Bisdemethoxycurcumin enhances the sensitivity of non-small cell lung cancer cells to icotinib.

PMID:  Int J Biol Sci. 2020 ;16(9):1536-1550. Epub 2020 Mar 5. PMID: 32226300 Abstract Title:  Bisdemethoxycurcumin Enhances the Sensitivity of Non-small Cell Lung Cancer Cells to Icotinib via Dual Induction of Autophagy and Apoptosis. Abstract:  Non-small cell lung cancer (NSCLC) with epidermal growth factor receptor (EGFR) wild-type is intrinsic resistance to EGFR-tyrosine kinase inhibitors (TKIs). …

Antifungal activity of zedoary turmeric oil against Phytophthora capsici through damaging cell membrane.

PMID:  Pestic Biochem Physiol. 2019 Sep ;159:59-67. Epub 2019 May 24. PMID: 31400785 Abstract Title:  Antifungal activity of zedoary turmeric oil against Phytophthora capsici through damaging cell membrane. Abstract:  Phytophthora capsici is a plant oomycete pathogen, which causes many devastating diseases on a broad range of hosts. Zedoary turmeric oil (ZTO) is a kind of …

An overview of the therapeutic effects of curcumol in several diseases.

PMID:  Nutr Cancer. 2020 Apr 14:1-15. Epub 2020 Apr 14. PMID: 32285707 Abstract Title:  Therapeutic Effects of Curcumol in Several Diseases; An Overview. Abstract:  also known asis a traditional Chinese medicine that has been used for many centuries against several diseases. The rhizome of the plant is composed of curcuminoids (curcumin, demethoxycurcumin, and bisdemethoxycurcumin), and …

β-Elemene inhibits the metastasis of multidrug-resistant gastric cancer cells through miR-1323/Cbl-b/EGFR pathway.

PMID:  Phytomedicine. 2020 Feb 10 ;69:153184. Epub 2020 Feb 10. PMID: 32199253 Abstract Title:  β-Elemene inhibits the metastasis of multidrug-resistant gastric cancer cells through miR-1323/Cbl-b/EGFR pathway. Abstract:  BACKGROUND: β-Elemene is a natural agent extracted from the traditional Chinese herbal medicine Curcuma wenyujin that is a promising novel plant-derived drug with broad-spectrum anticancer activity. Our previous …

β-elemene suppresses the malignant behavior of esophageal cancer cells by regulating the phosphorylation of AKT.

PMID:  Acta Histochem. 2020 Mar 14:151538. Epub 2020 Mar 14. PMID: 32183989 Abstract Title:  β-elemene suppresses the malignant behavior of esophageal cancer cells by regulating the phosphorylation of AKT. Abstract:  BACKGROUND: Esophageal cancer is a digestive tract malignancy, ranking sixth among the world's deadliest tumor incidence. However, the pathogenesis of esophageal cancer is complex and …

The antitumor efficacy of β-elemene by changing tumor inflammatory environment and tumor microenvironment

PMID:  Biomed Res Int. 2020 ;2020:6892961. Epub 2020 Feb 19. PMID: 32149121 Abstract Title:  The Antitumor Efficacy of-Elemene by Changing Tumor Inflammatory Environment and Tumor Microenvironment. Abstract:  Inflammatory mediators and inflammatory cells in the inflammatory microenvironment promote the transformation of normal cells to cancer cells in the early stage of cancer, promote the growth and …

The emerging role of curcumin in the modulation of TLR-4 signaling pathway.

PMID:  Int J Mol Sci. 2020 Mar 26 ;21(7). Epub 2020 Mar 26. PMID: 32225104 Abstract Title:  The Emerging Role of Curcumin in the Modulation of TLR-4 Signaling Pathway: Focus on Neuroprotective and Anti-Rheumatic Properties. Abstract:  Natural products have been used in medicine for thousands of years. Given their potential health benefits, they have gained …

Allium hookeri root extract regulates asthmatic changes through immunological modulation of Th1/Th2‑related factors in an ovalbumin‑induced asthma.

PMID:  Mol Med Rep. 2019 Oct ;20(4):3215-3223. Epub 2019 Aug 6. PMID: 31432168 Abstract Title:  Allium hookeri root extract regulates asthmatic changes through immunological modulation of Th1/Th2‑related factors in an ovalbumin‑induced asthma mouse model. Abstract:  In 2013, WHO estimated that approximately 235 million people suffered from asthma worldwide. Asthma is a hyper responsive disorder, which is related …

Allium hookeri root extract inhibits adipogenesis by promoting lipolysis in high fat diet-induced obese mice.

PMID:  Nutrients. 2019 Sep 20 ;11(10). Epub 2019 Sep 20. PMID: 31547031 Abstract Title:  Root Extract Inhibits Adipogenesis by Promoting Lipolysis in High Fat Diet-Induced Obese Mice. Abstract:  (AH) is widely consumed as a herbal medicine. It possesses biological activity against metabolic diseases. The objective of this study was to investigate effects of AH root …

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