The vitamin D-antimicrobial peptide pathway and its role in protection against infection.

PMID:  Future Microbiol. 2009 Nov ;4(9):1151-65. PMID: 19895218 Abstract Title:  The vitamin D-antimicrobial peptide pathway and its role in protection against infection. Abstract:  Vitamin D deficiency has been correlated with increased rates of infection. Since the early 19th century, both environmental (i.e., sunlight) and dietary sources (cod liver) of vitamin D have been identified as …

Mechanisms underlying the effect of vitamin D on the immune system.

PMID:  Proc Nutr Soc. 2010 Aug ;69(3):286-9. Epub 2010 Jun 2. PMID: 20515520 Abstract Title:  Mechanisms underlying the effect of vitamin D on the immune system. Abstract:  Vitamin D and the vitamin D receptor (VDR) have been shown to be important regulators of the immune system. In particular, vitamin D and VDR deficiency exacerbates experimental …

Current status in vitamin D and regulatory T cells–immunological implications.

PMID:  Rev Med Chir Soc Med Nat Iasi. 2013 Oct-Dec;117(4):965-73. PMID: 24502077 Abstract Title:  Current status in vitamin D and regulatory T cells–immunological implications. Abstract:  There has been a continuous effort to understand possible non-Ca metabolism roles of vitamin D, including its role in the immune system and, in particular, in T cell-medicated immunity. Vitamin …

The present study suggests that Vitamin D3 is a potentially useful agent for limiting influenza A virus-induced cellular injury via its pro-autophagic action.

PMID:  Virus Res. 2020 Mar 28 ;282:197936. Epub 2020 Mar 28. PMID: 32234325 Abstract Title:  Analysis of influenza virus-induced perturbation in autophagic flux and its modulation during Vitamin D3 mediated anti-apoptotic signaling. Abstract:  Vitamin D3/Calcitriol supplementation in humans is associated with reduced incidence and severity during influenza A virus (IAV) infection. Apoptosis in response to …

Vitamin D suppresses ovarian cancer growth and invasion by targeting long non-coding RNA CCAT2.

PMID:  Int J Mol Sci. 2020 Mar 27 ;21(7). Epub 2020 Mar 27. PMID: 32230936 Abstract Title:  Vitamin D Suppresses Ovarian Cancer Growth and Invasion by Targeting Long Non-Coding RNA CCAT2. Abstract:  Ovarian cancer is the most deadly gynecologic cancer among women worldwide. Poor response to current treatment makes it necessary to discover new diagnostic …

Calcitriol ameliorates kidney injury through reducing podocytopathy, tubular injury, inflammation and fibrosis.

PMID:  Kobe J Med Sci. 2020 Mar 27 ;65(5):E153-E163. Epub 2020 Mar 27. PMID: 32249272 Abstract Title:  Calcitriol Ameliorates Kidney Injury Through Reducing Podocytopathy, Tubular Injury, Inflammation and Fibrosis in 5/6 Subtotal Nephrectomy Model in Rats. Abstract:  Chronic kidney diseases (CKDs) lead to end-stage renal diseases (ESRD) which are characterized by glomerulosclerosis, tubular injury, anemia, …

Vitamin D and respiratory infection in adults.

PMID:  Proc Nutr Soc. 2012 Feb ;71(1):90-7. Epub 2011 Nov 25. PMID: 22115013 Abstract Title:  Vitamin D and respiratory infection in adults. Abstract:  Vitamin D insufficiency is a global issue that has significant implications for health. The classical role of vitamin D in bone mineralisation is well known; vitamin D deficiency leads to rickets, osteomalacia …

Vitamin D endocrine system involvement in autoimmune rheumatic diseases.

PMID:  Autoimmun Rev. 2011 Dec ;11(2):84-7. Epub 2011 Aug 16. PMID: 21864722 Abstract Title:  Vitamin D endocrine system involvement in autoimmune rheumatic diseases. Abstract:  Vitamin D is synthesized from cholesterol in the skin (80-90%) under the sunlight and then metabolized into an active D hormone in liver, kidney and peripheral immune/inflammatory cells. These endocrine-immune effects …

Vitamin D and lung disease.

PMID:  Thorax. 2012 Nov ;67(11):1018-20. Epub 2012 Aug 30. PMID: 22935474 Abstract Title:  Vitamin D and lung disease. Abstract:  The classic role of vitamin D in the regulation of calcium and phosphate metabolism, and its effects on bone health, are well established. More recently a critical role in immunity and respiratory health has been proposed. …

The molecular and clinical evidence of vitamin D signaling as a modulator of the immune system: Role in Behçet’s disease.

PMID:  Immunol Lett. 2019 06 ;210:10-19. Epub 2019 Mar 29. PMID: 30935876 Abstract Title:  The molecular and clinical evidence of vitamin D signaling as a modulator of the immune system: Role in Behçet's disease. Abstract:  Various tissues and cell types are the targets of vitamin D. However, the major targets of vitamin D in the …

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