Ginsenoside Rg3 attenuates the osimertinib resistance by reducing the stemness of non-small cell lung cancer cells.

PMID:  Environ Toxicol. 2020 Jan 9. Epub 2020 Jan 9. PMID: 31916386 Abstract Title:  Ginsenoside Rg3 attenuates the osimertinib resistance by reducing the stemness of non-small cell lung cancer cells. Abstract:  In the present study, we found that Ginsenoside Rg3 attenuated the stemness of non-small cell lung cancer (NSCLC) cells, evident by decreasing spheroid formation …

Ginsenoside Rg3 can inhibit expression of HIF-1α and VEGF in human gastric cancer cells

PMID:  J Cancer Res Ther. 2019 ;15(7):1642-1646. PMID: 31939450 Abstract Title:  Inhibition of the hypoxia-induced factor-1α and vascular endothelial growth factor expression through ginsenoside Rg3 in human gastric cancer cells. Abstract:  Objective: The aim of this study is to probe in the inhibitory effects of ginsenoside Rg3 on the expression of hypoxia-induced factor-1α (HIF-1α) and …

Ginsenoside Rg5 could be a potential therapeutic agent for breast cancer treatment.

PMID:  Nutrients. 2020 Jan 18 ;12(1). Epub 2020 Jan 18. PMID: 31963684 Abstract Title:  The Preparation of Ginsenoside Rg5, Its Antitumor Activity against Breast Cancer Cells and Its Targeting of PI3K. Abstract:  Ginsenosides have been reported to possess various pharmacological effects, including anticancer effects. Nevertheless, there are few reports about the antitumor activity and mechanisms …

Acute effects of air pollutants on daily mortality and hospitalizations due to cardiovascular and respiratory diseases.

PMID:  J Thorac Dis. 2019 Jul ;11(7):3070-3083. PMID: 31463136 Abstract Title:  Acute effects of air pollutants on daily mortality and hospitalizations due to cardiovascular and respiratory diseases. Abstract:  Background: Chiang Dao is one of the districts in Chiang Mai, Thailand facing high level of seasonal air pollution every year, the exposure of community dwellers to …

Particulate air pollution in Ho Chi Minh city and risk of hospital admission for acute lower respiratory infection among young children.

PMID:  Environ Pollut. 2020 Feb ;257:113424. Epub 2019 Oct 18. PMID: 31672367 Abstract Title:  Particulate air pollution in Ho Chi Minh city and risk of hospital admission for acute lower respiratory infection (ALRI) among young children. Abstract:  High levels of air pollutants in Vietnam, especially particulate matters including PM, can be important risk factors for …

The association of childhood pneumonia with household air pollution in Nepal.

PMID:  Matern Child Health J. 2020 Jan 24. Epub 2020 Jan 24. PMID: 31981064 Abstract Title:  The Association of Childhood Pneumonia with Household Air Pollution in Nepal: Evidence from Nepal Demographic Health Surveys. Abstract:  INTRODUCTION: Childhood pneumonia is a major cause of mortality worldwide while household air pollution (HAP) is a major contributor to childhood …

Emerging role of air pollution in autoimmune diseases.

PMID:  Autoimmun Rev. 2019 Jun ;18(6):607-614. Epub 2019 Apr 5. PMID: 30959217 Abstract Title:  Emerging role of air pollution in autoimmune diseases. Abstract:  Autoimmune diseases (ADs) are a broad spectrum of disorders featured by the body's immune responses being directed against its own tissues, resulting in prolonged inflammation and subsequent tissue damage. Recently, the exposure …

Two case reports of life-threatening breakthrough varicella occurring despite vaccination prior to cancer diagnosis, with one resulting in death.

PMID:  Pediatr Infect Dis J. 2015 Sep ;34(9):1027-9. PMID: 25955833 Abstract Title:  Failure of a Single Varicella Vaccination to Protect Children With Cancer From Life-Threatening Breakthrough Varicella. Abstract:  We report 2 children with life-threatening breakthrough varicella. Both had received 1 varicella vaccination before onset of cancer. Despite treatment with intravenous acyclovir, 1 child died of …

Parental PM2.5 exposure-promoted development of metabolic syndrome in offspring.

PMID:  Toxicol Sci. 2019 Aug 1 ;170(2):415-426. PMID: 31086988 Abstract Title:  Parental PM2.5 Exposure-Promoted Development of Metabolic Syndrome in Offspring Is Associated With the Changes of Immune Microenvironment. Abstract:  Parental exposure to ambient fine particulate matter (PM2.5) has been associated with some of adverse health outcomes in offspring. The association between parental PM2.5 exposure and …

There is not enough experience on vaccines in Europe to draw clear conclusions on benefits. It is also not clear what role varicella immunization may play in shingles incidence.

PMID:  Vaccine. 2015 May 15 ;33(21):2406-13. Epub 2015 Apr 1. PMID: 25839105 Abstract Title:  Varicella in Europe-A review of the epidemiology and experience with vaccination. Abstract:  There is no consensus as regards the European varicella immunisation policy; some countries have introduced varicella vaccination in their routine childhood immunisation programs whereas others have decided against or …

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