PMID: Am J Reprod Immunol. 2019 Sep 4:e13186. Epub 2019 Sep 4. PMID: 31483910 Abstract Title: Resveratrol Treatment in Patients with Polycystic Ovary Syndrome Decreased Pro-inflammatory and Endoplasmic Reticulum Stress Markers. Abstract: PROBLEM: Polycystic ovary syndrome (PCOS) is associated with endoplasmic reticulum (ER) stress and pro-inflammatory condition. The aim of the present study was to …
Category Archives: Uncategorized
Supplementation of resveratrol in patients with T2DM and coronary heart disease had beneficial effects on glycemic control, HDL-cholesterol levels.
PMID: Food Funct. 2019 Sep 5. Epub 2019 Sep 5. PMID: 31486447 Abstract Title: The effects of resveratrol on metabolic status in patients with type 2 diabetes mellitus and coronary heart disease. Abstract: This study was performed to investigate the effects of resveratrol on metabolic status in patients with type 2 diabetes mellitus (T2DM) and …
Carvacrol reduced tissue damage and bone loss caused by ligation-induced periodontitis.
PMID: J Periodontol. 2017 07 ;88(7):e120-e128. Epub 2017 Apr 7. PMID: 28387609 Abstract Title: Carvacrol Ameliorates Ligation-Induced Periodontitis in Rats. Abstract: BACKGROUND: This study aims to evaluate the ameliorative effect of carvacrol, an anti-inflammatory monoterpenoid phenol and a major component of Plectranthus amboinicus, on periodontal damage in an experimental rat model of periodontitis.METHODS: Forty Sprague-Dawley …
Carvacrol could potentially be used to control gut dysbiosis and reduce C. difficile infection.
PMID: Front Microbiol. 2017 ;8:625. Epub 2017 Apr 21. PMID: 28484429 Abstract Title: Protective Effect of Carvacrol against Gut Dysbiosis andAssociated Disease in a Mouse Model. Abstract: This study investigated the effect of carvacrol (CR), a phytophenolic compound on antibiotic-associated gut dysbiosis andinfection in a mouse model. Five to six-week-old C57BL/6 mice were randomly divided …
Carvacrol promotes neuroprotection in the mouse hemiparkinsonian model.
PMID: Neuroscience. 2017 07 25 ;356:176-181. Epub 2017 May 17. PMID: 28526576 Abstract Title: Carvacrol promotes neuroprotection in the mouse hemiparkinsonian model. Abstract: Carvacrol is a monoterpene that has been linked to neuroprotection in several animal models of neurodegeneration, including ischemia, epilepsy and traumatic neuronal injury. In this study, we investigated the effects of carvacrol …
Continue reading “Carvacrol promotes neuroprotection in the mouse hemiparkinsonian model.”
Carvacrol possesses strong ameliorative effects on sepsis.
PMID: Inflammation. 2017 Oct ;40(5):1654-1663. PMID: 28646428 Abstract Title: Effects of Carvacrol on Survival, Mesenteric Blood Flow, Aortic Function and Multiple Organ Injury in a Murine Model of Polymicrobial Sepsis. Abstract: Carvacrol (CRV) has strong cytoprotective, antioxidant, and anti-inflammatory properties. We aimed to demonstrate the possible protective effects of CRV on survival, mesenteric artery blood …
Continue reading “Carvacrol possesses strong ameliorative effects on sepsis.”
Carvacrol could be a promising chemotherapeutic agent for prostate cancer.
PMID: Nutr Cancer. 2017 Oct ;69(7):1075-1087. Epub 2017 Sep 5. PMID: 28872904 Abstract Title: Carvacrol Induces Reactive Oxygen Species (ROS)-mediated Apoptosis Along with Cell Cycle Arrest at G/Gin Human Prostate Cancer Cells. Abstract: Carvacrol, a major monoterpenoid phenol from Origanum and Thymus species, has been shown to exhibit antiproliferative and anticancer properties in a few …
Continue reading “Carvacrol could be a promising chemotherapeutic agent for prostate cancer.”
Ursolic acid induces apoptosis and inhibits invasion of GBC-SD gallbladder carcinoma cells.
PMID: Oncol Lett. 2019 Aug ;18(2):1467-1474. Epub 2019 May 27. PMID: 31423212 Abstract Title: Ursolic acid isolated frominduces apoptosis and inhibits invasion of GBC-SD gallbladder carcinoma cells. Abstract: Gallbladder carcinoma (GBC) is a relatively rare but terminal malignancy, and drug/chemical development is an important aspect of prevention and treatment of GBC. Ursolic acid (UA), a …
Carvacrol induced Ca²⁺-dissociated cell death in PC3 human prostate cancer cells.
PMID: Chin J Physiol. 2017 Oct 31 ;60(5):275-283. PMID: 28950692 Abstract Title: Effect of Carvacrol on Ca²⁺ Movement and Viability in PC3 Human Prostate Cancer Cells. Abstract: Carvacrol, a monoterpenic phenol compound, has been shown to possess various biological effects in different models. However, the effect of carvacrol on intracellular Ca²⁺ and its related physiology …
Continue reading “Carvacrol induced Ca²⁺-dissociated cell death in PC3 human prostate cancer cells.”
Ursolic acid and carvacrol may be potential inhibitors of dormancy protein small heat shock protein16.3 of Mycobacterium tuberculosis.
PMID: J Biomol Struct Dyn. 2018 Oct ;36(13):3434-3443. Epub 2017 Oct 20. PMID: 28984500 Abstract Title: Ursolic acid and carvacrol may be potential inhibitors of dormancy protein small heat shock protein16.3 of Mycobacterium tuberculosis. Abstract: Small heat shock protein16.3 (sHSP16.3) is a crucial protein for survival of Mycobacterium tuberculosis (MTB) in its host. Besides, this …
Health Time 