An increase in the percentage of sperm cells and decrease of sperm motility of abnormal morphology is associated with the duration of exposure to the waves emitted by a GSM mobile phone.

PMID: 

Ann Agric Environ Med. 2007 ;14(1):169-72. PMID: 17655195

Abstract Title: 

Evaluation of the effect of using mobile phones on male fertility.

Abstract: 

The problem of the lack of offspring is a phenomenon concerning approximately 15% of married couples in Poland. Infertility is defined as inability to conceive after a year of sexual intercourses without the use of contraceptives. In half of the cases the causative factor is the male. Males are exposed to the effect of various environmental factors, which may decrease their reproductive capabilities. A decrease in male fertility is a phenomenon which occurs within years, which may suggest that one of the reasons for the decrease in semen parameters is the effect of the development of techniques in the surrounding environment. A hazardous effect on male fertility may be manifested by a decrease in the amount of sperm cells, disorders in their mobility, as well as structure. The causative agents may be chemical substances, ionizing radiation, stress, as well as electromagnetic waves. The objective of the study was the determination of the effect of the usage of cellular phones on the fertility of males subjected to marital infertility therapy. The following groups were selected from among 304 males covered by the study: Group A: 99 patients who did not use mobile phones, Group B: 157 males who have used GSM equipment sporadically for the period of 1-2 years, and Group C: 48 people who have been regularly using mobile phone for more than 2 years. In the analysis of the effect of GSM equipment on the semen it was noted that an increase in the percentage of sperm cells of abnormal morphology is associated with the duration of exposure to the waves emitted by the GSM phone. It was also confirmed that a decrease in the percentage of sperm cells in vital progressing motility in the semen is correlated with the frequency of using mobile phones.

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This study concludes regular cellular telephone use does not appear to be associated with a higher risk of intratemporal facial nerve tumor. However, the short duration of use prevents long-term cell phone use from being excluded as a factor.

PMID: 

Laryngoscope. 2003 Apr ;113(4):663-7. PMID: 12671425

Abstract Title: 

Cellular telephone use and risk of intratemporal facial nerve tumor.

Abstract: 

OBJECTIVES/HYPOTHESIS: Microwave radiation exposure from cellular telephone use has been implicated in the development of intracranial tumors. The intratemporal facial nerve (IFN) is exposed to higher levels of cellular telephone radiation than intracranial tissues. The purpose of the study was to determine whether cellular telephone use is associated with an increased risk of IFN tumors.STUDY DESIGN: Case-control using a structured telephone survey at an academic, tertiary-care referral center.METHODS: Patients with IFN tumors (n = 18) were case-matched with patients treated for acoustic neuroma (n = 51), rhinosinusitis (n = 72), and dysphonia or gastroesophageal reflux disease (n = 69). Risk of facial nerve tumorigenesis was compared by extent of cellular telephone use and other risk factors.RESULTS: The odds ratio of developing an IFN tumor was 0.6 (95% CI, 0.2-1.9) with any handheld cellular telephone use and 0.4 (95% CI, 0.1-2.1) with regular cellular telephone use. No factors were associated with an increased risk for IFN tumor development.CONCLUSIONS: Regular cellular telephone use does not appear to be associated with a higher risk of IFN tumor development. The short duration of widespread cellular telephone use precludes definite exclusion as a risk for IFN tumor development.

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This study notes that electromagnetic exposed individuals demonstrate genotoxic effects in most studies, however, the authors criticize the validity of these studies.

PMID: 

Mutat Res. 2009 Mar-Jun;681(2-3):259-70. Epub 2008 Nov 27. PMID: 19073278

Abstract Title: 

Genetic damage in subjects exposed to radiofrequency radiation.

Abstract: 

Despite many research efforts and public debate there is still great concern about the possible adverse effects of radiofrequency (RF) radiation on human health. This is especially due to the enormous increase of wireless mobile telephones and other telecommunication devices throughout the world. The possible genetic effects of mobile phone radiation and other sources of radiofrequencies constitute one of the major points of concern. In the past several review papers were published on laboratory investigations that were devoted to in vitro and in vivo animal (cyto)genetic studies. However, it may be assumed that some of the most important observations are those obtained from studies with individuals that were exposed to relatively high levels of radiofrequency radiation, either as a result of their occupational activity or as frequent users of radiofrequency emitting tools. In this paper the cytogenetic biomonitoring studies of RF-exposed humans are reviewed. A majority of these studies do show that RF-exposed individuals have increased frequencies of genetic damage (e.g., chromosomal aberrations) in their lymphocytes or exfoliated buccal cells. However, most of the studies, if not all, have a number of shortcomings that actually prevents any firm conclusion. Radiation dosimetry was lacking in all papers, but some of the investigations were flawed by much more severe imperfections. Large well-coordinated multidisciplinary investigations are needed in order to reach any robust conclusion.

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Chronic mobile phone usage revealed high frequency hearing loss in the dominant ear compared to the non dominant ear.

PMID: 

Indian J Otolaryngol Head Neck Surg. 2014 Jan ;66(Suppl 1):169-72. Epub 2011 Dec 15. PMID: 24533378

Abstract Title: 

High-frequency hearing loss among mobile phone users.

