Super-low intensity radiofrequency radiation at microwatt reasonant frequencies resulted in changes in genes and problems with chromatin conformation.

PMID: 

Biochim Biophys Acta. 1997 Oct 20 ;1336(3):465-73. PMID: 9367174

Abstract Title: 

Effects of zero magnetic field on the conformation of chromatin in human cells.

Abstract: 

The effects of zero magnetic field on human VH-10 fibroblasts and lymphocytes were studied by the method of anomalous viscosity time dependencies (AVTD). A decrease of about 20% in the AVTD peaks was observed within 40 to 80 min of exposure of fibroblasts. This decrease was transient and disappeared 120 min after beginning of exposure. Similar kinetics for the effect of zero field was observed when cells were exposed 20 min and then kept at an ambient field. A 20% decrease of the AVTD peaks (p

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Long-term exposure to low-density ELF-EMF may cause a decrease in adaptive immune response, especially in Th1 subset.

PMID: 

Electromagn Biol Med. 2019 ;38(1):84-95. Epub 2018 Dec 6. PMID: 30518268

Abstract Title: 

A review on the effects of extremely low frequency electromagnetic field (ELF-EMF) on cytokines of innate and adaptive immunity.

Abstract: 

Extremely low frequency electromagnetic field (ELF-EMF) is produced extensively in modern technologies. Numerous in vitro and in vivo studies have shown that ELF-EMF has both stimulatory and inhibitory effects on the immune system response. This review was conducted on effects of ELF-EMF on cytokines of innate and adaptive immunity. Mechanisms of ELF-EMF, which may modulate immune cell responses, were also studied. Physical and biological parameters of ELF-EMF can interact with each other to create beneficial or harmful effect on the immune cell responses by interfering with the inflammatory or anti-inflammatory cytokines. According to the studies, it is supposed that short-term (2-24 h/d up to a week) exposure of ELF-EMF with strong density may increase innate immune response due to an increase of innate immunity cytokines. Furthermore, long-term (2-24 h/d up to 8 years) exposure to low-density ELF-EMF may cause a decrease in adaptive immune response, especially in T1 subset.

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Long term power frequency electromagnetic fields exposure influences the causal network connection pattern of local field potentials during working memory.

PMID: 

Sheng Wu Yi Xue Gong Cheng Xue Za Zhi. 2018 12 25 ;35(6):829-836. PMID: 30583305

Abstract Title: 

[Long term power frequency electromagnetic fields exposure influences the causal network connection pattern of local field potentials during working memory].

Abstract: 

The possible influence of electromagnetic field (EMF) on the function of neural systems has been widely concerned. In this article, we intend to investigate the effects of long term power frequency EMF exposure on brain cognitive functions and it's mechanism. The Sprague-Dawley (SD) rats were randomly divided into 3 groups: the rats in EMFⅠ group were placed in the 2 mT power frequency EMF for 24 days. The rats in EMF Ⅱ group were placed in the 2 mT power frequency EMF for 48 days. The rats in control group were not exposed to the EMF. Then, the 16 channel local field potentials (LFPs) were recorded from rats' prefrontal cortex (PFC) in each group during the working memory (WM) tasks. The causal networks of LFPs were also established by applying the directed transfer function (DTF). Based on that, the differences of behavior and the LFPs network connection patterns between different groups were compared in order to investigate the influence of long term power frequency EMF exposure on working memory. The results showed the rats in the EMF Ⅱ group needed more training to reach the task correction criterion (over 80%). Moreover, the causal network connection strength and the global efficiency of the rats in EMF Ⅰ and EMF Ⅱ groups were significantly lower than the corresponding values of the control group. Meanwhile, significant differences of causal density values were found between EMF Ⅱ group and the other two groups. These results indicate that long term exposure to 2 mT power frequency EMF will reducethe connection strength and the information transfer efficiency of the LFPs causal network in the PFC, as well as the behavior performance of the rats. These results may explain the effect of EMF exposure on working memory from the view of neural network connectivity and provide a support for further studies on the mechanism of the effect of EMF on cognition.

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Early exposure to radiofrequency electromagnetic fields at 1850 MHz affects auditory circuits in early postnatal mice.

PMID: 

Sci Rep. 2019 Jan 23 ;9(1):377. Epub 2019 Jan 23. PMID: 30674958

Abstract Title: 

Early exposure to radiofrequency electromagnetic fields at 1850 MHz affects auditory circuits in early postnatal mice.

