Immunomodulatory effects of glutathione, garlic derivatives, and hydrogen sulfide.

PMID:  Nutrients. 2019 Jan 30 ;11(2). Epub 2019 Jan 30. PMID: 30704060 Abstract Title:  Immunomodulatory Effects of Glutathione, Garlic Derivatives, and Hydrogen Sulfide. Abstract:  Glutathione and aged garlic extract are sulfur-containing products that play important protective and regulatory roles within the immune system and in oxidative processes. Hydrogen sulfide (H₂S), an endogenous, gaseous, signaling transmitter, …

Alliin alters gut microbiota and gene expression of colonic epithelial tissues.

PMID:  J Food Biochem. 2019 Apr ;43(4):e12795. Epub 2019 Feb 21. PMID: 31353605 Abstract Title:  Alliin alters gut microbiota and gene expression of colonic epithelial tissues. Abstract:  Alliin is a natural organosulfur-containing phytochemical in garlic. It is possible that alliin can regulate the gut microbiota for its strong antimicrobial activity against many pathogens. Here, we …

Carnosol inhibits inflammasome activation by directly targeting HSP90 to treat inflammasome-mediated diseases

PMID:  Cell Death Dis. 2020 Apr 20 ;11(4):252. Epub 2020 Apr 20. PMID: 32312957 Abstract Title:  Carnosol inhibits inflammasome activation by directly targeting HSP90 to treat inflammasome-mediated diseases. Abstract:  Aberrant activation of inflammasomes, a group of protein complexes, is pathogenic in a variety of metabolic and inflammation-related diseases. Here, we report that carnosol inhibits NLRP3 …

Attenuation of allergen-mediated mast cell activation by rosemary extract (Rosmarinus officinalis L.).

PMID:  J Leukoc Biol. 2020 Mar 23. Epub 2020 Mar 23. PMID: 32202360 Abstract Title:  Attenuation of allergen-mediated mast cell activation by rosemary extract (Rosmarinus officinalis L.). Abstract:  Mast cells are immune sentinels and a driving force in both normal and pathological contexts of inflammation, with a prominent role in allergic hypersensitivities. Crosslinking of FcεRI …

Protective effects of carnosic acid on retinal ganglion cells in acute ocular hypertension rats.

PMID:  Int Ophthalmol. 2020 Apr 10. Epub 2020 Apr 10. PMID: 32277323 Abstract Title:  Protective effects of carnosic acid on retinal ganglion cells in acute ocular hypertension rats. Abstract:  OBJECTIVE: To observe the protective effects of carnosic acid on rat retinal ganglion cells (RGCs) among acute ocular hypertension rats.METHODS: Sixty male SPF (specific-pathogen-free) SD rats …

Rosmarinus officinalis L. and Salvia officinalis L. were found to have an antitumoral activity.

PMID:  J Complement Integr Med. 2020 Mar 31. Epub 2020 Mar 31. PMID: 32229691 Abstract Title:  The cytotoxic activity of Salvia officinalis L. and Rosmarinus officinalis L. Leaves extracts on human glioblastoma cell line and their antioxidant effect. Abstract:  Background Rosmarinus officinalis L. (Rosemary) and Salvia officinalis L. (Sage) are two Mediterranean species growing spontaneously …

Specific inhibition of S. aureus virulence using topical formulations of rosemary extract may offer a practical approach to preventing and treating flares of atopic dermatitis.

PMID:  Antibiotics (Basel). 2020 Mar 31 ;9(4). Epub 2020 Mar 31. PMID: 32244277 Abstract Title:  (Rosemary) Extracts Containing Carnosic Acid and Carnosol are Potent Quorum Sensing Inhibitors ofVirulence. Abstract:  is an opportunistic pathogen and a common cause of skin infection.also plays a role in the pathogenesis of the chronic inflammatory skin disease, atopic dermatitis.virulence involves …

α-bisabolol-loaded lipid-core nanocapsules reduce lipopolysaccharide-induced pulmonary inflammation in mice.

PMID:  Int J Nanomedicine. 2017 ;12:4479-4491. Epub 2017 Jun 19. PMID: 28684908 Abstract Title:  α-bisabolol-loaded lipid-core nanocapsules reduce lipopolysaccharide-induced pulmonary inflammation in mice. Abstract:  Acute respiratory distress syndrome (ARDS) is a severe clinical condition of respiratory failure due to an intense inflammatory response with different etiologies. Despite all efforts, therapy remains limited, and ARDS is …

Alpha-bisobolol possesses corneal antinociceptive activity.

PMID:  Pharm Biol. 2017 Dec ;55(1):1089-1092. PMID: 28193100 Abstract Title:  Corneal antinociceptive effect of (-)-α-bisabolol. Abstract:  CONTEXT: (-)-α-Bisabolol (BISA) is a sesquiterpene alcohol widely used as scent in cosmetic preparations, perfumes, shampoos, toilet soaps and other toiletries with potential for use in the pharmaceutical area.OBJECTIVE: To evaluate the corneal antinociceptive efficacy of BISA and to …

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