The consumption of sugar-sweetened beverages has a dose-dependent effect on the risk of NAFLD.

PMID: 

Int J Environ Res Public Health. 2019 Jun 21 ;16(12). Epub 2019 Jun 21. PMID: 31234281

Abstract Title: 

Consumption of Sugar-Sweetened Beverages Has a Dose-Dependent Effect on the Risk of Non-Alcoholic Fatty Liver Disease: An Updated Systematic Review and Dose-Response Meta-Analysis.

Abstract: 

Non-alcoholic fatty liver disease (NAFLD) is a serious health problem, but the dose-response relationship between sugar-sweetened beverages (SSBs) and NAFLD remains uncertain.A systematic review and dose-response meta-analysis were conducted following the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) guidelines. Review Manager 5.3 and Stata 14.0 were used to combine trials and analyze data. The dose-response meta-analysis was performed by non-linear trend regression.Twelve studies recruiting a total of 35,705 participants were included. The results showed that the consumption of SSBs was associated with 1.39-fold increased odds of NAFLD (95% CI: 1.29-1.50,

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The consumption of sugary drinks was positively associated with the risk of overall cancer and breast cancer.

PMID: 

BMJ. 2019 07 10 ;366:l2408. Epub 2019 Jul 10. PMID: 31292122

Abstract Title: 

Sugary drink consumption and risk of cancer: results from NutriNet-Santé prospective cohort.

Abstract: 

OBJECTIVE: To assess the associations between the consumption of sugary drinks (such as sugar sweetened beverages and 100% fruit juices), artificially sweetened beverages, and the risk of cancer.DESIGN: Population based prospective cohort study.SETTING AND PARTICIPANTS: Overall, 101 257 participants aged 18 and over (mean age 42.2, SD 14.4; median follow-up time 5.1 years) from the French NutriNet-Santé cohort (2009-2017) were included. Consumptions of sugary drinks and artificially sweetened beverages were assessed by using repeated 24 hour dietary records, which were designed to register participants' usual consumption for 3300 different food and beverage items.MAIN OUTCOME MEASURES: Prospective associations between beverage consumption and the risk of overall, breast, prostate, and colorectal cancer were assessed by multi-adjusted Fine and Gray hazard models, accounting for competing risks. Subdistribution hazard ratios were computed.RESULTS: The consumption of sugary drinks was significantly associated with the risk of overall cancer (n=2193 cases, subdistribution hazard ratio for a 100mL/d increase 1.18, 95% confidence interval 1.10 to 1.27, P

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Aloe vera fermentation significantly accelerates burn injury healing.

PMID: 

Mediators Inflamm. 2019 ;2019:2020858. Epub 2019 Jan 27. PMID: 30837795

Abstract Title: 

Evaluation of the Treatment Effect ofFermentation in Burn Injury Healing Using a Rat Model.

Abstract: 

Burn injury is a growing medical problem associated with public health, and few effective agents are available for treatment of this disease. In the present study, a burn injury rat model was developed and the accelerated effect offermentation on burn injury healing was evaluated. Our results indicated thatfermentation could markedly reduce the DPPH (56.12%), O(93.5%),OH (76.12%), Fechelation (82%), and oxygen-reduction activity (0.28 g/ml) and significantly inhibited the growth of pathogensATCC 13311 (inhibition zone diameter: 14 mm),ATCC13076 (IZD: 13 mm),ATCC 12022 (IZD: 18 mm),44102 (IZD: 10 mm),ATCC 19111 (IZD: 18 mm),301 (IZD: 20 mm),COWAN1 (IZD: 19 mm), andATCC 11827 (IZD: 25 mm). Theresults indicated thatfermentation produced more eosinophils and fibroblasts and less vessel proliferation compared with the model group on the 14day, which had greatly accelerated burn injury healing via shedding of the scab and promoting hair growth. ELISA results indicated thatfermentation had significantly reduced the production of proinflammatory factors TNF-and IL-1(

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The carcinogenic potential of non-ionizing radiations: The cases of S-50 Hz MF and 1.8 GHz GSM radiofrequency radiation.

PMID: 

Basic Clin Pharmacol Toxicol. 2019 Feb 24. Epub 2019 Feb 24. PMID: 30801980

Abstract Title: 

The carcinogenic potential of non-ionizing radiations: The cases of S-50 Hz MF and 1.8 GHz GSM radiofrequency radiation.

