Vitamin-D deficiency is associated with chronic bacterial colonisation and disease severity in bronchiectasis.

PMID: 

Thorax. 2013 Jan ;68(1):39-47. Epub 2012 Oct 16. PMID: 23076388

Abstract Title: 

Vitamin-D deficiency is associated with chronic bacterial colonisation and disease severity in bronchiectasis.

Abstract: 

INTRODUCTION: Vitamin-D deficiency has been linked to an increased risk of respiratory infections. The objective of this study was to determine the frequency and clinical importance of vitamin-D deficiency in patients with bronchiectasis.METHODS: 25-hydroxyvitamin-D was measured by immunoassay in 402 stable patients with bronchiectasis. Patients were classified as vitamin-D deficient (serum 25-hydroxyvitamin-D

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Tobacco use increases susceptibility to bacterial infection

PMID: 

Tob Induc Dis. 2008 Dec 18 ;4:12. Epub 2008 Dec 18. PMID: 19094204

Abstract Title: 

Tobacco use increases susceptibility to bacterial infection.

Abstract: 

Active smokers and those exposed to secondhand smoke are at increased risk of bacterial infection. Tobacco smoke exposure increases susceptibility to respiratory tract infections, including tuberculosis, pneumonia and Legionnaires disease; bacterial vaginosis and sexually transmitted diseases, such as chlamydia and gonorrhoea; Helicobacter pylori infection; periodontitis; meningitis; otitis media; and post-surgical and nosocomial infections. Tobacco smoke compromises the anti-bacterial function of leukocytes, including neutrophils, monocytes, T cells and B cells, providing a mechanistic explanation for increased infection risk. Further epidemiological, clinical and mechanistic research into this important area is warranted.

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Infants with total 25(OH)D <20 ng/mL had increased risk of intensive care and longer hospital stay.

PMID: 

J Pediatr. 2018 12 ;203:416-422.e1. Epub 2018 Sep 20. PMID: 30243543

Abstract Title: 

Vitamin D Status at the Time of Hospitalization for Bronchiolitis and Its Association with Disease Severity.

Abstract: 

OBJECTIVE: To investigate the association between circulating 25-hydroxyvitamin D [25(OH)D] status at admission and disease severity among infants hospitalized for bronchiolitis and to determine whether the association differs by the form of 25(OH)D-total, bioavailable or free 25(OH)D.STUDY DESIGN: We conducted a 17-center prospective cohort study of 1016 US infants

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Weekly low-dose vitamin A supplementation in a region of subclinical deficiency protected underweight children from acute lower respiratory infection.

PMID: 

Pediatrics. 1999 Jul ;104(1):e1. PMID: 10390287

Abstract Title: 

The beneficial effects of weekly low-dose vitamin A supplementation on acute lower respiratory infections and diarrhea in Ecuadorian children.

Abstract: 

BACKGROUND: Previous studies of large-dose vitamin A supplementation on respiratory morbidity have produced conflicting results in a variety of populations. The influence of malnutrition has not been examined in the majority of these trials. We hypothesized that weekly low-dose vitamin A supplementation would prevent respiratory and diarrheal disease morbidity and that malnutrition might influence the efficacy of vitamin A supplementation.METHODS: In a randomized, double-blind, placebo-controlled field trial of 400 children, 6 to 36 months of age in a high Andean urban slum, half of the children received 10 000 IU of vitamin A weekly and half received placebo for 40 weeks. Children were visited weekly at home by physicians and assessed for acute diarrheal disease and acute respiratory infections.RESULTS: Acute diarrheal disease and acute respiratory infection did not differ globally or by severity between supplement-treated and placebo groups. However, the incidence of acute lower respiratory infection (ALRI) was significantly lower in underweight (weight-for-age z score [WAZ]-2 SD) supplement-treated children than in normal-weight children on placebo (9.8 vs 4.4 per 10(3) child-weeks; rate ratio: 2.21 [95% CI: 1.24-3.93]). By logistic regression analysis the risk of ALRI was lower in underweight supplement-treated children than in underweight children on placebo (point estimate 0.148 [95% CI: 0.034-0.634]). In contrast, risk of ALRI was higher in normal-weight supplement-treated children (WAZ>-1 SD to mean) than in normal-weight children on placebo in the same WAZ stratum (point estimate: 2.51 [95% CI: 1.24-5.05]). The risk of severe diarrhea was lower in supplement-treated children 18 to 23 months of age than in children on placebo in this age group (point estimate: 0.26 [95% CI: 0.06-1.00]).CONCLUSIONS: Weekly low-dose (10 000 IU) vitamin A supplementation in a region of subclinical deficiency protected underweight children from ALRI and paradoxically increased ALRI in normal children with body weight over -1 SD. Protection from severe diarrhea was consistent with previous trials. Additional research is warranted to delineate potential beneficial and detrimental interactions between nutritional status and vitamin A supplementation regarding ALRI.

