Folic acid supplementation could be used to effectively counteract sleep deprivation-induced telomere dysfunction and the associated aging phenotype.

PMID:  Oxid Med Cell Longev. 2019 ;2019:4569614. Epub 2019 Dec 14. PMID: 31949878 Abstract Title:  Folic Acid Supplementation Suppresses Sleep Deprivation-Induced Telomere Dysfunction and Senescence-Associated Secretory Phenotype (SASP). Abstract:  Sleep deprivation is reported to cause oxidative stress and is hypothesized to induce subsequent aging-related diseases including chronic inflammation, Alzheimer's disease, and cardiovascular disease. However, how …

Postischemic supplementation of folic acid improves neuronal survival and regeneration in vitro.

PMID:  Nutr Res. 2019 Dec 23 ;75:1-14. Epub 2019 Dec 23. PMID: 31955011 Abstract Title:  Postischemic supplementation of folic acid improves neuronal survival and regeneration in vitro. Abstract:  Supplementation of folic acid (FA) is beneficial to several neurological diseases because it promotes notch signaling and neurogenesis and reduces blood homocysteine levels. We hypothesized that postischemic …

Folic acid and melatonin mitigate diabetic nephropathy in rats via inhibition of oxidative stress.

PMID:  Nutr Metab (Lond). 2020 ;17:6. Epub 2020 Jan 14. PMID: 31956332 Abstract Title:  Folic acid and melatonin mitigate diabetic nephropathy in rats via inhibition of oxidative stress. Abstract:  Background: Diabetes mellitus is a global epidemic leads to multiple serious health complications, including nephropathy. Diabetic nephropathy is a serious kidney-related complication of type 1 or …

These results suggest a protective effect of folic acid supplement use on risk of small for gestational age.

PMID:  Int J Environ Res Public Health. 2020 01 19 ;17(2). Epub 2020 Jan 19. PMID: 31963813 Abstract Title:  Dietary Folate Intake and Folic Acid Supplements among Pregnant Women from Southern Italy: Evidence from the"Mamma&Bambino"Cohort. Abstract:  Folate requirement among women who plan to become pregnant should be raised to 600μg/day during the periconceptional period. To …

Folic acid modulates matrix metalloproteinase-9 expression following spinal cord injury.

PMID:  Ann Neurosci. 2019 Apr ;26(2):60-65. Epub 2019 Apr 1. PMID: 31975775 Abstract Title:  Folic Acid Modulates Matrix Metalloproteinase-9 Expression Following Spinal Cord Injury. Abstract:  Background: Treatment of spinal cord injury (SCI) induced neuropathic pain (NP) proves to be extremely clinically challenging as the mechanism behind SCINP is poorly understood. Matrix metalloproteinase (MMP) is largely …

High dosage of folic acid supplement from 3 months before pregnancy until the entire pregnancy reduces the recurrent pre-eclampsia.

PMID:  Pregnancy Hypertens. 2020 Jan 14. Epub 2020 Jan 14. PMID: 31987769 Abstract Title:  The effect of folic acid throughout pregnancy among pregnant women at high risk of pre-eclampsia: A randomized clinical trial. Abstract:  BACKGROUND: Pre-eclampsia is a serious hypertension disease that occurs during pregnancy. Folic acid (FA) supplementation has been reported to reduce pre-eclampsia …

Preclinical pharmacological activities of epigallocatechin-3-gallate in signalling pathways: An update on cancer.

PMID:  Molecules. 2020 Jan 22 ;25(3). Epub 2020 Jan 22. PMID: 31979082 Abstract Title:  Preclinical Pharmacological Activities of Epigallocatechin-3-gallate in Signaling Pathways: An Update on Cancer. Abstract:  Epigallocatechin gallate (EGCG) is the main bioactive component of catechins predominantly present in svarious types of teas. EGCG is well known for a wide spectrum of biological activity …

The potential role of tea in periodontal therapy: An updated review.

PMID:  Curr Drug Discov Technol. 2020 Jan 26. Epub 2020 Jan 26. PMID: 31985382 Abstract Title:  The potential role of tea in periodontal therapy: An updated review. Abstract:  Periodontal diseases are highly prevalent and can affect high percentage of the world population. Oxidative stress and inflammation plays an important role in the pathogenesis of periodontal …

Phloretin protects macrophages from E. coli-induced inflammation through the TLR4 signaling pathway.

PMID:  J Microbiol Biotechnol. 2019 Dec 30. Epub 2019 Dec 30. PMID: 31893612 Abstract Title:  Phloretin protects macrophages from-induced inflammation through the TLR4 signaling pathway. Abstract:  Macrophages are the cells of the first-line defense system, which protect the body from foreign invaders such as bacteria. However, Gram-negative bacteria have always been the major challenge for …

Fig leaf tea suppresses allergy by acceleration disassembly of IgE-receptor complexes.

PMID:  Biosci Biotechnol Biochem. 2020 Jan 27:1-10. Epub 2020 Jan 27. PMID: 31987005 Abstract Title:  Fig (L.) leaf tea suppresses allergy by acceleration disassembly of IgE-receptor complexes. Abstract:  In this study, I investigated the allergy suppressive effect of tea made from fig (L.) leaves. In the rat basophil cell line RBL-2H3, degranulation was significantly suppressed …

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