Triterpenoids from Ziziphus jujuba induce apoptotic cell death in human cancer cells through mitochondrial reactive oxygen species production.

PMID:  Food Funct. 2018 Jul 17 ;9(7):3895-3905. PMID: 29968885 Abstract Title:  Triterpenoids from Ziziphus jujuba induce apoptotic cell death in human cancer cells through mitochondrial reactive oxygen species production. Abstract:  Ziziphus jujuba var. inermis Rehder is an edible fruit-producing species of the Rhamnaceae family. In the present study, we isolated eight triterpenoids (1-8) from the …

Z. jujuba fruit ethanolic extract possesses antidiarrhoeal and antibacterial activity in a dose depending manner.

PMID:  Open Access Maced J Med Sci. 2018 May 20 ;6(5):757-766. Epub 2018 May 15. PMID: 29875842 Abstract Title:  Anti-Inflammatory, Anti-Bacterial and Anti-Diarrhoeal Activity ofFruit Extract. Abstract:  BACKGROUND: belongs to family Rhamnaceae widely distributed in subtropical and tropical countries. It is used traditionally for several pharmacological purposes including anti-inflammation, antidiarrhoeal and antibacterial, as well as …

Therapeutic potential of natural psychoactive drugs for central nervous system disorders: A perspective from polypharmacology.

PMID:  Curr Med Chem. 2019 Dec 11. Epub 2019 Dec 11. PMID: 31830883 Abstract Title:  Therapeutic potential of natural psychoactive drugs for central nervous system disorders: A perspective from polypharmacology. Abstract:  In drug development, the creation of highly selective ligands has been unsuccessful for the treatment of central nervous system disorders. Multi-target ligands, from the …

Ayahuasca’s ‘afterglow’: improved mindfulness and cognitive flexibility in ayahuasca drinkers.

PMID:  Psychopharmacology (Berl). 2020 Jan 11. Epub 2020 Jan 11. PMID: 31927605 Abstract Title:  Ayahuasca's 'afterglow': improved mindfulness and cognitive flexibility in ayahuasca drinkers. Abstract:  RATIONALE: There is a growing body of evidence demonstrating the therapeutic potential of ayahuasca for treating depression and anxiety. However, the mechanisms of action involved in ayahuasca's therapeutic effects are …

These results suggest that the ceremonial use of ayahuasca has therapeutic value by reducing the severity of grief.

PMID:  Psychopharmacology (Berl). 2020 Jan 14. Epub 2020 Jan 14. PMID: 31938878 Abstract Title:  Therapeutic potential of ayahuasca in grief: a prospective, observational study. Abstract:  RATIONALE: Recent studies have assessed the therapeutic potential of ayahuasca for the treatment of depression with promising preliminary results.OBJECTIVES: Here, we examine the course of grief over 1 year of follow-up …

Zizyphus jujuba and Jujuboside B may have a possible role in the treatment of asthma.

PMID:  Respir Physiol Neurobiol. 2019 02 ;260:28-36. Epub 2018 Dec 3. PMID: 30521862 Abstract Title:  Antiasthmatic potential of Zizyphus jujuba Mill and Jujuboside B. – Possible role in the treatment of asthma. Abstract:  Zizyphus jujuba Mill, a famous oriental traditional medicine, has been reported to exhibit diverse activities in biological systems including the respiratory system. …

Effect of training with or without Jujuba extract on cardiokines in heart tissue of myocardial infarcted rats.

PMID:  Int J Prev Med. 2019 ;10:103. Epub 2019 Jun 7. PMID: 31360350 Abstract Title:  Effect of Training with or without Ziziphus Jujuba Extract on Cardiokines in Heart Tissue of Myocardial Infarcted Rats. Abstract:  Background: Today, the importance of physical activity as a preventative way for cardiovascular disease has attracted much attention.The aim of this …

Therapeutic effects of Ziziphus jujuba Mill. fruit in traditional and modern medicine: a review.

PMID:  Med Chem. 2019 Oct 31. Epub 2019 Oct 31. PMID: 31670624 Abstract Title:  Therapeutic effects of Ziziphus jujuba Mill. fruit in traditional and modern medicine: a review. Abstract:  Ziziphus jujuba Mill. belonging to the Rhamnaceae family, has been consumed since ancient times as a medicine and food. In the different traditional medical schools, Z. …

Ethyl acetate and aqueous fractions of Ziziphus jujuba prevent acute hypertension induced by angiotensin II.

PMID:  Cardiovasc Hematol Disord Drug Targets. 2019 11 19. Epub 2019 Nov 19. PMID: 31746299 Abstract Title:  Ethyl acetate and aqueous fractions of Ziziphus jujuba prevent acute hypertension induced by angiotensin II in rats. Abstract:  BACKGROUND: Antihypertensive effect of Ziziphus jujube (ZJ) has been reported previously.OBJECTIVE: The present study investigates the effect of two ethyl …

Cytoprotective effects of the aqueous extract of the Ziziphus jujuba fruit on TBHP-induced damage on human fibroblast cells.

PMID:  J Basic Clin Physiol Pharmacol. 2019 Nov 22. Epub 2019 Nov 22. PMID: 31756163 Abstract Title:  Cytoprotective effects of the aqueous extract of the Ziziphus jujuba fruit on TBHP-induced damage on human fibroblast cells. Abstract:  Background Oxidative stress plays a major role in the development of various human diseases. However, many antioxidant compounds can …

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