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This study found that cupping effectively improved fever in 96.12% of individuals with upper respiratory infection.

PMID: 

J Tradit Chin Med. 2002 Jun ;22(2):124-5. PMID: 12125487

Abstract Title: 

Cupping therapy for 103 cases of high fever due to infection of the upper respiratory tract.

Abstract: 

[n/a]

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This paper outlines the benefits of cupping therapy for various conditions.

PMID: 

J Tradit Complement Med. 2015 Jul ;5(3):127-34. Epub 2015 Feb 10. PMID: 26151023

Abstract Title: 

Cupping therapy: A prudent remedy for a plethora of medical ailments.

Abstract: 

Since ancient times, complementary and alternative medicine (CAM; bǔ chōng yǔ tì dài yī xué) have played an important role in human health and welfare. Many therapeutic approaches in healthcare outside the realm of conventional medicine persist in various parts of the world. There is considerable scientific and commercial potential in CAM, which needs to beexplored precisely. Cupping therapy ( bá guàn liáo fǎ), one of the CAM, is practiced across the world. This therapy is believed to act by correcting imbalances in the internal bio field, such as by restoring the flow of"Qi (qì)". Cupping involves applying a heated cup to generate a partial vacuum that mobilizes the blood flow and promotes effective healing. This review outlines various tools and techniques of cupping therapy.

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Cupping has a promising role in helping manage dermatological conditions.

PMID: 

Acta Dermatovenerol Alp Pannonica Adriat. 2018 Jun ;27(2):103-107. PMID: 29945267

Abstract Title: 

Cupping in dermatology: a critical review and update.

Abstract: 

Cupping is an ancient procedure that has been practiced for thousands of years. It has been used to treat a variety of medical conditions, including dermatological ones. Cupping has been described in the literature for the treatment of conditions such as acne and eczema. The procedure is fundamentally divided into dry cupping and wet cupping; however, there have been many modern adaptations. Adverse events related to the procedure have been reported in the literature and should be considered by patients. However, cupping has a promising role in helping manage dermatological conditions.

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This study utilized cupping, blood-letting puncture, and Chinese-drug face mask to achieve a 75% cure rate in acne patients.

PMID: 

J Tradit Chin Med. 2005 Dec ;25(4):270-2. PMID: 16447668

Abstract Title: 

Thirty-two cases of acne treated with blood-letting puncture, cupping and Chinese-drug facemask.

Abstract: 

To observe the therapeutic effect on acne treated with blood-letting puncture, cupping and Chinese-drug facemask. Thirty-two patients with acne were treated with above-mentioned therapeutic method. Cure, improvement and ineffectiveness were respectively found in 24, 7 and 1 case, with a curative rate of 75.0% and a total effective rate of 96.8%. The combination of blood-letting puncture, cupping and external application of Chinese-drug facemask is effective in treating acne.

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