The β-sitosterol-mediated cardioprotective effects may involve the modulation of PPARγ/NF-κB signalling during myocardial I/R injury.

PMID:  Evid Based Complement Alternat Med. 2020 ;2020:2679409. Epub 2020 Mar 28. PMID: 32308701 Abstract Title:  -Sitosterol Protects against Myocardial Ischemia/Reperfusion Injury via Targeting PPAR/NF-B Signalling. Abstract:  Myocardial ischemia/reperfusion (I/R) injury is a clinically severe complication, which can cause high rates of disability and mortality particularly in patients with myocardial infarction, yet the molecular mechanisms …

β-sitosterol assisted silver nanoparticles activates Nrf2 and triggers mitochondrial apoptosis via oxidative stress in human hepatocellular cancer cell line.

PMID:  J Biomed Mater Res A. 2020 Apr 21. Epub 2020 Apr 21. PMID: 32319188 Abstract Title:  β-sitosterol assisted silver nanoparticles activates Nrf2 and triggers mitochondrial apoptosis via oxidative stress in human hepatocellular cancer cell line. Abstract:  Cancer nanomedicine is an emerging field of cancer therapeutics. Incidence of hepatocellular carcinoma is increasing worldwide and currently, …

Antimicrobial activity of silver-treated bacteria against other multi-drug resistant pathogens in their environment.

PMID:  Antibiotics (Basel). 2020 Apr 15 ;9(4). Epub 2020 Apr 15. PMID: 32326384 Abstract Title:  Antimicrobial Activity of Silver-Treated Bacteria against other Multi-Drug Resistant Pathogens in Their Environment. Abstract:  Silver is a potent antimicrobial agent against a variety of microorganisms and once the element has entered the bacterial cell, it accumulates as silver nanoparticles with …

Efficacy of a Peruvian botanical remedy (Sabell A4+) for treating liver disease and protecting gastric mucosal integrity.

PMID:  Evid Based Complement Alternat Med. 2019 ;2019:5486728. Epub 2019 Oct 24. PMID: 31781272 Abstract Title:  Efficacy of a Peruvian Botanical Remedy (Sabell A4+) for Treating Liver Disease and Protecting Gastric Mucosal Integrity. Abstract:  The purpose of this study was to determine the efficacy of a Peruvian botanical formulation for treating disorders of hepatic function …

Curcumin as an ajuvant treatment of depression: mechanisms of action and application prospects.

PMID:  Zh Nevrol Psikhiatr Im S S Korsakova. 2020 ;120(2):125-131. PMID: 32307422 Abstract Title:  [Curcumin as an ajuvant treatment of depression: mechanisms of action and application prospects]. Abstract:  Curcumin, a natural compound found in the rhizomes of turmeric, has a pronounced anti-inflammatory activity. Rodent models of depression show that this activity is similar to the …

Anti-H1N1 viral activity of three main active ingredients from zedoary oil.

PMID:  Fitoterapia. 2020 Apr ;142:104489. Epub 2020 Jan 28. PMID: 32004654 Abstract Title:  Anti-H1N1 viral activity of three main active ingredients from zedoary oil. Abstract:  Influenza virus is one of the most widespread infectious diseases in the world. It poses a serious public health threat to humans. With the emergence of drug-resistant virus strains, antiviral …

Curcumol attenuates liver sinusoidal endothelial cell angiogenesis via regulating Glis-PROX1-HIF-1α in liver fibrosis.

PMID:  Cell Prolif. 2020 Mar ;53(3):e12762. Epub 2020 Mar 2. PMID: 32119185 Abstract Title:  Curcumol attenuates liver sinusoidal endothelial cell angiogenesis via regulating Glis-PROX1-HIF-1α in liver fibrosis. Abstract:  OBJECTIVE: Hepatic sinusoidal angiogenesis owing to dysfunctional liver sinusoidal endothelial cells (LSECs) accompanied by an abnormal angioarchitecture is a symbol related to liver fibrogenesis, which indicates a …

Curcumol inhibits the proliferation and metastasis of melanoma.

PMID:  J Cancer. 2020 ;11(7):1679-1692. Epub 2020 Jan 14. PMID: 32194780 Abstract Title:  Curcumol inhibits the proliferation and metastasis of melanoma via the miR-152-3p/PI3K/AKT and ERK/NF-κB signaling pathways. Abstract:  Melanoma is the most aggressive and treatment-resistant form of skin cancer. Curcumol is a Chinese medicinal herb traditionally used as a cancer remedy. However, the molecular …

Curcumol might represent a promising lead compound for the development of new targeted anti-cancer therapeutics.

PMID:  J Ethnopharmacol. 2020 Apr 9 ;257:112835. Epub 2020 Apr 9. PMID: 32278762 Abstract Title:  Curcumol inhibits the expression of programmed cell death-ligand 1 through crosstalk between hypoxia-inducible factor-1α and STAT3 (T705) signaling pathways in hepatic cancer. Abstract:  ETHNOPHARMACOLOGICAL RELEVANCE: Curcuma wenyujin is a Chinese traditional herbal medicine that is commonly used as an anti-oxidant, …

Gender differences in plasma vitamin C concentrations and cognitive function.

PMID:  Curr Dev Nutr. 2020 Apr ;4(4):nzaa038. Epub 2020 Mar 18. PMID: 32337476 Abstract Title:  Gender Differences in Plasma Vitamin C Concentrations and Cognitive Function: A Pilot Cross-Sectional Study in Healthy Adults. Abstract:  Background: A number of investigations have highlighted the importance of vitamin C in maintaining brain health. Biologically, vitamin C has exhibited roles …

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