Sedentary behaviour is associated with depression symptoms.

PMID:  J Affect Disord. 2020 Jan 10 ;265:59-62. Epub 2020 Jan 10. PMID: 31959584 Abstract Title:  Sedentary behaviour is associated with depression symptoms: Compositional data analysis from a representative sample of 3233 US adults and older adults assessed with accelerometers. Abstract:  BACKGROUND: Evidence supporting the individual associations of sedentary behaviours with depression symptoms commonly ignores …

Curcumin can act as a suitable therapeutic agent against sepsis-induced chronic lung injury.

PMID:  J Nutr Health Aging. 2017 ;21(3):307-313. PMID: 28244571 Abstract Title:  Efficacy and Therapeutic Potential of Curcumin Against Sepsis-Induced Chronic Lung Injury in Male Albino Rats. Abstract:  The present study investigates curcumin effect against sepsis-induced chronic lung injury (CLI) of male albino rats. Rats were grouped into four groups such rats undergoing a sham cecal …

Effect of combined calcium, magnesium, vitamin C and E on seminal parameters and serum oxidative stress markers in fructose-induced diabetic rats.

PMID:  Arch Physiol Biochem. 2020 Jan 25:1-8. Epub 2020 Jan 25. PMID: 31983250 Abstract Title:  Effect of combined calcium, magnesium, vitamin C and E supplementation on seminal parameters and serum oxidative stress markers in fructose-induced diabetic Wistar rats. Abstract:  Deleterious effects of diabetes on seminal quality, serum metals and antioxidants have been confirmed.This study evaluated …

This large cohort study supports an association between cycling to work and reduced all-cause mortality.

PMID:  Int J Epidemiol. 2020 Jan 13. Epub 2020 Jan 13. PMID: 31930316 Abstract Title:  Is mode of transport to work associated with mortality in the working-age population? Repeated census-cohort studies in New Zealand 1996, 2001 and 2006. Abstract:  BACKGROUND: Increasing active transport is proposed as a means to address both health and environmental issues. …

N-acetylcysteine inhibits thrombosis in a murine model of myeloproliferative neoplasm.

PMID:  Blood Adv. 2020 Jan 28 ;4(2):312-321. PMID: 31978215 Abstract Title:  N-acetylcysteine inhibits thrombosis in a murine model of myeloproliferative neoplasm. Abstract:  Thrombosis is a major cause of mortality in patients with myeloproliferative neoplasms (MPNs), though there is currently little to offer patients with MPN beyond aspirin and cytoreductive therapies such as hydroxyurea for primary …

Protective effects of luteolin on injury induced inflammation through reduction of tissue uric acid and pro-inflammatory cytokines.

PMID:  J Tradit Complement Med. 2020 Jan ;10(1):60-69. Epub 2019 Feb 27. PMID: 31956559 Abstract Title:  Protective effects of luteolin on injury induced inflammation through reduction of tissue uric acid and pro-inflammatory cytokines in rats. Abstract:  Background and aim: Luteolin belongs to flavone group of flavonoids, present in many plants with potent antioxidant, anti-inflammatory and …

NAC may represent a promising strategy for conserving brain health against metabolic diseases-induced neurodegeneration.

PMID:  Arch Biochem Biophys. 2019 Dec 12 ;680:108227. Epub 2019 Dec 12. PMID: 31838118 Abstract Title:  Redox status, inflammation, necroptosis and inflammasome as indispensable contributors to high fat diet (HFD)-induced neurodegeneration; Effect of N-acetylcysteine (NAC). Abstract:  Adequate dietary intake has a crucial effect on brain health. High fat diet (HFD) rich in saturated fatty acids …

Treatment with NAC may help to reduce oxidative and inflammatory damage in pneumonia patients.

PMID:  Medicine (Baltimore). 2018 Nov ;97(45):e13087. PMID: 30407312 Abstract Title:  N-acetylcysteine improves oxidative stress and inflammatory response in patients with community acquired pneumonia: A randomized controlled trial. Abstract:  Oxidative stress is considered to be part of the pathogenic mechanism for community-acquired pneumonia (CAP) and is closely linked to inflammation. Attenuation of oxidative stress would be …

Protective effect of N-acetyl cysteine against radiotherapy-induced cardiac damage.

PMID:  Int J Radiat Biol. 2020 Jan 28:1-32. Epub 2020 Jan 28. PMID: 31990607 Abstract Title:  Protective effect of N-acetyl cysteine against radiotherapy-induced cardiac damage. Abstract:  Although radiotherapy (RT) is an important component of cancer treatment, it induces adverse tissue reactions in the around of cancer tissue. Therefore, radioprotectives are needed to protect normal tissues. …

Piperine ameliorated the progression of TNBS-induced colitis.

PMID:  Hum Exp Toxicol. 2019 Dec 13:960327119892042. Epub 2019 Dec 13. PMID: 31835924 Abstract Title:  Piperine, a functional food alkaloid, exhibits inhibitory potential against TNBS-induced colitis via the inhibition of IκB-α/NF-κB and induces tight junction protein (claudin-1, occludin, and ZO-1) signaling pathway in experimental mice. Abstract:  BACKGROUND: Inflammatory bowel disease is a chronic immunoinflammatory disease …

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