PMID: Molecules. 2018 Jan 18 ;23(1). Epub 2018 Jan 18. PMID: 29346317 Abstract Title: Liposomal TriCurin, A Synergistic Combination of Curcumin, Epicatechin Gallate and Resveratrol, Repolarizes Tumor-Associated Microglia/Macrophages, and Eliminates Glioblastoma (GBM) and GBM Stem Cells. Abstract: Glioblastoma (GBM) is a deadly brain tumor with a current mean survival of 12-15 months. Despite being a …
Author Archives: Taylor Mercado
Curcuminoids from Curcuma Longa: New adjuvants for the treatment of crohn’s disease and ulcerative colitis?
PMID: Crit Rev Food Sci Nutr. 2019 ;59(13):2136-2143. Epub 2018 Apr 12. PMID: 29565637 Abstract Title: Curcuminoids from: New adjuvants for the treatment of crohn's disease and ulcerative colitis? Abstract: Crohn's Disease (CD) and Ulcerative Colitis (UC) result from an overreaction of the bowel to multifactorial stimuli leading to discomfort, pain, and it is associated …
Selenium alleviates apoptosis induced by fluoride through improving the expression of HSP70 and reduces oxidative stress.
PMID: Eur J Pharmacol. 2020 Apr 8 ;878:173098. Epub 2020 Apr 8. PMID: 32275908 Abstract Title: Selenium may suppress peripheral blood mononuclear cell apoptosis by modulating HSP70 and regulate levels of SIRT1 through reproductive hormone secretion and oxidant stress in women suffering fluorosis. Abstract: Excessive taking fluoride (F) causes severe damage to reproductive system through …
Fish oil consumption may play an important role in modulating microglial/macrophage response and ameliorating the Alzheimer’s disease pathology.
PMID: PLoS One. 2019 ;14(5):e0216726. Epub 2019 May 16. PMID: 31095617 Abstract Title: Short-term fish oil supplementation applied in presymptomatic stage of Alzheimer's disease enhances microglial/macrophage barrier and prevents neuritic dystrophy in parietal cortex of 5xFAD mouse model. Abstract: Dystrophic neurites and activated microglia are one of the main neuropathological characteristics of Alzheimer's disease (AD). …
Dendritic cells mediate the anti-inflammatory action of omega-3 long-chain polyunsaturated fatty acids in experimental autoimmune uveitis.
PMID: PLoS One. 2019 ;14(7):e0219405. Epub 2019 Jul 23. PMID: 31335861 Abstract Title: Dendritic cells mediate the anti-inflammatory action of omega-3 long-chain polyunsaturated fatty acids in experimental autoimmune uveitis. Abstract: We previously showed that dietary omega (ω)-3 long-chain polyunsaturated fatty acids (LCPUFAs) suppress inflammation in mice with experimental autoimmune uveitis (EAU). We have now investigated …
Effects of fish n-3 PUFAs on intestinal microbiota and immune system.
PMID: Mar Drugs. 2019 Jun 22 ;17(6). Epub 2019 Jun 22. PMID: 31234533 Abstract Title: Effects of Fish n-3 PUFAs on Intestinal Microbiota and Immune System. Abstract: Studies over several decades have documented the beneficial actions of n-3 polyunsaturated fatty acids (PUFAs), which are plentiful in fish oil, in different disease states. Mechanisms responsible for …
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n-3 PUFAs attenuated anti-viral CD8+ T cell responses against acute viral infection and could be used to alleviate immunopathology mediated by viral infection.
PMID: Int J Mol Sci. 2019 Sep 12 ;20(18). Epub 2019 Sep 12. PMID: 31547227 Abstract Title: Endogenous-3 Polyunsaturated Fatty Acids Are Beneficial to Dampen CD8T Cell-Mediated Inflammatory Response upon the Viral Infection in Mice. Abstract: Omega-3 (-3) polyunsaturated fatty acids (PUFAs) have been known to exert anti-inflammatory effects on various disease states. However, its …
Depressed Cancer Survivors Have Increased Risk of Death, Opioid Use
Mental health conditions may not only increase opioid use but also risk of death. Learn how this common pain medication may become deadly when you’re depressed
Krill oil might be a new candidate for treatment of iron overload-induced toxicity.
PMID: Environ Sci Pollut Res Int. 2020 Feb ;27(4):3950-3961. Epub 2019 Dec 10. PMID: 31823254 Abstract Title: Krill oil alleviates oxidative stress, iron accumulation and fibrosis in the liver and spleen of iron-overload rats. Abstract: Krill oil (KO) is a recent supplement which is rich in eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA). These fatty …
Daily meal supplemented with astaxanthin-enriched yolk has mitigative effects against hypertension.
PMID: Biol Pharm Bull. 2020 ;43(3):404-408. PMID: 32115501 Abstract Title: Daily Meal Supplemented with Astaxanthin-Enriched Yolk Has Mitigative Effects against Hypertension in Spontaneously Hypertensive Rats. Abstract: The aim of this study was to investigate the effects of egg yolk powder enriched with astaxanthin (ASX-E) on blood pressure in spontaneously hypertensive rats (SHR) and to verify …
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