Category Archives: Uncategorized

PMID:  Life Sci. 2019 Aug 27:116795. Epub 2019 Aug 27. PMID: 31470002 Abstract Title:  The neuroprotective effects of carvacrol on ischemia/reperfusion-induced hippocampal neuronal impairment by ferroptosis mitigation. Abstract:  OBJECTIVE: Cerebral ischemia is the most common type of neuronal injury and is characterized by a reduction in the function and number of hippocampal neurons. Carvacrol has …

Continue reading “Carvacrol provides protection for hippocampal neurons against cerebral ischemia.”

PMID:  Mol Nutr Food Res. 2019 03 ;63(6):e1800649. Epub 2019 Jan 3. PMID: 30575271 Abstract Title:  6-Gingerol Improves Ectopic Lipid Accumulation, Mitochondrial Dysfunction, and Insulin Resistance in Skeletal Muscle of Ageing Rats: Dual Stimulation of the AMPK/PGC-1α Signaling Pathway via Plasma Adiponectin and Muscular AdipoR1. Abstract:  SCOPE: This study investigates the dual actions of 6-gingerol …

Continue reading “6-Gingerol improves ectopic lipid accumulation, mitochondrial dysfunction, and insulin resistance in skeletal muscle of ageing rats.”

PMID:  Inflammopharmacology. 2019 Mar 2. Epub 2019 Mar 2. PMID: 30826930 Abstract Title:  Anti-inflammatory and renal protective effect of gingerol in high-fat diet/streptozotocin-induced diabetic rats via inflammatory mechanism. Abstract:  P38 mitogen-activated protein kinase (p38 MAPK), a tissue inflammatory factor can be activated under oxidative stress and in conditions associated with hyperglycemia. Gingerol containing various natural …

Continue reading “Anti-inflammatory and renal protective effect of gingerol in high-fat diet/streptozotocin-induced diabetic rats via inflammatory mechanism.”

PMID:  J Nat Med. 2019 Sep ;73(4):745-760. Epub 2019 Jun 8. PMID: 31177355 Abstract Title:  Suppression of colorectal cancer cell growth by combined treatment of 6-gingerol andγ-tocotrienol via alteration of multiple signalling pathways. Abstract:  Our previous study reported that combined treatment ofγ-tocotrienol with 6-gingerol showed promising anticancer effects by synergistically inhibiting proliferation of human colorectal …

Continue reading “Suppression of colorectal cancer cell growth by combined treatment of 6-gingerol and γ-tocotrienol.”

PMID:  Artif Cells Nanomed Biotechnol. 2019 Dec ;47(1):2016-2023. PMID: 31223035 Abstract Title:  6-Gingerol protects cardiocytes H9c2 against hypoxia-induced injury by suppressing BNIP3 expression. Abstract:  Cardiomyocytes loss is the predominant pathogenic characteristic in the hypoxia-induced injury. Meanwhile, it has been corroborated that Bcl-2 E1B 19-KDa interacting protein 3 (BNIP3) provokes apoptosis and autophagy. For moderating cardiomyocytes …

Continue reading “6-Gingerol protects cardiocytes H9c2 against hypoxia-induced injury by suppressing BNIP3 expression.”

PMID:  Mol Nutr Food Res. 2019 Jul 17:e1801356. Epub 2019 Jul 17. PMID: 31313461 Abstract Title:  Treatment with 6-Gingerol Regulates Dendritic Cell Activity and Ameliorates the Severity of Experimental Autoimmune Encephalomyelitis. Abstract:  SCOPE: Multiple sclerosis (MS) is an inflammatory demyelinating autoimmune disorder, with increasing incidence worldwide but unknown etiology. 6-Gingerol (6-GIN), a major dietary compound …

Continue reading “6-gingerol has significant potential as a novel anti-inflammatory agent for the treatment of autoimmune diseases such as multiple sclerosis.”

PMID:  Curr Aging Sci. 2019 Aug 8. Epub 2019 Aug 8. PMID: 31418667 Abstract Title:  Nigella sativa L., supplementary plant with anticholinesterase effect for cognition problems: A kinetic study. Abstract:  BACKGROUND: The average of lifespan and the aging population are rising worldwide. So neurodegenerative disease (ND) will be one of the most challenges associated with …

Continue reading “N. sativa is a good candidate for seeking the new anticholinesterase agent and could be considered as a good supplement for the health of the elderly.”

PMID:  Curr Pharm Biotechnol. 2019 Aug 21. Epub 2019 Aug 21. PMID: 31433749 Abstract Title:  In-Vitro Anti-Proliferative, Apoptotic And Antioxidative Activities Of Medicinal Herb Kalonji (Nigella sativa). Abstract:  BACKGROUND: Natural product with apoptotic activity could serve as potential new sources for anti-cancer medicine. Numerous phytochemicals from plants have shown to exert antineoplastic effects via programmed …

Continue reading “It was observed that Kalonji extracts have ability to induce apoptosis and improve the antioxidant status of HeLa and HepG2 cells.”

PMID:  Molecules. 2019 Aug 15 ;24(16). Epub 2019 Aug 15. PMID: 31443189 Abstract Title:  Alpha-Hederin, the Active Saponin of, as an Anticancer Agent Inducing Apoptosis in the SKOV-3 Cell Line. Abstract:  Alpha-hederin (α-HN), a pentacyclic triterpene saponin, has recently been identified as one of the active compounds of, as a potential anticancer agent. However, no …

Continue reading “Alpha-Hederin as an anticancer agent inducing apoptosis in the SKOV-3 cell line.”

PMID:  Antioxidants (Basel). 2019 Aug 25 ;8(9). Epub 2019 Aug 25. PMID: 31450670 Abstract Title:  Anti-Inflammatory, Anti-Arthritic and Anti-Nociceptive Activities ofOil in a Rat Model of Arthritis. Abstract:  This study investigated the preventive efficacy of the crude oil extracted fromseeds in a rat model of arthritis induced by using complete Freund's adjuvant (CFA).oil at 1.82 …

Continue reading “Nigella sativa oil significantly attenuated adjuvant-arthritis, and the higher dose prevented the development of arthritis with an inhibition of 56%.”