This delivers an outline of thymoquinone role in cancer inhibition and prevention of cancer.

PMID:  Curr Pharm Biotechnol. 2020 Apr 15. Epub 2020 Apr 15. PMID: 32297580 Abstract Title:  Thymoquinone, an Active Compound of Nigella Sativa: Role in Prevention and Treatment of Cancer. Abstract:  BACKGROUND: Cancer is the leading cause of death worldwide and current mode of cancer treatment causes side effects on normal cells and are still the …

Investigation of the protective effect of Nigella sativa oil in cisplatin induced oral mucositis.

PMID:  Turk Arch Otorhinolaryngol. 2020 Mar ;58(1):10-15. Epub 2019 Sep 2. PMID: 32313889 Abstract Title:  Investigation of the Protective Effect of Nigella Sativa Oil in Cisplatin Induced Oral Mucositis: An Experimental Study. Abstract:  Objective: The aim of this experimental study was to investigate the histopathologic effect of Nigella Sativa oil (NSO) on cisplatin (Cis) induced …

Antibiotic resistance in acne has been increasing worldwide.

PMID:  Eur J Dermatol. 2016 Apr 1 ;26(2):127-32. PMID: 26711531 Abstract Title:  Bacteriological resistance in acne: A call to action. Abstract:  Acne is common in adolescence but is also increasingly seen in adulthood, with about 40% of adults being affected. Topical and systemic oral antibiotics have been used for more than 40 years in the …

There is evidence that suggests topically-applied green tea polyphenols may reduce sebum secretion and be beneficial in the treatment of acne.

PMID:  Antioxidants (Basel). 2016 Dec 29 ;6(1). Epub 2016 Dec 29. PMID: 28036057 Abstract Title:  Green Tea and Other Tea Polyphenols: Effects on Sebum Production and Acne Vulgaris. Abstract:  Polyphenols are antioxidant molecules found in many foods including nuts, fruits, vegetables, chocolate, wine, and tea. Polyphenols have antimicrobial, anti-inflammatory, and antineoplastic properties. Recent studies suggest …

Identification of berberine as a novel drug for the treatment of multiple myeloma via targeting UHRF1.

PMID:  BMC Biol. 2020 03 25 ;18(1):33. Epub 2020 Mar 25. PMID: 32213189 Abstract Title:  Identification of berberine as a novel drug for the treatment of multiple myeloma via targeting UHRF1. Abstract:  BACKGROUND: Current therapies for multiple myeloma (MM) are associated with toxicity and resistance, highlighting the need for novel effective therapeutics. Berberine (BBR), a …

Systematic review and meta-analysis on efficacy and safety of berberine for dyslipidemia

PMID:  Zhongguo Zhong Yao Za Zhi. 2020 Feb ;45(3):664-673. PMID: 32237527 Abstract Title:  [Systematic review and Meta-analysis on efficacy and safety of berberine for dyslipidemia]. Abstract:  To evaluate the clinical efficacy and safety of berberine in the treatment of dyslipidemia. In this review, CNKI, WanFang, VIP, CBM, PubMed, Cochrane Library, EMbase, and Medline(OVID) were retrieved …

Novel regulation of miR-34a-5p and HOTAIR by the combination of berberine and gefitinib leading to inhibition of EMT in human lung cancer.

PMID:  J Cell Mol Med. 2020 Apr 5. Epub 2020 Apr 5. PMID: 32248643 Abstract Title:  Novel regulation of miR-34a-5p and HOTAIR by the combination of berberine and gefitinib  leading to inhibition of EMT in human lung cancer. Abstract:  HOTAIR is an important carcinogenic lncRNA and involves in tumorigenesis, and invasion. MiR-34a-5p functions as a …

Berberine attenuates Aβ42-induced neuronal damage through regulating circHDAC9/miR-142-5p axis in human neuronal cells.

PMID:  Life Sci. 2020 Apr 3 ;252:117637. Epub 2020 Apr 3. PMID: 32251633 Abstract Title:  Berberine attenuates Aβ42-induced neuronal damage through regulating circHDAC9/miR-142-5p axis in human neuronal cells. Abstract:  BACKGROUND: Berberine plays a neuroprotective role in neurodegenerative diseases, including Alzheimer's disease (AD). Circular RNAs (circRNAs) function as crucial players in AD pathogenesis. In the current …

Mechanisms of berberine for the treatment of atherosclerosis based on network pharmacology.

PMID:  Evid Based Complement Alternat Med. 2020 ;2020:3568756. Epub 2020 Mar 19. PMID: 32256641 Abstract Title:  Mechanisms of Berberine for the Treatment of Atherosclerosis Based on Network Pharmacology. Abstract:  Atherosclerosis is a common metabolic disease characterized by lipid metabolic disorder. The processes of atherosclerosis include endothelial dysfunction, new endothelial layer formation, lipid sediment, foam cell …

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