Curcumin chitosan nanocomposite inhibited HCV-4a entry and replication compared to curcumin alone.

PMID:  Int J Nanomedicine. 2020 ;15:2699-2715. Epub 2020 Apr 22. PMID: 32368050 Abstract Title:  Antiviral Activity of Chitosan Nanoparticles Encapsulating Curcumin Against Hepatitis C Virus Genotype 4a in Human Hepatoma Cell Lines. Abstract:  Purpose: Current direct-acting antiviral agents for treatment of hepatitis C virus genotype 4a (HCV-4a) have been reported to cause adverse effects, and therefore …

Epigallocatechin gallate inhibits hepatitis B virus infection in human liver chimeric mice.

PMID:  BMC Complement Altern Med. 2018 Sep 6 ;18(1):248. Epub 2018 Sep 6. PMID: 30189898 Abstract Title:  Epigallocatechin gallate inhibits hepatitis B virus infection in human liver chimeric mice. Abstract:  BACKGROUND: Persistent hepatitis B virus (HBV) infection causes liver cirrhosis and hepatocellular carcinoma and constitutes a major worldwide health problem. Currently, anti-HBV drugs are limited …

This reviewed the current evidences regarding vitamin D role in the pathogenesis and management of different autoimmune diseases.

PMID:  Nutrients. 2020 Mar 17 ;12(3). Epub 2020 Mar 17. PMID: 32192175 Abstract Title:  Pathophysiological Role and Therapeutic Implications of Vitamin D in Autoimmunity: Focus on Chronic Autoimmune Diseases. Abstract:  Vitamin D is a pleiotropic secosteroid yielding multiple actions in human physiology. Besides the canonical regulatory activity on bone metabolism, several non-classical actions have been …

Higher neonatal vitamin D concentration may reduce the risk of developing childhood asthma at ages 3-9 years.

PMID:  Nutrients. 2020 Mar 21 ;12(3). Epub 2020 Mar 21. PMID: 32245170 Abstract Title:  Neonatal Vitamin D Status and Risk of Asthma in Childhood: Results from the D-Tect Study. Abstract:  BACKGROUND: low vitamin D status in pregnancy can influence the offspring's lung function and contribute to childhood asthma development. The objective of this study was …

Addition of selenium improves immunomodulative effects of glucan.

PMID:  N Am J Med Sci. 2016 Feb ;8(2):88-92. PMID: 27042606 Abstract Title:  Addition of Selenium Improves Immunomodulative Effects of Glucan. Abstract:  BACKGROUND: Selenium (Se) is an established essential nutrient that plays a role in various biological processes including cancer development. Similarly, stimulation of immune reactions byβ-glucans is well-documented.AIMS: In the current study, we focused …

The effect of coenzyme Q10 supplementation on oxidative stress.

PMID:  Food Sci Nutr. 2020 Apr ;8(4):1766-1776. Epub 2020 Mar 19. PMID: 32328242 Abstract Title:  The effect of coenzyme Q10 supplementation on oxidative stress: A systematic review and meta-analysis of randomized controlled clinical trials. Abstract:  Some evidence exists in supporting the beneficial effects of coenzyme Q10 (CoQ10) on oxidative stress. Since the findings of studies …

Clinical evidence for Q10 coenzyme supplementation in heart failure.

PMID:  J Clin Med. 2020 Apr 27 ;9(5). Epub 2020 Apr 27. PMID: 32349341 Abstract Title:  Clinical Evidence for Q10 Coenzyme Supplementation in Heart Failure: From Energetics to Functional Improvement. Abstract:  Oxidative stress and mitochondrial dysfunction are hallmarks of heart failure (HF). Coenzyme Q10 (CoQ10) is a vitamin-like organic compound widely expressed in humans as …

The regulation of pathways of inflammation and resolution in immune cells and cancer stem cells by selenium.

PMID:  Adv Cancer Res. 2017 ;136:153-172. Epub 2017 Aug 31. PMID: 29054417 Abstract Title:  The Regulation of Pathways of Inflammation and Resolution in Immune Cells and Cancer Stem Cells by Selenium. Abstract:  Cancer is a complex disease where cancer stem cells (CSCs) maintain unlimited replicative potential, but evade chemotherapy drugs through cellular quiescence. CSCs are …

Cyanocobalamin and cholecalciferol synergistically improve functional and histopathological nerve healing.

PMID:  Ideggyogy Sz. 2020 Mar 30 ;73(3-4):113-120. PMID: 32364338 Abstract Title:  Cyanocobalamin and cholecalciferol synergistically improve functional and histopathological nerve healing in experimental rat model. Abstract:  Background and purpose: Peripheral nerve injury (PNI) is a frequent problem among young adults. Hopefully, regeneration can occur in PNI unlike central nervous system. If nerve cut is complete, …

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