Abstract: 

Epidemiological studies have suggested that human exposure to extremely low-frequency electromagnetic fields from the electric power and to mobile phone radiofrequency electromagnetic fields induce an increased risk of developing malignant tumours. However, no adequate laboratory data, in particular long-term carcinogenicity bioassays to support the epidemiological evidence, have yet been available. This motivated the Ramazzini Institute to embark on a first project of four large life-span carcinogenic bioassays conducted on over 7000 Sprague Dawley rats exposed from prenatal life until natural death to S-50 Hz MF alone or combined with gamma radiation or formaldehyde or aflatoxin B1. Results now available from these studies, which started concurrently, have shown that exposure to Sinusoidal-50 Hz Magnetic Field (S-50 Hz MF) combined with acute exposure to gamma radiation or to chronic administration of formaldehyde in drinking water induces a significantly increased incidence of malignant tumours in males and females. A second project of two large life-span carcinogenic bioassays was conducted on over 3000 Sprague Dawley rats exposed from prenatal life until natural death to 1.8 GHz GSM of mobile phone radio base station, alone or combined with acute exposure to gamma radiation. Early results from the experiment on 1.8 GHz GSM alone show a statistically significant increase in the incidence of heart malignant schwannoma among males exposed at the highest dose.

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Mobile phone electromagnetic radiation affects amyloid precursor protein and α-synuclein metabolism in SH-SY5Y cells.

PMID: 

Pathophysiology. 2019 Mar 1. Epub 2019 Mar 1. PMID: 30850244

Abstract Title: 

Mobile phone electromagnetic radiation affects Amyloid Precursor Protein andα-synuclein metabolism in SH-SY5Y cells.

Abstract: 

In this study, the effects of low-level, GSM emitted ElectroMagnetic Field (EMF) on Amyloid Precursor Protein (APP) and alpha-synuclein (α-syn) in human neuroblastoma cells was investigated. Our data indicated alterations on APP processing and cellular topology, following EMF exposure (ℇ = 10.51 V/m, SAR = 0.23 W/kg, exposure time: 3 times, for 10 min, for 2 days). Furthermore, changes in monomeric α-syn accumulation and multimerization, as well as induction of oxidative stress and cell death, were documented. The results presented here require further investigation to determine potential links of EMF with the molecular pathogenic mechanisms in Alzheimer's and Parkinson's Diseases.

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Higher-than-ever levels of maternal exposure to electromagnetic fields could be linked to offspring speech problems.

PMID: 

J Biomed Phys Eng. 2019 Feb ;9(1):61-68. Epub 2019 Feb 1. PMID: 30881935

Abstract Title: 

Mother's Exposure to Electromagnetic Fields before and during Pregnancy is Associated with Risk of Speech Problems in Offspring.

Abstract: 

Background: Rapid advances in technology, especially in the field of telecommunication, have led to extraordinary levels of mothers' exposures to radiofrequency electromagnetic fields (RF-EMFs) prior to or during pregnancy.Objective: The main goal of this study was to answer this question whether exposure of women to common sources of RF-EMFs either prior to or during pregnancy is related to speech problems in the offspring.Materials and Methods: In this study, mothers of 110 three-to-seven-year-old children with speech problems and 75 healthy children (control group) were interviewed. These mothers were asked whether they had exposure to different sources of EMFs such as mobile phones, mobile base stations, Wi-Fi, cordless phones, laptops and power lines. Chi square test was used to analyze the differences observed between the control and exposed groups.Results: Statistically significant associations were found between the use of cordless phone and offspring speech problems for both before pregnancy and during pregnancy maternal exposures (P=0.005 and P=0.014, respectively). However, due to high rate of mobile phone use in both groups, this study failed to show any link between mobile phone use and speech problems in offspring. Furthermore, significant associations were observed between living in the vicinity of power lines and speech problems again for both before pregnancy and during pregnancy maternal exposures (P=0.003 and P=0.002, respectively). However, exposure to other sources of non-ionizing radiation was not linked to speech problems. Moreover, exposure to ionizing radiation (e.g. radiography before and during pregnancy) was not associated with the occurrence of speech problems.Conclusion: Although this study has some limitations, it leads us to this conclusion that higher-than-ever levels of maternal exposure to electromagnetic fields could be linked to offspring speech problems.

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Effect of radiofrequency radiation on reproductive health.