Abstract: 

In the present study, we measured the spontaneous post synaptic currents (sPSCs) at the post synaptic principle cells of the medial nucleus of the trapezoid body (MNTB) in early postnatal mice after exposure to 1850 MHz radiofrequency electromagnetic fields (RF-EMF). sPSC frequencies and amplitudes were significantly increased in the RF-EMF exposed group. Moreover, the number of synaptic vesicles in the calyx of Held was significantly increased in presynaptic nerve terminals. Following RF-EMF exposure, the number of docking synaptic vesicles in the active zone increased, thereby expanding the total length of the presynaptic active zone in the calyx of Held. These data suggest that the increased sPSCs are a result of greater synaptic vesicle release from presynaptic nerves. However, we found no morphological changes in the inner hair cell ribbon synapses. Further, there were no significant changes in the hearing threshold of the auditory brainstem response at postnatal day 15. Our results indicate that exposure to RF-EMF at an early postnatal stage might directly affect brainstem auditory circuits, but it does not seem to alter general sound perception.

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Exposure to electromagnetic fields from GSM 900 and 1800 generated by base stations contributed to the occurrence of depressive disorders.

PMID: 

Neuro Endocrinol Lett. 2019 Mar ;39(8):550-560. PMID: 30927760

Abstract Title: 

The influence of electromagnetic fields generated by wireless connectivity systems on the occurrence of emotional disorders in women: A preliminary report.

Abstract: 

OBJECTIVES: The aim of the study was to assess the influence of electromagnetic fields (EMFs) generated by wireless connectivity systems on the occurrence of emotional disorders in women working in the health service and in trade. We also analyzed the relationship between physical activity and emotional state.METHODS AND RESULTS: The study was conducted on a sample of 200 women aged 25 to 35, in Lublin, Poland, in 2017. Shopping center staff spent more time using their mobile phones for conversations and online activities. Medical staff were exposed to stronger electromagnetic fields generated by stationary wireless phones than shopping center staff, they were less exposed to the effect of relay stations.CONCLUSIONS: The study showed that exposure to electromagnetic fields from GSM 900 and 1800 generated by base stations contributed to the occurrence of depressive disorders among medical personnel, while exposure to WLAN EMF had the opposite effect. Spending time on phone conversations decreased the feeling of depression and increased trait anxiety in medical staff. Spending free time on physical activity intensified depressive states in women working in trade. Further studies on the influence of low-frequency EMFs on the human nervous system are needed.

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Exposure towards 2.45 GHz RF-EMR emitted by Wi-Fi transmitter is hazardous on the male reproductive system.

PMID: 

Tohoku J Exp Med. 2019 07 ;248(3):169-179. PMID: 31353326

Abstract Title: 

Adverse Effects of Wi-Fi Radiation on Male Reproductive System: A Systematic Review.

Abstract: 

Extensive use of Wi-Fi has contributed to radiofrequency electromagnetic radiation (RF-EMR) pollution in environment. Various studies have been conducted to evaluate the effect of RF-EMR emitted by Wi-Fi transmitter on male reproduction health. However, there are conflicting findings between studies. Thus, this review aims to elucidate the possible effects of 2.45 GHz Wi-Fi exposure on both animal and human male reproductive system. A computerized database search performed through MEDLINE via Ovid and PUBMED with the following set of keywords: 'Wi-Fi or WiFi or wireless fidelity or Wi-Fi router or WiFi router or electromagnetic or radiofrequency radiation' AND 'sperm or spermatozoa or spermatogenesis or semen or seminal plasma or testes or testis or testosterone or male reproduction' had returned 526 articles. Only 17 studies conformed to pre-set inclusion criterion. Additional records identified through Google Scholar and reviewed article further revealed six eligible articles. A total of 23 articles were used for data extraction, including 15 studies on rats, three studies on mice, and five studies on human health. Sperm count, motility and DNA integrity were the most affected parameters when exposed to RF-EMR emitted by Wi-Fi transmitter. Unfortunately, sperm viability and morphology were inconclusive. Structural and/or physiological analyses of the testes showed degenerative changes, reduced testosterone level, increased apoptotic cells, and DNA damage. These effects were mainly due to the elevation of testicular temperature and oxidative stress activity. In conclusion, exposure towards 2.45 GHz RF-EMR emitted by Wi-Fi transmitter is hazardous on the male reproductive system.

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Exposure to ELF-MF at levels less than the ACGIH exposure limit can produce DNA strand breaks.

PMID: 

Toxicol Ind Health. 2019 Jun ;35(6):424-430. Epub 2019 May 28. PMID: 31138035

Abstract Title: 

DNA effects of low level occupational exposure to extremely low frequency electromagnetic fields (50/60 Hz).

Abstract: 

AIMS: Exposure to extremely low frequency magnetic fields (ELF-MF) occurs from natural and artificial sources. Although ELF-MF has been classified as a suspected humans carcinogen agent by the International Agency for Research on Cancer, little is known of the effects of ELF-MF at lower exposure levels of the recommended range. In the present study, DNA damage in the peripheral blood cells of power line workers was investigated.MATERIALS AND METHODS: Occupational exposure to ELF-MF in a power plant was measured using the National Institute for Occupational Safety and Health (NIOSH) manual. Single-strand breaks (SSBs) in DNA were evaluated in 29 male utility workers as the exposed population and 28 male support personnel as the control subjects using the comet assay. Effects of ELF-MF on subjects were evaluated using DNA percent in tails, tail length, olive length, and tail moment.RESULTS: Occupational exposure levels to ELF-MF in the utility workers were less than the threshold limit values (TLV) recommended by the American Conference of Government Industrial Hygienist (ACGIH). The median value of the magnetic field at the working sites was 0.85µT. Induction of DNA damage was observed for the exposed workers compared with the controls. Olive length, tail moment, and tail DNA percent increased significantly (

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These results suggest a possible association between residential UHF-EMF exposure and amyotrophic lateral sclerosis.

