Structural elucidation and immune-enhancing effects of novel polysaccharide from Grifola frondosa.

PMID:  Biomed Res Int. 2019 ;2019:7528609. Epub 2019 Apr 16. PMID: 31139649 Abstract Title:  Structural Elucidation and Immune-Enhancing Effects of Novel Polysaccharide from. Abstract:  Beta-glucan (-glucan) is a macromolecule structure where glucose unit has bonded through-glycosidic bond at 1 and 3 positions. It is well known as a natural immunomodulator without exhibiting any side effects …

Grifola frondosa extract and ergosterol reduce allergic reactions in an allergy mouse model by suppressing the degranulation of mast cells.

PMID:  Biosci Biotechnol Biochem. 2019 Dec ;83(12):2280-2287. Epub 2019 Aug 14. PMID: 31412751 Abstract Title:  extract and ergosterol reduce allergic reactions in an allergy mouse model by suppressing the degranulation of mast cells. Abstract:  The increasing number of patients suffering from allergic diseases is a global health problem.is an edible mushroom consumed as a health …

The positive effects of Grifola frondosa heteropolysaccharide on NAFLD and regulation of the gut microbiota.

PMID:  Int J Mol Sci. 2019 Oct 24 ;20(21). Epub 2019 Oct 24. PMID: 31653116 Abstract Title:  The Positive Effects ofHeteropolysaccharide on NAFLD and Regulation of the Gut Microbiota. Abstract:  Non-alcoholic fatty liver disease (NAFLD) is a major public health problem in many countries. In this study, the ability ofheteropolysaccharide (GFP) to ameliorate NAFLD was …

Synergistic immuno-modulatory activity in human macrophages of a medicinal mushroom formulation consisting of Reishi, Shiitake and Maitake.

PMID:  PLoS One. 2019 ;14(11):e0224740. Epub 2019 Nov 7. PMID: 31697749 Abstract Title:  Synergistic immuno-modulatory activity in human macrophages of a medicinal mushroom formulation consisting of Reishi, Shiitake and Maitake. Abstract:  A key characteristic of mushroom polysaccharides that elicit an immunomodulatory response is that they are rich inβ-glucans and low in α-glucans. In this study …

Hypoglycemic and hypolipidemic activities of Grifola frondosa polysaccharides.

PMID:  Int J Biol Macromol. 2019 Nov 20. Epub 2019 Nov 20. PMID: 31759027 Abstract Title:  Hypoglycemic and hypolipidemic activities of Grifola frondosa polysaccharides and their relationships with the modulation of intestinal microflora in diabetic mice induced by high-fat diet and streptozotocin. Abstract:  This study aimed to investigate the hypoglycemic and hypolipidemic activities of polysaccharides …

A polysaccharide from Grifola frondosa fruit body induces HT-29 cells apoptosis by PI3K/AKT-MAPKs and NF-κB-pathway.

PMID:  Int J Biol Macromol. 2020 Mar 15 ;147:79-88. Epub 2020 Jan 8. PMID: 31923503 Abstract Title:  A polysaccharide from Grifola frondosa fruit body induces HT-29 cells apoptosis by PI3K/AKT-MAPKs and NF-κB-pathway. Abstract:  BACKGROUND: A neutral polysaccharide was isolated from the fruiting body of a mushroom Grifola frondosa (GFP-A). The tumor suppressive activity of GFP-A …

Meta-analysis on effect of Grifola frondosa polysaccharide in regulating in vivo immunoregulatory function.

PMID:  Zhongguo Zhong Yao Za Zhi. 2019 Dec ;44(23):5174-5183. PMID: 32237355 Abstract Title:  [Meta-analysis on effect of Grifola frondosa polysaccharide in regulating in vivo immunoregulatory function on animal disease models]. Abstract:  The study aimed to explore the in vivo immunoregulatory function of Grifola frondosa polysaccharide( GFP) on animal disease models. Databases of PubMed,Embase,Web of Scinece,CNKI,CBM …

Host microRNAs and exosomes that modulate influenza virus infection.

PMID:  Virus Res. 2020 Apr 2 ;279:197885. Epub 2020 Jan 22. PMID: 31981772 Abstract Title:  Host microRNAs and exosomes that modulate influenza virus infection. Abstract:  MicroRNAs (miRNAs) are small non-coding RNAs that post-transcriptionally regulate over half of human protein-coding genes and play a vital role in cellular development, proliferation, metabolism, and homeostasis. Exosomes are rounded …

Human immunodeficiency virus-associated exosomes promote Kaposi’s sarcoma-associated herpesvirus infection.

PMID:  J Virol. 2020 Apr 16 ;94(9). Epub 2020 Apr 16. PMID: 32051269 Abstract Title:  Human Immunodeficiency Virus-Associated Exosomes Promote Kaposi's Sarcoma-Associated Herpesvirus Infection via the Epidermal Growth Factor Receptor. Abstract:  Kaposi's sarcoma-associated herpesvirus (KSHV) is the causal agent for Kaposi's sarcoma (KS), the most common malignancy in people living with human immunodeficiency virus (HIV)/AIDS. …

Astragaloside IV attenuates IL-1β secretion by enhancing autophagy in H1N1 infection.

PMID:  FEMS Microbiol Lett. 2020 Feb 1 ;367(4). PMID: 32108899 Abstract Title:  Astragaloside IV attenuates IL-1β secretion by enhancing autophagy in H1N1 infection. Abstract:  Excessive secretion of inflammatory factors (cytokine storm) plays a significant role in H1N1-induced acute pneumonia, and autophagy acts as a cell-intrinsic mechanism to regulate inflammation. Astragaloside IV (AS-IV), originating from the …

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