PMID: Neuropsychiatr Dis Treat. 2019 ;15:2991-3001. Epub 2019 Oct 18. PMID: 31695390 Abstract Title: Stigmasterol Exerts Neuro-Protective Effect Against Ischemic/Reperfusion Injury Through Reduction Of Oxidative Stress And Inactivation Of Autophagy. Abstract: Purpose: Stroke remains the primary cause of pain, suffering, and death in patients. One of the major thrusts in stroke therapy is to find …
Author Archives: Taylor Mercado
Beta-sitosterol treatment attenuates cognitive deficits and prevents amyloid plaque deposition.
PMID: Korean J Physiol Pharmacol. 2020 Jan ;24(1):39-46. Epub 2020 Dec 20. PMID: 31908573 Abstract Title: β-Sitosterol treatment attenuates cognitive deficits and prevents amyloid plaque deposition in amyloid protein precursor/presenilin 1 mice. Abstract: Alzheimer's disease (AD) is the most common neurodegenerative disorder causing dementia worldwide, and is mainly characterized by aggregatedβ-amyloid (Aβ). Increasing evidence has …
β-Sitosterol attenuates carbon tetrachloride-induced oxidative stress and chronic liver injury.
PMID: Naunyn Schmiedebergs Arch Pharmacol. 2020 Jan 13. Epub 2020 Jan 13. PMID: 31930431 Abstract Title: β-Sitosterol attenuates carbon tetrachloride-induced oxidative stress and chronic liver injury in rats. Abstract: Chronic liver diseases are clinically silent and responsible for significant morbidity and mortality worldwide.β-Sitosterol (BSS), major phytosterol in plants, has a wide spectrum of protective effect …
Beta-sitosterol can be used to attenuate pulmonary fibrosis through suppression of EMT by inhibiting the TGF-β1/Snail pathway.
PMID: J Agric Food Chem. 2019 Sep 4 ;67(35):9789-9795. Epub 2019 Aug 19. PMID: 31373816 Abstract Title: Effects ofβ-Sitosterol from Corn Silk on TGF-β1-Induced Epithelial-Mesenchymal Transition in Lung Alveolar Epithelial Cells. Abstract: Pulmonary fibrosis is a chronic lung disease characterized by abnormal accumulation of the extracellular matrix (ECM). Chronic damage of the alveolar epithelium leads …
Corn silk decoction for blood lipid in patients with angina pectoris: A systematic review and meta-analysis.
PMID: Phytother Res. 2019 Nov ;33(11):2862-2869. Epub 2019 Aug 18. PMID: 31423665 Abstract Title: Corn silk decoction for blood lipid in patients with angina pectoris: A systematic review and meta-analysis. Abstract: The aims of this study were to evaluate the efficacy of corn silk decoction on lipid profile in patients with angina pectoris. PubMed, Cochrane, …
Diverse metabolites from corn silk with anti-Aβ1-42 aggregation activity.
PMID: Fitoterapia. 2019 Oct ;138:104356. Epub 2019 Sep 11. PMID: 31520649 Abstract Title: Diverse metabolites from corn silk with anti-Aβaggregation activity. Abstract: Five pairs of enantiomeric compounds (1a/1b-5a/5b) including seven undescribed compounds (1a/1b-3a/3b, 4b) along with two known ones (. and .) have been isolated from corn silk (Stigma maydis). Racemic mixtures of these enantiomers …
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Characterization of a polysaccharide with antioxidant and anti-cervical cancer potentials from the corn silk cultivated in Jilin province.
PMID: Int J Biol Macromol. 2019 Nov 9. Epub 2019 Nov 9. PMID: 31712136 Abstract Title: Characterization of a polysaccharide with antioxidant and anti-cervical cancer potentials from the corn silk cultivated in Jilin province. Abstract: Corn silk polysaccharides (CSPs) were extracted from the corn silk cultivated in Jilin province, China, where is one of the …
Corn silk induced apoptosis in human breast cancer cells.
PMID: Oxid Med Cell Longev. 2019 ;2019:9789241. Epub 2019 Oct 20. PMID: 31781357 Abstract Title: Corn Silk () Induced Apoptosis in Human Breast Cancer (MCF-7) Cells via the ROS-Mediated Mitochondrial Pathway. Abstract: Cancer has been recognized as one of the life-threating diseases. Breast cancer is a leading cause of mortality among women. In spite of …
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Small RNAs in the transgenerational inheritance of epigenetic information.
PMID: Trends Genet. 2020 Jan 14. Epub 2020 Jan 14. PMID: 31952840 Abstract Title: Small RNAs in the Transgenerational Inheritance of Epigenetic Information. Abstract: In recent years it has become evident that RNA interference-related mechanisms can mediate the deposition and transgenerational inheritance of specific chromatin modifications in a truly epigenetic fashion. Rapid progress has been …
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Ultra-processed food consumption may increase exposure to currently used phthalates.
PMID: Environ Int. 2019 10 ;131:105057. Epub 2019 Aug 6. PMID: 31398592 Abstract Title: Ultra-processed food consumption and exposure to phthalates and bisphenols in the US National Health and Nutrition Examination Survey, 2013-2014. Abstract: BACKGROUND: Ultra-processed food has low nutritional quality, is associated with development of chronic diseases, and may increase exposure to chemicals used …
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