID: 31731424 Abstract Title: (Ashwagandha) and Withaferin A: Potential in Integrative Oncology. Abstract: Ashwagandha (, belonging to the family Solanaceae, is an Ayurvedic herb known worldwide for its numerous beneficial health activities since ancient times. This medicinal plant provides benefits against many …
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H. Pylori Treatment, Garlic and Vitamin Supplementation Slash Gastric Cancer Incidence and Death
In a long-term study, Chinese researchers find that conventional options may not be the only effective treatment for and prevention of gastric cancer
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