The most frequently reported adverse event in pregnant women who received the Tdap vaccine was spontaneous abortion.

PMID:  Am J Obstet Gynecol. 2012 Jul ;207(1):59.e1-7. Epub 2012 May 14. PMID: 22727350 Abstract Title:  Adverse event reports after tetanus toxoid, reduced diphtheria toxoid, and acellular pertussis vaccines in pregnant women. Abstract:  OBJECTIVE: We sought to characterize reports to the Vaccine Adverse Event Reporting System (VAERS) of pregnant women who received tetanus toxoid, reduced …

Polysaccharide from Angelica sinensis protects H9c2 cells against oxidative injury and endoplasmic reticulum stress.

PMID:  J Int Med Res. 2018 May ;46(5):1717-1733. Epub 2018 Mar 8. PMID: 29517941 Abstract Title:  Polysaccharide from Angelica sinensis protects H9c2 cells against oxidative injury and endoplasmic reticulum stress by activating the ATF6 pathway. Abstract:  Objectives Angelica sinensis exerts various pharmacological effects, such as antioxidant and anti-apoptotic activity. This study aimed to investigate the …

Angelica sinensis polysaccharide inhibits proliferation, migration, and invasion in human neuroblastoma cell line SH-SY5Y.

PMID:  Cell Biol Int. 2018 Jul ;42(7):867-876. Epub 2018 Mar 24. PMID: 29465760 Abstract Title:  Angelica sinensis polysaccharide inhibits proliferation, migration, and invasion by downregulating microRNA-675 in human neuroblastoma cell line SH-SY5Y. Abstract:  Neuroblastoma is the most common tumor diagnosed in children and infants, with high recurrence and poor prognosis. Angelica sinensis polysaccharide (AP) whose …

Angelica sinensis polysaccharide decreases hepcidin expression, which can reduce iron burden and inhibit tumor proliferation.

PMID:  Cell Physiol Biochem. 2018 ;47(3):1084-1094. Epub 2018 May 25. PMID: 29843136 Abstract Title:  The Effects of Angelica Sinensis Polysaccharide on Tumor Growth and Iron Metabolism by Regulating Hepcidin in Tumor-Bearing Mice. Abstract:  BACKGROUND/AIMS: Iron plays a fundamental role in cell biology and its concentration must be precisely regulated. It is well documented that excess …

Baboons vaccinated with acellular pertussis were protected from severe pertussis-associated symptoms but not from colonization, did not clear the infection faster than naïve animals, and readily transmitted B. pertussis to unvaccinated contacts.

PMID:  Proc Natl Acad Sci U S A. 2014 Jan 14 ;111(2):787-92. Epub 2013 Nov 25. PMID: 24277828 Abstract Title:  Acellular pertussis vaccines protect against disease but fail to prevent infection and transmission in a nonhuman primate model. Abstract:  Pertussis is a highly contagious respiratory illness caused by the bacterial pathogen Bordetella pertussis. Pertussis rates …

Anti-inflammatory effects of Angelica sinensis water extract on RAW 264.7 induced with lipopolysaccharide.

PMID:  Nutrients. 2018 May 21 ;10(5). Epub 2018 May 21. PMID: 29883374 Abstract Title:  Anti-Inflammatory Effects of(Oliv.) Diels Water Extract on RAW 264.7 Induced with Lipopolysaccharide. Abstract:  The dry root of(Oliv.) Diels, also known as“female ginseng”, is a popular herbal drug amongst women, used to treat a variety of health issues and cardiovascular diseases. The …

Phthalide dimers from Angelica sinensis and their COX-2 inhibition activity.

PMID:  Fitoterapia. 2018 Sep ;129:102-107. Epub 2018 Jun 21. PMID: 29935258 Abstract Title:  Phthalide dimers from Angelica sinensis and their COX-2 inhibition activity. Abstract:  Four new dimeric phthalides, angesinenolides C-F (1-4), along with three known ones, were isolated from the roots of Angelica sinensis. Their structures were determined by means of HRMS and NMR experiments. …

This detailed review indicates that smallpox is not quite as contagious or virulent as it has been made out to be. Most transmission from smallpox-infected patients occurs in hospitals from infected linens and cannot be transmitted via the exhaled air.

PMID:  N Engl J Med. 2003 Jan 30 ;348(5):460-3. Epub 2002 Dec 19. PMID: 12496354 Abstract Title:  A different view of smallpox and vaccination. Abstract:  [No Abstract Available] read more

Angelica sinensis polysaccharide protects rat cardiomyocytes H9c2 from hypoxia-induced injury by down-regulation of microRNA-22.

PMID:  Biomed Pharmacother. 2018 Oct ;106:225-231. Epub 2018 Jun 28. PMID: 29960169 Abstract Title:  Angelica sinensis polysaccharide protects rat cardiomyocytes H9c2 from hypoxia-induced injury by down-regulation of microRNA-22. Abstract:  BACKGROUND: The cardioprotective role of Angelica sinensis has been proven in previous studies. However, the effects of Angelica sinensis polysaccharide (ASP, major bioactive component of Angelica …

Angelica sinensis pretreatment could effectively guard the liver and kidney of mice from D-galactose-induced injury.

PMID:  J Med Food. 2018 Sep ;21(9):887-898. Epub 2018 Aug 15. PMID: 30109956 Abstract Title:  Angelica sinensis Supercritical Fluid COExtract Attenuates D-Galactose-Induced Liver and Kidney Impairment in Mice by Suppressing Oxidative Stress and Inflammation. Abstract:  Angelica sinensis (AS, Danggui in Chinese) is an important herbal component of various traditional formulae for the management of asthenia …

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