PMID: 

Indian J Med Res. 2018 12 ;148(Suppl):S92-S99. PMID: 30964085

Abstract Title: 

Effect of radiofrequency radiation on reproductive health.

Abstract: 

The development of cellular phone system has greatly increased the extent and magnitude of radiofrequency radiation (RFR) exposure. The RFR emitted from mobile phone and mobile phone base stations exerts thermal and non-thermal effects. The short-term and long-term exposure to RFR may have adverse effect on humans as well as animals. Most laboratory studies have indicated a direct link between exposure to RFR and adverse biological effects. Several in vitro studies have reported that RFR induces various types of cancer and DNA or chromosomal damage. On the other hand, some animal studies have not reported adverse effects of this radiation. The present review summarizes information available on the possible effects of RFR on the reproductive health.

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A review of the possible global hazard of cell phone radiation on thyroid cells and hormones.

PMID: 

Environ Sci Pollut Res Int. 2019 Jun ;26(18):18017-18031. Epub 2019 May 6. PMID: 31062236

Abstract Title: 

The possible global hazard of cell phone radiation on thyroid cells and hormones: a systematic review of evidences.

Abstract: 

The aim of this review was to investigate the effects of possible harmful waves from either cell phone use or being within the range of the cell phone from 450 to 3800 MHz on the thyroid cells and hormones. Eight electronic datasets were systematically searched using MeSH terms, including"cell phone,""mobile phone,""GSM,""radio frequency,""smartphone,""triiodothyronine,""thyroxin,""thyroid-stimulating hormone,""T3,""T4,""TSH,"and"morphological"and all possible combinations, to identify relevant studies published up to Dec 2018. We also manually searched the reference lists of potentially selected studies to identify further relevant publications. About 161 relevant studies were initially found. After screening titles and abstracts, 139 studies were excluded, and finally 22 studies (comprising 7182 cases) were included in the qualitative synthesis. Of the 22 included studies, 11 studies reported changes in T3 and T4 levels (six reported a decrease in T3 levels and one reported increase in it); moreover, five found decreased T4 levels and two studies an increased level. In other 10 studies, TSH alteration was reported. Of these, two studies reported a decrease in TSH level and one reported an increase in the hormone levels, while in the remaining studies non-significant changes were reported. Finally, seven studies examined histological changes in the thyroid gland follicles and showed that the volume of these cells was reduced. Based on the evidence discussed above, the reduction in diameter of thyroid follicles is potentially linked with cell phone radiation. Exposure may negatively influence the iodine uptake in the thyroid gland or increases temperature effect on the thyroid gland. However, further research are needed in order to show that the level of TSH and thyroid hormone suppression by microwave.

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The use of dental light cure devices and mobile phones can accelerate the microleakage of amalgam restorations.

PMID: 

J Biomed Phys Eng. 2019 Apr ;9(2):227-232. Epub 2019 Apr 1. PMID: 31214528

Abstract Title: 

Synergistic Effect of Radiofrequency Electromagnetic Fields of Dental Light Cure Devices and Mobile Phones Accelerates the Microleakage of Amalgam Restorations: An in vitro Study.

Abstract: 

Background: Previous studies have shown that exposure to electromagnetic fields produced by magnetic resonance imaging or mobile phones can lead to increased microleakage of dental amalgam.Objective: The aim of the present study was to investigate the effect of electromagnetic field of a commercial dental light cure device and a common GSM mobile phone on microleakage of amalgam restorations.Materials and Methods: Identical class V cavities were prepared on the buccal surfaces of 60 non-carious extracted human teeth. The samples were randomly divided into 4 groups of 20 samples each. The samples in the first group were not exposed to electromagnetic fields, while the second and the third groups were exposed to electromagnetic fields produced by a commercial light cure device, or mobile phone radiation (60 min), respectively. The fourth group was exposed to electromagnetic radiations emitted by both mobile phone for 60 min and light cure device. Then, teeth samples were scored for microleakage according to a standard dye penetration protocol by examination under a stereomicroscope.Results: The mean score of microleakage in the fourth group (light cure + mobile phone) was significantly higher than that of the control group (P =0.030). Moreover, the scores of microleakage in this group were significantly higher than that of the second group (light cure only) (P= 0.043).Conclusion: Exposure of amalgam restorations to electromagnetic fields produced by both light cure devices and mobile phones can synergistically increase the microleakage of amalgam restorations.

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