The immunomodulatory potential of selected bioactive plant-based compounds in breast cancer.

PMID:  Anticancer Agents Med Chem. 2017 ;17(6):770-783. PMID: 27539316 Abstract Title:  The Immunomodulatory Potential of Selected Bioactive Plant-Based Compounds in Breast Cancer: A Review. Abstract:  Breast cancer has continued to cause high cancer death rates among women worldwide. The use of plants' natural products in breast cancer treatment has received more attention in recent years …

Nanoencapsulation, an efficient and promising approach to maximize wound healing efficacy of curcumin.

PMID:  Colloids Surf B Biointerfaces. 2017 Feb 1 ;150:223-241. Epub 2016 Nov 30. PMID: 27918967 Abstract Title:  Nanoencapsulation, an efficient and promising approach to maximize wound healing efficacy of curcumin: A review of new trends and state-of-the-art. Abstract:  Wound healing is a multifarious and vibrant process of replacing devitalized and damaged cellular structures, leading to …

Curcumin inhibiting Th17 cell differentiation by regulating the metabotropic glutamate receptor-4 expression on dendritic cells.

PMID:  Int Immunopharmacol. 2017 May ;46:80-86. PMID: 28273557 Abstract Title:  Curcumin inhibiting Th17 cell differentiation by regulating the metabotropic glutamate receptor-4 expression on dendritic cells. Abstract:  Th17 cells have been categorized as a new lineage of CD4+ T cells, and played a crucial role in the pathogenesis of numerous autoimmune disorders. Type 4 metabotropic glutamate …

Effect of berberine on atherosclerosis and gut microbiota modulation and their correlation in high-fat diet-fed ApoE-/- mice.

PMID:  Front Pharmacol. 2020 ;11:223. Epub 2020 Mar 13. PMID: 32231564 Abstract Title:  Effect of Berberine on Atherosclerosis and Gut Microbiota Modulation and Their Correlation in High-Fat Diet-Fed ApoE-/- Mice. Abstract:  Atherosclerosis and its associated cardiovascular diseases (CVDs) are serious threats to human health and have been reported to be associated with the gut microbiota. …

Role of a berberine-based nutritional supplement in reducing diarrhea in subjects with functional gastrointestinal disorders.

PMID:  Minerva Gastroenterol Dietol. 2020 Mar ;66(1):29-34. PMID: 32283882 Abstract Title:  Role of a berberine-based nutritional supplement in reducing diarrhea in subjects with functional gastrointestinal disorders. Abstract:  BACKGROUND: Berberine, an alkaloid obtained by extraction from Berberis spp., is a botanical that is widely used in the nutraceutical sector to control cholesterol and blood glucose levels. …

Berberine protects against simulated ischemia/reperfusion injury-induced H9C2 cardiomyocytes apoptosis.

PMID:  Front Pharmacol. 2020 ;11:367. Epub 2020 Mar 27. PMID: 32292345 Abstract Title:  Berberine Protects Against Simulated Ischemia/Reperfusion Injury-Induced H9C2 Cardiomyocytes Apoptosisand Myocardial Ischemia/Reperfusion-Induced Apoptosisby Regulating the Mitophagy-Mediated HIF-1α/BNIP3 Pathway. Abstract:  Berberine (BBR) has a variety of pharmacological activities and is widely used in Asian countries. However, the clinical application of BBR still lacks scientific …

Berberine ameliorates prenatal dihydrotestosterone exposure-induced autism-like behaviour by suppression of androgen receptor.

PMID:  Front Cell Neurosci. 2020 ;14:87. Epub 2020 Apr 9. PMID: 32327976 Abstract Title:  Berberine Ameliorates Prenatal Dihydrotestosterone Exposure-Induced Autism-Like Behavior by Suppression of Androgen Receptor. Abstract:  Many epidemiology studies have shown that maternal polycystic ovary syndrome (PCOS) results in a greater risk of autism spectrum disorders (ASD) development, although the detailed mechanism remains unclear. …

Berberine exerted anticancer effects on human gastric cancer both in vitro and in vivo.

PMID:  Evid Based Complement Alternat Med. 2020 ;2020:6195050. Epub 2020 Apr 8. PMID: 32328135 Abstract Title:  Berberine Suppressed Tumor Growth through Regulating Fatty Acid Metabolism and Triggering Cell Apoptosis via Targeting FABPs. Abstract:  Aim: To further investigate the mechanism behind the antitumor properties of berberine regarding lipid metabolism.Methods: Cell viability, proliferation, and apoptosis assays were …

The effect of Berberine on weight loss in order to prevent obesity: A systematic review.

PMID:  Biomed Pharmacother. 2020 Apr 27 ;127:110137. Epub 2020 Apr 27. PMID: 32353823 Abstract Title:  The effect of Berberine on weight loss in order to prevent obesity: A systematic review. Abstract:  This study provides a critical overview of experimental studies in vitro, in humans, and in animals that evaluated the efficacy of Berberine and its …

Berberine inhibits free fatty acid and LPS-induced inflammation via modulating ER stress response in macrophages and hepatocytes.

PMID:  PLoS One. 2020 ;15(5):e0232630. Epub 2020 May 1. PMID: 32357187 Abstract Title:  Berberine inhibits free fatty acid and LPS-induced inflammation via modulating ER stress response in macrophages and hepatocytes. Abstract:  Inflammation plays an essential role in the pathogenesis of non-alcoholic fatty liver disease (NAFLD). Berberine (BBR), an isoquinoline alkaloid isolated from Chinese medicinal herbs, …

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