Abstract: 

The objective of this study is to assess high frequency hearing (above 8 kHz) loss among prolonged mobile phone users is a tertiary Referral Center. Prospective single blinded study. This is the first study that used high-frequency audiometry. The wide usage of mobile phone is so profound that we were unable to find enough non-users as a control group. Therefore we compared the non-dominant ear to the dominant ear using audiometric measurements. The study was a blinded study wherein the audiologist did not know which was the dominant ear. A total of 100 subjects were studied. Of the subjects studied 53% were males and 47% females. Mean age was 27. The left ear was dominant in 63%, 22% were dominant in the right ear and 15% did not have a preference. This study showed that there is significant loss in the dominant ear compared to the non-dominant ear (P 

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High-level radiofrequency electromagnetic radiation exposure increased stress hormone secretion.

PMID: 

Rev Environ Health. 2005 Apr-Jun;20(2):151-61. PMID: 16121836

Abstract Title: 

Variations of melatonin and stress hormones under extended shifts and radiofrequency electromagnetic radiation.

Abstract: 

We studied the time-of-day variations in urinary levels of 6-sulphatoxy-melatonin and three stress hormones in operators working fast-rotating extended shifts under radiofrequency electromagnetic radiation (EMR). The excretion rate of the hormones was monitored by radioimmunoassay and spectrofluorimetry at 4-hour intervals in a group of 36 male operators comprising 12 broadcasting station operators, 12 TV station operators, and a control group of 12 satellite station operators. Measuring the time-weighted average (TWA) of EMR exposure revealed a high-level of exposure in broadcasting station operators (TWAmean= 3.10 microW/ cm2, TWAmax = 137.00 microW/cm2), a low-level in TV station operators (TWAmean = 1.89 microW/cm2, TWAmax = 5.24 microW/cm2), and a very low level in satellite station operators. The differences among the groups remained the same after confounding factors were taken into account. Radiofrequency EMR had no effect on the typical diurnal pattern of 6-sulphatoxymelatonin. High-level radiofrequency EMR exposure significantly increased the excretion rates of cortisol (p

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Hepatic DNA damage induced by electronic cigarette exposure is associated with the modulation of NAD+/PARP1/SIRT1 axis.

PMID: 

Front Endocrinol (Lausanne). 2019 ;10:320. Epub 2019 Jun 4. PMID: 31214115

Abstract Title: 

Hepatic DNA Damage Induced by Electronic Cigarette Exposure Is Associated With the Modulation of NAD+/PARP1/SIRT1 Axis.

Abstract: 

The prevalence of electronic cigarette (e-cigarettes) use has rapidly increased worldwide. Use of tobacco products has been associated with DNA damage and metabolic syndrome. Using Apolipoprotein E knockout (ApoE) mice on a western diet (WD), a mouse model of non-alcoholic fatty liver disease (NAFLD), we recently demonstrated that nicotine in e-cigarettes activates hepatocyte apoptosis, and causes hepatic steatosis. This study examines the harmful effects of e-cigarettes on the liver with a special emphasis on DNA damage and mitochondrial dysfunction. ApoEmice were exposed to saline, e-cigarettes without nicotine or e-cigarettes with 2.4% nicotine for 12 weeks using our newly developed mouse e-cigarette exposure model system that delivers nicotine to mice leading to equivalent serum cotinine levels found in human cigarette users. Mice exposed to e-cigarette (2.4% nicotine) had increased apurinic/apyrimidinic (AP) sites, a manifestation of DNA damage. Additionally, e-cigarette (2.4% nicotine) produced a decrease in NAD+/NADH ratio and increased oxidative stress in hepatic cells, in comparison with saline and e-cigarette (0%). Western blot analysis showed that mice treated with e-cigarette (2.4% nicotine) had increased poly (ADP ribose) polymerase (PARP1) activity associated with reduced levels of Sirtuin 1 (SIRT1). Furthermore, mitochondrial DNA mutations and PTEN-induced kinase 1 (PINK1) were increased in mice treated with e-cigarette (2.4% nicotine). Transmission electron microscopy revealed that hepatocytes of mice treated with e-cigarette (2.4% nicotine) exhibited increased vacuolization of the mitochondria and a reduction in cellular organelles. These results demonstrate the adverse effects of e-cigarettes exposure leading to NAD+ deficiency which may suggest a mechanistic link between e-cigarette-induced hepatic DNA damage and mitochondrial dysfunction.

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The long term effect of the exposure to low-level radiofrequency electromagnetic radiation evoked a pronounced stress reaction in space station operators.

PMID: 

Cent Eur J Public Health. 2002 Jun ;10(1-2):24-8. PMID: 12096679

Abstract Title: 

The effect of low level radiofrequency electromagnetic radiation on the excretion rates of stress hormones in operators during 24-hour shifts.

