Effect of quercetin rich onion extracts on bacterial quorum sensing.

PMID:  Front Microbiol. 2019 ;10:867. Epub 2019 Apr 24. PMID: 31105665 Abstract Title:  Effect of Quercetin Rich Onion Extracts on Bacterial Quorum Sensing. Abstract:  Quorum sensing (QS) regulates bacterial gene expression and studies suggest quercetin, a flavonol found in onion, as a QS inhibitor. There are no studies showing the anti-QS activity of plants containing …

Onion bulb extract reduces colitis severity in mice.

PMID:  J Ethnopharmacol. 2019 Sep 15 ;241:112008. Epub 2019 May 31. PMID: 31158441 Abstract Title:  Onion bulb extract reduces colitis severity in mice via modulation of colonic inflammatory pathways and the apoptotic machinery. Abstract:  ETHNOPHARMACOLOGICAL RELEVANCE: The use of nutraceutical-based products has increased in recent years due to their demonstrated efficacy and their good safety …

Onion peel extract has beneficial effects on obesity by regulating erythrocyte n-6/n-3 ratio and preventing fat accumulation in various body regions.

PMID:  J Med Food. 2020 Jan ;23(1):37-42. Epub 2019 Dec 19. PMID: 31855493 Abstract Title:  Onion Peel Extract Increases Erythrocyte Membrane n-3 Fatty Acids in Overweight and Obese Korean Subjects. Abstract:  The association between obesity and erythrocyte fatty acids (FAs) has been suggested; however, there have been no studies on the effects of onion peel …

Beneficial effects of fish oil enriched in omega-3 fatty acids on the development and maintenance of neuropathic pain.

PMID:  J Pharm Pharmacol. 2019 Dec 26. Epub 2019 Dec 26. PMID: 31876957 Abstract Title:  Beneficial effects of fish oil enriched in omega-3 fatty acids on the development and maintenance of neuropathic pain. Abstract:  OBJECTIVE: The aim of this work was to assess the preventive effect of an eicosapentaenoic acid/docosahexaenoic acid-concentrate fish oil on neuropathic …

Addition of docosahexaenoic acid synergistically enhances the efficacy of apatinib for triple-negative breast cancer therapy.

PMID:  Biosci Biotechnol Biochem. 2019 Dec 31:1-14. Epub 2019 Dec 31. PMID: 31889475 Abstract Title:  Addition of docosahexaenoic acid synergistically enhances the efficacy of apatinib for triple-negative breast cancer therapy. Abstract:  The current study aimed to investigate the antitumor and antiangiogenesis effects of apatinib in triple-negative breast cancer in vitro and also whether the combination …

DHA supplementation impeded IFN and chemokine gene expression associated with lupus flaring and nephritis.

PMID:  Front Immunol. 2019 ;10:2851. Epub 2019 Dec 13. PMID: 31921124 Abstract Title:  Docosahexaenoic Acid Consumption Impedes Early Interferon- and Chemokine-Related Gene Expression While Suppressing Silica-Triggered Flaring of Murine Lupus. Abstract:  Exposure of lupus-prone female NZBWF1 mice to respirable crystalline silica (cSiO), a known human autoimmune trigger, initiates loss of tolerance, rapid progression of autoimmunity, …

DHA may be beneficial in preventing chronic pancreatitis by suppressing pancreatic expression of fibrotic mediators.

PMID:  J Cancer Prev. 2019 Dec ;24(4):233-239. Epub 2019 Dec 30. PMID: 31950023 Abstract Title:  Docosahexaenoic Acid Inhibits Expression of Fibrotic Mediators in Mice With Chronic Pancreatitis. Abstract:  Background: Chronic pancreatitis (CP) is an irreversible progressive disease that destroys exocrine parenchyma, which are replaced by fibrous tissue. As pancreatic fibrosis is a key feature of …

Docosahexaenoic acid attenuates mitochondrial alterations and oxidative stress leading to cell death Induced by very long-chain fatty acids.

PMID:  Int J Mol Sci. 2020 Jan 18 ;21(2). Epub 2020 Jan 18. PMID: 31963714 Abstract Title:  Docosahexaenoic Acid Attenuates Mitochondrial Alterations and Oxidative Stress Leading to Cell Death Induced by Very Long-Chain Fatty Acids in a Mouse Oligodendrocyte Model. Abstract:  In the case of neurodegenerative pathologies, the therapeutic arsenal available is often directed towards …

Docosahexaenoic acid: Outlining the therapeutic nutrient potential to combat the prenatal alcohol-induced insults on brain development.

PMID:  Adv Nutr. 2020 Jan 27. Epub 2020 Jan 27. PMID: 31989167 Abstract Title:  Docosahexaenoic Acid: Outlining the Therapeutic Nutrient Potential to Combat the Prenatal Alcohol-Induced Insults on Brain Development. Abstract:  Brain development is markedly affected by prenatal alcohol exposure, leading to cognitive and behavioral problems in the children. Protecting neuronal damage from prenatal alcohol …

Polyunsaturated fatty acids and DNA methylation in colorectal cancer

PMID:  World J Clin Cases. 2019 Dec 26 ;7(24):4172-4185. PMID: 31911898 Abstract Title:  Polyunsaturated fatty acids and DNA methylation in colorectal cancer. Abstract:  Colorectal cancer (CRC) has been designated a major global problem, especially due to its high prevalence in developed countries. CRC mostly occurs sporadically (75%-80%), and only 20%-25% of patients have a family …

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