Melatonin supplementation in diabetic diabetic hemodialysis patients had beneficial results.

PMID:  J Ren Nutr. 2019 Oct 6. Epub 2019 Oct 6. PMID: 31597622 Abstract Title:  The Effects of Melatonin Supplementation on Parameters of Mental Health, Glycemic Control, Markers of Cardiometabolic Risk, and Oxidative Stress in Diabetic Hemodialysis Patients: A Randomized, Double-Blind, Placebo-Controlled Trial. Abstract:  OBJECTIVE: This study evaluated the effects of melatonin supplementation on parameters …

Protective effects of melatonin on the skin: future perspectives.

PMID:  Int J Mol Sci. 2019 Oct 8 ;20(19). Epub 2019 Oct 8. PMID: 31597233 Abstract Title:  Protective Effects of Melatonin on the Skin: Future Perspectives. Abstract:  When exposed to hostile environments such as radiation, physical injuries, chemicals, pollution, and microorganisms, the skin requires protective chemical molecules and pathways. Melatonin, a highly conserved ancient molecule, …

Beneficial effect of melatonin on blood loss after cesarean section.

PMID:  J Obstet Gynaecol India. 2019 Oct ;69(5):436-443. Epub 2019 Apr 24. PMID: 31598047 Abstract Title:  Effect of Melatonin on Blood Loss After Cesarean Section: A Prospective Randomized Double-Blind Trial. Abstract:  Background and Objectives: The similarities between the melatonin and oxytocin signaling could lead to increased contractility of myometrium. We designed this randomized double-blind, placebo-controlled …

Melatonin may be a promising therapeutic drug against proliferative vitreoretinopathy.

PMID:  J Pineal Res. 2020 Jan ;68(1):e12615. Epub 2019 Nov 10. PMID: 31605630 Abstract Title:  Melatonin attenuates epidermal growth factor-induced cathepsin S expression in ARPE-19 cells: Implications for proliferative vitreoretinopathy. Abstract:  Abnormal proliferation and motility of retinal pigment epithelial cells leads to proliferative vitreoretinopathy (PVR). Melatonin is a known effective antitumour and anti-invasive agent, but …

Melatonin treatment prevents carbon tetrachloride-induced acute lung injury.

PMID:  Bratisl Lek Listy. 2019 ;120(7):527-531. PMID: 31602989 Abstract Title:  Melatonin treatment prevents carbon tetrachloride-induced acute lung injury in rats by mitigating tissue antioxidant capacity and inflammatory response. Abstract:  AIM: Carbon tetrachloride (CCl4) is an organic chemical that produces different tissue‑damaging effects when ingested or inhaled. Present study aims to determine whether the application of …

Piceatannol inhibits P. acnes-induced keratinocyte proliferation and migration.

PMID:  Inflammation. 2019 Nov 14. Epub 2019 Nov 14. PMID: 31728743 Abstract Title:  Piceatannol Inhibits P. acnes-Induced Keratinocyte Proliferation and Migration by Downregulating Oxidative Stress and the Inflammatory Response. Abstract:  The Cutibacterium acnes (also called Propionibacterium acnes, P. acnes)-induced proliferation and migration of keratinocytes contribute to acne vulgaris (AV), which is a common inflammatory skin …

The present results evidenced the beneficial effects of tannic acid and melatonin in diabetes management.

PMID:  Pak J Pharm Sci. 2019 Jul ;32(4):1453-1459. PMID: 31608862 Abstract Title:  Antidiabetic and antioxidant effects of tannic acid and melatonin on streptozotocin induced diabetes in rats. Abstract:  The present investigation aimed to study the possible antidiabetic and related antioxidant potentials of tannic acid and melatonin in streptozotocin (STZ) induced diabetes in rats. Four groups …

This study found that melatonin and curcumin can be used to quicken neural recovery and help treat nerve injury.

PMID:  EXCLI J. 2019 ;18:653-665. Epub 2019 Aug 21. PMID: 31611748 Abstract Title:  Comparison of melatonin and curcumin effect at the light and dark periods on regeneration of sciatic nerve crush injury in rats. Abstract:  Being one of the acute clinical problems, peripheral nerve injury can bring about a number of consequences including severe disability, …

Perioperative melatonin reduced the incidence of delirium in older adults in the included studies.

PMID:  BMC Geriatr. 2019 Oct 16 ;19(1):272. Epub 2019 Oct 16. PMID: 31619178 Abstract Title:  Melatonin for the prevention of postoperative delirium in older adults: a systematic review and meta-analysis. Abstract:  BACKGROUND: Older surgical patients are at high risk of developing postoperative delirium. Non-pharmacological strategies are recommended for delirium prevention, but no pharmacological agents have …

Melatonin rescued methotrexate-induced spatial deficit and hyperhomocysteinemia.

PMID:  Life Sci. 2019 Oct 13:116931. Epub 2019 Oct 13. PMID: 31618610 Abstract Title:  Melatonin rescued methotrexate-induced spatial deficit and hyperhomocysteinemia and increased asymmetric dimethylarginine in plasma and dorsal hippocampus in developing rats. Abstract:  AIMS: With the improvement of the survival rates in children acute lymphoblastic leukemia (ALL), some children ALL survivors show impaired cognitive …

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