PMID: Curr Pharm Biotechnol. 2020 Apr 15. Epub 2020 Apr 15. PMID: 32297580 Abstract Title: Thymoquinone, an Active Compound of Nigella Sativa: Role in Prevention and Treatment of Cancer. Abstract: BACKGROUND: Cancer is the leading cause of death worldwide and current mode of cancer treatment causes side effects on normal cells and are still the …
Author Archives: Taylor Mercado
Investigation of the protective effect of Nigella sativa oil in cisplatin induced oral mucositis.
PMID: Turk Arch Otorhinolaryngol. 2020 Mar ;58(1):10-15. Epub 2019 Sep 2. PMID: 32313889 Abstract Title: Investigation of the Protective Effect of Nigella Sativa Oil in Cisplatin Induced Oral Mucositis: An Experimental Study. Abstract: Objective: The aim of this experimental study was to investigate the histopathologic effect of Nigella Sativa oil (NSO) on cisplatin (Cis) induced …
Antibiotic resistance in acne has been increasing worldwide.
PMID: Eur J Dermatol. 2016 Apr 1 ;26(2):127-32. PMID: 26711531 Abstract Title: Bacteriological resistance in acne: A call to action. Abstract: Acne is common in adolescence but is also increasingly seen in adulthood, with about 40% of adults being affected. Topical and systemic oral antibiotics have been used for more than 40 years in the …
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There is evidence that suggests topically-applied green tea polyphenols may reduce sebum secretion and be beneficial in the treatment of acne.
PMID: Antioxidants (Basel). 2016 Dec 29 ;6(1). Epub 2016 Dec 29. PMID: 28036057 Abstract Title: Green Tea and Other Tea Polyphenols: Effects on Sebum Production and Acne Vulgaris. Abstract: Polyphenols are antioxidant molecules found in many foods including nuts, fruits, vegetables, chocolate, wine, and tea. Polyphenols have antimicrobial, anti-inflammatory, and antineoplastic properties. Recent studies suggest …
Identification of berberine as a novel drug for the treatment of multiple myeloma via targeting UHRF1.
PMID: BMC Biol. 2020 03 25 ;18(1):33. Epub 2020 Mar 25. PMID: 32213189 Abstract Title: Identification of berberine as a novel drug for the treatment of multiple myeloma via targeting UHRF1. Abstract: BACKGROUND: Current therapies for multiple myeloma (MM) are associated with toxicity and resistance, highlighting the need for novel effective therapeutics. Berberine (BBR), a …
Systematic review and meta-analysis on efficacy and safety of berberine for dyslipidemia
PMID: Zhongguo Zhong Yao Za Zhi. 2020 Feb ;45(3):664-673. PMID: 32237527 Abstract Title: [Systematic review and Meta-analysis on efficacy and safety of berberine for dyslipidemia]. Abstract: To evaluate the clinical efficacy and safety of berberine in the treatment of dyslipidemia. In this review, CNKI, WanFang, VIP, CBM, PubMed, Cochrane Library, EMbase, and Medline(OVID) were retrieved …
Turmeric: A Natural Remedy for Children and Teens with Asthma
There’s mounting evidence of the multiple healing properties of turmeric against pain and common ailments such as osteoarthritis and rheumatoid arthritis
Novel regulation of miR-34a-5p and HOTAIR by the combination of berberine and gefitinib leading to inhibition of EMT in human lung cancer.
PMID: J Cell Mol Med. 2020 Apr 5. Epub 2020 Apr 5. PMID: 32248643 Abstract Title: Novel regulation of miR-34a-5p and HOTAIR by the combination of berberine and gefitinib leading to inhibition of EMT in human lung cancer. Abstract: HOTAIR is an important carcinogenic lncRNA and involves in tumorigenesis, and invasion. MiR-34a-5p functions as a …
Berberine attenuates Aβ42-induced neuronal damage through regulating circHDAC9/miR-142-5p axis in human neuronal cells.
PMID: Life Sci. 2020 Apr 3 ;252:117637. Epub 2020 Apr 3. PMID: 32251633 Abstract Title: Berberine attenuates Aβ42-induced neuronal damage through regulating circHDAC9/miR-142-5p axis in human neuronal cells. Abstract: BACKGROUND: Berberine plays a neuroprotective role in neurodegenerative diseases, including Alzheimer's disease (AD). Circular RNAs (circRNAs) function as crucial players in AD pathogenesis. In the current …
Mechanisms of berberine for the treatment of atherosclerosis based on network pharmacology.
PMID: Evid Based Complement Alternat Med. 2020 ;2020:3568756. Epub 2020 Mar 19. PMID: 32256641 Abstract Title: Mechanisms of Berberine for the Treatment of Atherosclerosis Based on Network Pharmacology. Abstract: Atherosclerosis is a common metabolic disease characterized by lipid metabolic disorder. The processes of atherosclerosis include endothelial dysfunction, new endothelial layer formation, lipid sediment, foam cell …