Taylor Mercado

Molecular mechanisms of curcumin in neuroinflammatory disorders.

n/a PMID: Endocr Metab Immune Disord Drug Targets. 2019 ;19(3):247-258. PMID: 30488803 Abstract Title: Molecular Mechanisms of Curcumin in Neuroinflammatory Disorders: A Mini Review of Current Evidences. Abstract: OBJECTIVE: Neuroinflammatory disease is a general term used to denote the progressive loss of neuronal function or structure. Many neuroinflammatory diseases, including Alzheimer's, Parkinson's, and multiple sclerosis …

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Mechanistic insights of hepatoprotective effects of curcumin.

PMID: Food Chem Toxicol. 2019 Feb ;124:182-191. Epub 2018 Dec 5. PMID: 30529260 Abstract Title: Mechanistic insights of hepatoprotective effects of curcumin: Therapeutic updates and future prospects. Abstract: The liver is the most essential organ of the body performing vital functions. Hepatic disorders affect the physiological and biochemical functions of the body. These disorders include …

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Curcumin as a therapeutic candidate for multiple sclerosis: Molecular mechanisms and targets.

PMID: J Cell Physiol. 2019 08 ;234(8):12237-12248. Epub 2018 Dec 10. PMID: 30536381 Abstract Title: Curcumin as a therapeutic candidate for multiple sclerosis: Molecular mechanisms and targets. Abstract: Multiple sclerosis (MS) is a disease that has shown a considerable increase in prevalence in recent centuries. Current knowledge about its etiology is incomplete, and therefore it …

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These findings indicate that combination therapy of ω-3 fatty acids and nano-curcumin can be considered as a promising new approach in migraine prevention.

PMID: Endocr Metab Immune Disord Drug Targets. 2019 ;19(6):874-884. PMID: 30760195 Abstract Title: The Neuromodulatory Effects ofω-3 Fatty Acids and Nano-Curcumin on the COX-2/ iNOS Network in Migraines: A Clinical Trial Study from Gene Expression to Clinical Symptoms. Abstract: BACKGROUND: Migraine is a common neuroinflammatory disorder characterized by recurrent attacks of pain. Human and experimental …

Continue reading “These findings indicate that combination therapy of ω-3 fatty acids and nano-curcumin can be considered as a promising new approach in migraine prevention.”

Effects of curcumin on microglial cells.

PMID: Neurotox Res. 2019 Jul ;36(1):12-26. Epub 2019 Apr 4. PMID: 30949950 Abstract Title: Effects of Curcumin on Microglial Cells. Abstract: Microglia are innate immune system cells which reside in the central nervous system (CNS). Resting microglia regulate the homeostasis of the CNS via phagocytic activity to clear pathogens and cell debris. Sometimes, however, to …

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Curcumin attenuates oxidative stress in RAW264.7 cells by increasing the activity of antioxidant enzymes and activating the Nrf2-Keap1 pathway.

PMID: PLoS One. 2019 ;14(5):e0216711. Epub 2019 May 21. PMID: 31112588 Abstract Title: Curcumin attenuates oxidative stress in RAW264.7 cells by increasing the activity of antioxidant enzymes and activating the Nrf2-Keap1 pathway. Abstract: Large-scale breeding environments often lead to oxidative stress. Macrophages play an important role in the immune system and are vulnerable to reactive …

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Targeting regulatory T cells by curcumin: A potential for cancer immunotherapy.

PMID: Pharmacol Res. 2019 09 ;147:104353. Epub 2019 Jul 12. PMID: 31306775 Abstract Title: Targeting regulatory T cells by curcumin: A potential for cancer immunotherapy. Abstract: Immune system has critical roles in fighting against several diseases like cancer. Cancer cells evolve several ways to escape from the immune system to remain alive and trigger new …

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The effect of oral consumption of propolis alone and in combination with silver nanoparticles on wound healing.

PMID: Wound Manag Prev. 2020 04 ;66(4):38-46. PMID: 32294058 Abstract Title: The Effect of Oral Consumption of Propolis Alone and in Combination With Silver Nanoparticles on Wound Healing in Male Wistar Rats. Abstract: : Research to identify and develop compounds that facilitate wound healing is important, especially for hard-to-heal chronic wounds.PURPOSE: This study was conducted …

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Biogenic silver nanoparticles: in vitro and in vivo antitumor activity in bladder cancer.

PMID: Eur J Pharm Biopharm. 2020 Apr 17. Epub 2020 Apr 17. PMID: 32311428 Abstract Title: Biogenic silver nanoparticles: in vitro and in vivo antitumor activity in bladder cancer. Abstract: ladder cancer is the fifth most common disease in the United States, and the treatment and alternatives for patients have not changed in the last …

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The review concludes the results of recent studies on Ashwagandha suggesting its extensive potential as neuroprotective in various brain disorders.

PMID: J Ethnopharmacol. 2020 Apr 16 ;257:112876. Epub 2020 Apr 16. PMID: 32305638 Abstract Title: Ashwagandha in brain disorders: A review of recent developments. Abstract: ETHNOPHARMACOLOGICAL RELEVANCE: Withania somnifera (Family: Solanaceae), commonly known as Ashwagandha or Indian ginseng is distributed widely in India, Nepal, China and Yemen. The roots of plant consist of active phytoconstituents …

Continue reading “The review concludes the results of recent studies on Ashwagandha suggesting its extensive potential as neuroprotective in various brain disorders.”