PMID: Biomed Pharmacother. 2017 Dec ;96:313-319. Epub 2017 Oct 7. PMID: 29017143 Abstract Title: Protective effect of carvacrol on acetic acid-induced colitis. Abstract: The pharmacological therapy for inflammatory bowel diseases continues to be problematic, and requires new alternative options. In this study, we tested the hypothesis that carvacrol (CAR), a phenolic monoterpene with anti-inflammatory and …
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PMID: Phytother Res. 2018 Jan ;32(1):151-159. Epub 2017 Nov 28. PMID: 29193478 Abstract Title: Possible therapeutic effect of carvacrol on asthmatic patients: A randomized, double blind, placebo-controlled, Phase II clinical trial. Abstract: The relaxant effects of carvacrol, a phenolic monoterpene, on tracheal smooth muscle and its preventive effect on asthmatic animals were reported. The effect …
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PMID: Mol Med Rep. 2018 Mar ;17(3):3987-3992. Epub 2017 Dec 19. PMID: 29257341 Abstract Title: Carvacrol ameliorates inflammatory response in interleukin 1β-stimulated human chondrocytes. Abstract: Carvacrol, a monoterpenic phenol present in Origanum vulgare (oregano) and Thymus vulgaris (thyme), possesses anti‑inflammatory effects; however, little is known about the effects and underlying mechanism of carvacrol on chondrocytes in osteoarthritis …
PMID: Anticancer Res. 2018 01 ;38(1):279-286. PMID: 29277784 Abstract Title: Carvacrol Targets AXL to Inhibit Cell Proliferation and Migration in Non-small Cell Lung Cancer Cells. Abstract: BACKGROUND/AIM: AXL has been reported to be overexpressed and highly activated in various cancer types. In this study, we demonstrated the effect of carvacrol on cell proliferation and migration …
PMID: Nutrients. 2018 Sep 14 ;10(9). Epub 2018 Sep 14. PMID: 30223488 Abstract Title: Bergamot Polyphenol Fraction Exerts Effects on Bone Biology by Activating ERK 1/2 and Wnt/β-Catenin Pathway and Regulating Bone Biomarkers in Bone Cell Cultures. Abstract: Epidemiological studies show that fruit consumption may modulate bone mineral density. However, data regarding the effect of …
PMID: J Biol Regul Homeost Agents. 2017 Oct-Dec;31(4):1087-1093. PMID: 29254319 Abstract Title: Lipid-lowering effect of bergamot polyphenolic fraction: role of pancreatic cholesterol ester hydrolase. Abstract: Bergamot polyphenolic fraction (BPF) has been shown to positively modulate several mechanisms involved in metabolic syndrome, suggesting its use in therapy. In particular, it is able to induce a significant …
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PMID: Endocr Metab Immune Disord Drug Targets. 2019 ;19(2):136-143. PMID: 30501605 Abstract Title: Hypoglycemic and Hypolipemic Effects of a New Lecithin Formulation of Bergamot Polyphenolic Fraction: A Double Blind, Randomized, Placebo- Controlled Study. Abstract: OBJECTIVE: Hyperlipemia represents an independent risk factor in the development of atherosclerosis in patients undergoing type 2 diabetes mellitus (DM). Moreover, …
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PMID: Front Pharmacol. 2018 ;9:1563. Epub 2019 Jan 17. PMID: 30705631 Abstract Title: Treatment With a Flavonoid-Rich Fraction of Bergamot Juice Improved Lipopolysaccharide-Induced Periodontitis in Rats. Abstract: In this study, we investigated the effects of a flavonoid-rich fraction of Bergamot juice (BJe) in rats subjected to experimental periodontitis induced by a single intragingival injection of …
PMID: Antioxidants (Basel). 2019 Mar 16 ;8(3). Epub 2019 Mar 16. PMID: 30884780 Abstract Title: Oxidative Imbalance and Kidney Damage in Cafeteria Diet-Induced Rat Model of Metabolic Syndrome: Effect of Bergamot Polyphenolic Fraction. Abstract: Obesity is a potent risk factor for kidney disease as it increases the possibility of developing diabetes and hypertension, and it …
PMID: Integr Food Nutr Metab. 2019 Mar ;6(2). Epub 2019 Feb 28. PMID: 31057945 Abstract Title: Clinical application of bergamot () for reducing high cholesterol and cardiovascular disease markers. Abstract: The bergamot is a citrus fruit native to southern Italy with traditional uses that include improving immune response and cardiovascular function. There are a variety …
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