PMID: 

Environ Res. 2019 Jun 11 ;176:108525. Epub 2019 Jun 11. PMID: 31226626

Abstract Title: 

Residential exposure to ultra high frequency electromagnetic fields emitted by Global System for Mobile (GSM) antennas and amyotrophic lateral sclerosis incidence: A geo-epidemiological population-based study.

Abstract: 

Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease of unknown etiology. Mobile communication antennas have increased over the last few decades. Consequently, there has been a steady increase in environmental exposure to ultra high frequency electromagnetic fields (UHF-EMFs) emitted by Global System for Mobile (GSM) communication antennas, which raises concerns about possible health risks in the general population. We aimed to evaluate the relationship between residential exposure to UHF-EMFs generated by GSM antennas and the risk of ALS in general population. A geo-epidemiological population-based study was performed in Limousin (France). ALS incident cases were identified through a register (FRALim, 2000-2012 period). A model to estimate UHF-EMF exposure was developed based on the distance and the power of GSM antennas. Exposure to multiple emissions from multiple directions was considered. A non-cumulative and a cumulative model were established. A geographic information system integrated the raster model of exposure, and the residential distribution of observed and expected cases. A generalized linear model was performed to test the association. Overall, 312 ALS cases were included. We estimated exposures below 1.72 V/m in urban areas and below 1.23 V/m in rural areas for 90% of the population. A gradient effect between UHF-EMF exposure and ALS incidence was apparent with a statistically significant trend. A significant increased risk of ALS was observed between the non-exposure category and the highest exposure category, with a relative risk of 1.78 (95% CI: 1.28-2.48) in the non-cumulative model and 1.83 (95% CI: 1.32-2.54) in the cumulative model. Our results suggest a possible association between residential UHF-EMF exposure and ALS. Ecological studies are a means of generating hypotheses. Further studies are needed to clarify the potential role of EMFs on neurodegeneration.

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The reaction of the circulatory system to stress and electromagnetic fields emitted by mobile phones.

PMID: 

Med Pr. 2019 Jul 16 ;70(4):411-424. Epub 2019 Jun 27. PMID: 31249426

Abstract Title: 

[The reaction of the circulatory system to stress and electromagnetic fields emitted by mobile phones – 24-h monitoring of ECG and blood pressure].

Abstract: 

BACKGROUND: Experimental studies have shown cardiovascular effects of electromagnetic fields (EMF) emitted by mobile phones (e.g., prolonged QTc interval and abnormal blood pressure [BP] values). Also, stress may have an impact on the cardiovascular function. However, there are practically no data regarding the joint effect of exposure to stress and EMF, with both factors pertaining, e.g., to employees of mobile network operators.MATERIAL AND METHODS: Out of 208 subjects who had taken part in survey research, 55 workers agreed to undergo resting ECG, 24-h ECG and ambulatory blood pressure monitoring (ABPM). Their health condition, occupational and life-stress levels and EMF exposure were also assessed.RESULTS: Among the workers using mobile phones for more than 60 min daily, the systolic BP values in office measurement and at night-time in ABPM were significantly higher than among the workers spending less time talking on mobile phones (p = 0.04 and p = 0.036, respectively). The workers with the highest level of occupational stress showed significantly higher systolic 24-h BP (p = 0.007) and at day-time (p = 0.002), both during work (p = 0.010) and after work (p = 0.005), and higher diastolic BP values at day-time (p = 0.028). Cardiovascular response was strongly gender-related: males showed more BP abnormalities while females displayed more impairments in ECG records. The heart rate from 24 h was significantly correlated with the level of occupational stress, after adjusting for gender, life-stress and EMF.CONCLUSIONS: The findings obtained thus far have indicated the need to conduct in-depth studies on the impact of stress and EMF emitted by mobile phones on the health effects, in order to clarify the observed gender-related differences in cardiovascular response to the combined exposure to stress and EMF. Med Pr. 2019;70(4):411-24.

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Effects of exposure to extremely low frequency electromagnetic fields on hippocampal long-term potentiation in hippocampal CA1 region.

PMID: 

Biochem Biophys Res Commun. 2019 Jul 31. Epub 2019 Jul 31. PMID: 31376941

Abstract Title: 

Effects of exposure to extremely low frequency electromagnetic fields on hippocampal long-term potentiation in hippocampal CA1 region.

Abstract: 

Exposure to environmental electromagnetic fields, especially to the extremely low-frequency (ELF 

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