Angelica sinensis may be a potential anticancer agent by attenuating cancer angiogenesis.

PMID:  Sci Rep. 2017 07 14 ;7(1):5376. Epub 2017 Jul 14. PMID: 28710377 Abstract Title:  Antiangiogenic activity of phthalides-enriched Angelica Sinensis extract by suppressing WSB-1/pVHL/HIF-1α/VEGF signaling in bladder cancer. Abstract:  The hypoxia-inducible factor-1α (HIF-1α) plays a critical role in tumor angiogenesis. It has been reported that the acetone extract of Angelica sinensis (AE-AS) rich in …

These findings suggested that the cancer-preventive effect of Angelica sinensis root extract may be stage-dependent in the process of carcinogenesis.

PMID:  Int J Mol Sci. 2017 Aug 11 ;18(8). Epub 2017 Aug 11. PMID: 28800083 Abstract Title:  Effect of Angelica sinensis Root Extract on Cancer Prevention in Different Stages of an AOM/DSS Mouse Model. Abstract:  root (ASR) extract was obtained to investigate its effects on colorectal carcinogenesis in different stages of an Azoxymethane/Dextran sodium sulphate …

Angelica polysaccharides inhibit the growth and promote the apoptosis of U251 glioma cells in vitro and in vivo.

PMID:  Phytomedicine. 2017 Sep 15 ;33:21-27. Epub 2017 Jul 8. PMID: 28887916 Abstract Title:  Angelica polysaccharides inhibit the growth and promote the apoptosis of U251 glioma cells in vitro and in vivo. Abstract:  BACKGROUND: Angelica sinensis (Oliv) Diels (Apiaceae) is a traditional medicine that has been used for more than 2000 years in China. It …

Angelica sinensis suppresses body weight gain and alters expression of the FTO Gene in high-fat-diet induced obesity.

PMID:  Biomed Res Int. 2017 ;2017:6280972. Epub 2017 Sep 20. PMID: 29098158 Abstract Title:  Suppresses Body Weight Gain and Alters Expression of theGene in High-Fat-Diet Induced Obese Mice. Abstract:  The root of(RAS) is a traditional Chinese medicine used for preventing and treating various diseases. In this study, we assessed RAS supplementation effects on body weight …

Angelica sinensis exerts angiogenic and anti-apoptotic effects against cerebral ischemia-reperfusion injury.

PMID:  Am J Chin Med. 2017 ;45(8):1683-1708. Epub 2017 Nov 9. PMID: 29121798 Abstract Title:  Angelica sinensis Exerts Angiogenic and Anti-apoptotic Effects Against Cerebral Ischemia-Reperfusion Injury by Activating p38MAPK/HIF-1[Formula: see text]/VEGF-A Signaling in Rats. Abstract:  This study evaluated the effects of Angelica sinensis extract [Dang Gui (DG)] administered before 60[Formula: see text]min of middle cerebral …

Angelica sinensis polysaccharide could protect bone marrow stromal cells from chemotherapeutic injury.

PMID:  Int J Mol Sci. 2017 Oct 28 ;18(11). Epub 2017 Oct 28. PMID: 29143796 Abstract Title:  Angelica sinensis Polysaccharides Ameliorate Stress-Induced Premature Senescence of Hematopoietic Cell via Protecting Bone Marrow Stromal Cells from Oxidative Injuries Caused by 5-Fluorouracil. Abstract:  Myelosuppression is the most common complication of chemotherapy. Decline of self-renewal capacity and stress-induced premature …

Hygiene measures may reduce the risk of infection by greater than 20%. This study also provides evidence that death from infectious disease was on the decline prior to the introduction of vaccines.

PMID:  Lancet Infect Dis. 2002 Feb ;2(2):103-10. PMID: 11901641 Abstract Title:  What is the evidence for a causal link between hygiene and infections? Abstract:  Even in an era in which access to personal"cleanliness"and a public health infrastructure are readily available in developed countries, illnesses associated with day care centres and homes continue to be a …

Of 195,270 women who received HPV vaccine, 958 were hospitalized and 19,351 had an emergency department visit within 42 days of immunization.

n/a PMID:  Vaccine. 2016 Apr 4 ;34(15):1800-5. Epub 2016 Feb 26. PMID: 26921782 Abstract Title:  Adverse events following HPV vaccination, Alberta 2006-2014. Abstract:  BACKGROUND: In Canada, private purchase of human papilloma virus (HPV) vaccines has been possible since 2006. In Alberta, Canada, a publicly funded quadrivalent HPV vaccine program began in the 2008/2009 school year. …

Angelica sinensis polysaccharide protects against acetaminophen-induced acute liver injury

PMID:  Int J Biol Macromol. 2018 May ;111:1133-1139. Epub 2018 Feb 19. PMID: 29415408 Abstract Title:  Angelica sinensis polysaccharide protects against acetaminophen-induced acute liver injury and cell death by suppressing oxidative stress and hepatic apoptosis in vivo and in vitro. Abstract:  Acetaminophen (APAP)-induced hepatic damage is prevalent in western countries. The present study aimed to …

Oxidative stress in osteoarthritis and antioxidant effect of polysaccharide from angelica sinensis.

PMID:  Int J Biol Macromol. 2018 Aug ;115:281-286. Epub 2018 Apr 16. PMID: 29673954 Abstract Title:  Oxidative stress in osteoarthritis and antioxidant effect of polysaccharide from angelica sinensis. Abstract:  This study aimed to investigate the oxidative stress in human osteoarthritis (OA) chondrocytes and the antioxidant effect of angelica sinensis polysaccharide (ASP) on it. Human OA …

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