Abstract: 

The aim of the study was to investigate the effect of long term exposure to low level radiofrequency (RF) electromagnetic (EM) radiation on the excretion rates of stress hormones in satellite station operators during 24-hour shifts. Twelve male operators at a satellite station for TV communications and space research were studied during 24-hour shifts. Dosimetric evaluation of the exposure was carried out and showed low level exposure with specific absorption of 0.1127 J.kg-1. A control group of 12 unexposed male operators with similar job task and the same shift system were studied, too. The 11-oxycorticosteroids (11-OCS), adrenaline and noradrenaline were followed by spectrofluorimetric methods on 3-hour intervals during the 24-hour shifts. The data were analyzed by tests for interindividual analysis, Cosinor analysis and analysis of variance (ANOVA). Significant increase in the 24-hour excretion of 11-OCS and disorders in its circadian rhythm, manifested by increase in the mesor, decrease in the amplitude and shift in the acrophase were found in the exposed operators. The changes in the excretion rates of the catecholamines were significant and showed greater variability of both variables. The long term effect of the exposure to low-level RF EM radiation evoked pronounced stress reaction with changes in the circadian rhythm of 11-OCS and increased variability of catecholamines secretion. The possible health hazards associated with observed alteration in the stress system need to be clarified by identification of their significance and prognostic relevance.

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These data show that the radiofrequency electromagnetic radiation contributes to adverse effects on the cardiovascular system.

PMID: 

Int J Hyg Environ Health. 2006 Mar ;209(2):133-8. Epub 2005 Nov 10. PMID: 16503299

Abstract Title: 

Cardiovascular risk in operators under radiofrequency electromagnetic radiation.

Abstract: 

The aim of the study was to assess the long-term effects of radiofrequency electromagnetic radiation (EMR) on the cardiovascular system. Two groups of exposed operators (49 broadcasting (BC) station and 61 TV station operators) and a control group of 110 radiorelay station operators, matched by sex and age, with similar job characteristics except for the radiofrequency EMR were studied. The EMR exposure was assessed and the time-weighted average (TWA) was calculated. The cardiovascular risk factors arterial pressure, lipid profile, body mass index, waist/hip ratio, smoking, and family history of cardiovascular disease were followed. The systolic and diastolic blood pressure (SBP and DBP), total cholesterol (TC) and low-density lipoprotein cholesterol (LDL-C) were significantly higher in the two exposed groups. It was found that the radiofrequency EMR exposure was associated with greater chance of becoming hypertensive and dyslipidemic. The stepwise multiple regression equations showed that the SBP and TWA predicted the high TC and high LDL-C, while the TC, age and abdominal obesity were predictors for high SBP and DBP. In conclusion, our data show that the radiofrequency EMR contributes to adverse effects on the cardiovascular system.

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Electronic and conventional cigarette use were each significantly associated with increased periodontal disease rates.

PMID: 

J Periodontol. 2019 Jul 29. Epub 2019 Jul 29. PMID: 31355936

Abstract Title: 

Associations of Electronic and Conventional Cigarette Use with Periodontal Disease in South Korean Adults.

Abstract: 

BACKGROUND: The aim of this study was to examine the association of conventional cigarette smoking and electronic cigarette vaping with periodontal disease in South Korean adults.METHODS: For this study, data from 13,551 participants, a subset derived from the Korean National Health and Nutrition Examination Survey conducted between 2013 and 2015, were examined. Participants were divided into four categories: electronic cigarettes vapers, conventional cigarettes smokers, ex-users, and non-users. Periodontal status was measured by the Community Periodontal Index. Multiple logistic regression analysis was performed to examine the association of periodontal disease with smoking and vaping individually.RESULTS: Out of 187 men and 35 women who vape electronic cigarette, 67 (35.8%) men and 10 (28.6%) women had periodontal diseases. Out of 1,957 men and 363 women who smoke conventional cigarettes, 861 (44.0%) men and 121 (35.3%) women had periodontal diseases. Periodontal disease was more prevalent in each vapers and smokers than non-users in men (electronic cigarettes: OR = 2.34, 95% CI = 1.52-3.59, conventional cigarettes: OR = 2.17, 95% CI = 1.76-2.68). Furthermore, both vaping and smoking had significant relation to dental caries, toothache, and dental damages.CONCLUSIONS: Electronic and conventional cigarette use were each significantly associated with increased periodontal disease rates. After adjusting for demographic, socioeconomic, and health-related characteristics, both vaping and smoking each had significant association with periodontal diseases. Therefore, this study suggests that vaping may not be a safe alternative to smoking. Cessation of both types of cigarettes is necessary for maintaining oral health. This article is protected by copyright. All rights reserved.

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This paper reviews the latest developments in the field of spin chemistry which may explain the effects of electromagnetic fields on the body.

PMID: 

Philos Trans A Math Phys Eng Sci. 2004 Dec 15 ;362(1825):2573-89. PMID: 15539359

Abstract Title: 

A study of spin chemistry in weak magnetic fields.

Abstract: 

This paper reviews the latest developments in the field of spin chemistry with a particular focus on the effects of weak static and/or oscillating magnetic fields (typically smaller than the average hyperfine coupling) on radical recombination reactions. Anisotropic magnetic field effects and their significance in the debate about potential mechanisms controlling magnetoreception in birds are discussed.

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