PMID: Influenza Other Respir Viruses. 2017 09 ;11(5):457-463. Epub 2017 Jul 11. PMID: 28646616 Abstract Title: Curcumin alleviates macrophage activation and lung inflammation induced by influenza virus infection through inhibiting the NF-κB signaling pathway. Abstract: BACKGROUND: Influenza A viruses (IAV) result in severe public health problems with worldwide each year. Overresponse of immune system to …
Author Archives: Taylor Mercado
Curcumin ameliorates asthmatic airway inflammation.
PMID: Clin Exp Pharmacol Physiol. 2015 May ;42(5):520-9. PMID: 25739561 Abstract Title: Curcumin ameliorates asthmatic airway inflammation by activating nuclear factor-E2-related factor 2/haem oxygenase (HO)-1 signalling pathway. Abstract: Previous studies have shown that curcumin alleviates asthma in vivo. However, the relationship between curcumin and the nuclear factor-E2-related factor 2 (Nrf2)/haem oxygenase (HO)-1 pathway in asthma …
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Emodin alleviated LPS-induced pulmonary inflammation in rat lung tissues.
PMID: Inflamm Res. 2020 Apr ;69(4):365-373. Epub 2020 Mar 4. PMID: 32130427 Abstract Title: Emodin alleviated pulmonary inflammation in rats with LPS-induced acute lung injury through inhibiting the mTOR/HIF-1α/VEGF signaling pathway. Abstract: OBJECTIVE AND DESIGN: This study aimed to investigate the anti-pulmonary inflammation effect of emodin on Wistar rats with lipopolysaccharide (LPS)-induced acute lung injury …
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Aloe-emodin induces breast tumor cell apoptosis.
PMID: Evid Based Complement Alternat Med. 2020 ;2020:5108298. Epub 2020 Mar 3. PMID: 32190086 Abstract Title: Aloe-Emodin Induces Breast Tumor Cell Apoptosis through Upregulation of miR-15a/miR-16-1 That Suppresses BCL2. Abstract: Purpose: Aloe-emodin (AE) is a natural compound derived from aloe vera and palmatum rhubarb and shows anticancer activities in various cancers. Bcl-2 family is the …
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Aloe-emodin exerts cholesterol-lowering effects by inhibiting proprotein convertase subtilisin/kexin type 9.
PMID: Acta Pharmacol Sin. 2020 Mar 18. Epub 2020 Mar 18. PMID: 32203084 Abstract Title: Aloe-emodin exerts cholesterol-lowering effects by inhibiting proprotein convertase subtilisin/kexin type 9 in hyperlipidemic rats. Abstract: Hyperlipidemia (HPL) characterized by metabolic disorder of lipids and cholesterol is one of the important risk factors for cardiovascular diseases. Proprotein convertase subtilisin/kexin type 9 …
Aloe emodin inhibits telomerase activity in breast cancer cells: transcriptional and enzymological mechanism.
PMID: Pharmacol Rep. 2020 Mar 23. Epub 2020 Mar 23. PMID: 32207090 Abstract Title: Aloe emodin inhibits telomerase activity in breast cancer cells: transcriptional and enzymological mechanism. Abstract: BACKGROUND: Telomerase plays an essential role in cancer cell proliferation. In this study, we investigated inhibition mechanism of aloe emodin (AE) on three different types of breast …
Inhibition of curcumin on influenza A virus infection and influenzal pneumonia.
PMID: Int Immunopharmacol. 2018 Jan ;54:177-187. Epub 2017 Nov 15. PMID: 29153953 Abstract Title: Inhibition of curcumin on influenza A virus infection and influenzal pneumonia via oxidative stress, TLR2/4, p38/JNK MAPK and NF-κB pathways. Abstract: Oxidative stress, Nrf2-HO-1 and TLR-MAPK/NF-κB signaling pathways have been proved to be involved in influenza A virus (IAV) replication and …
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Curcumin ameliorates severe influenza pneumonia via attenuating lung injury and regulating macrophage cytokines production.
PMID: Clin Exp Pharmacol Physiol. 2018 Jan ;45(1):84-93. Epub 2017 Oct 3. PMID: 28853207 Abstract Title: Curcumin ameliorates severe influenza pneumonia via attenuating lung injury and regulating macrophage cytokines production. Abstract: Curcumin, an active phenolic agent extract from the Curcuma longa, exhibits excellent anti-cancer, anti-inflammation, and neuroprotective effects. We aimed to investigate the anti-influenza role …
Anti-tumor bioactivities of curcumin on mice loaded with gastric carcinoma.
PMID: Food Funct. 2017 Sep 20 ;8(9):3319-3326. PMID: 28848967 Abstract Title: Anti-tumor bioactivities of curcumin on mice loaded with gastric carcinoma. Abstract: Curcumin, a derivative from the dried rhizome of curcuma longa, has been proven to possess anti-tumor effects. However, the detailed molecular mechanisms have not been fully elucidated. In this study, we aimed to …
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Effects of water extract of Curcuma longa roots on immunity and telomerase function.
PMID: J Complement Integr Med. 2017 May 12 ;14(3). Epub 2017 May 12. PMID: 28889732 Abstract Title: Effects of water extract of Curcuma longa (L.) roots on immunity and telomerase function. Abstract: Background Immunity and Longevity Methods A water extract of Curcuma longa (L.) [vern. Turmeric] roots (TurmericImmune™) standardized for a minimum 20 % of turmeric …
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