PMID: Biomed Pharmacother. 2018 Aug ;104:798-805. Epub 2018 May 29. PMID: 29852354 Abstract Title: Anti-proliferative benefit of curcumol on human bladder cancer cells via inactivating EZH2 effector. Abstract: We investigated the molecular mechanism of curcumol-induced apoptosis in bladder cancer cells. The mitochondrial membrane potential was measured using JC-1 staining. ROS generation of bladder cancer cells …
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Curcumol induces cell cycle arrest and apoptosis in human nasopharyngeal carcinoma CNE-2 cells.
PMID: Phytother Res. 2018 Nov ;32(11):2214-2225. Epub 2018 Aug 2. PMID: 30069933 Abstract Title: Curcumol induces cell cycle arrest and apoptosis by inhibiting IGF-1R/PI3K/Akt signaling pathway in human nasopharyngeal carcinoma CNE-2 cells. Abstract: Curcumol has been proved to possess antitumor effects in vivo and in vitro in several cancers. Previously, we have found that curcumol …
Curcumol induces RIPK1/RIPK3 complex-dependent necroptosis via JNK1/2-ROS signaling in hepatic stellate cells.
PMID: Redox Biol. 2018 10 ;19:375-387. Epub 2018 Sep 7. PMID: 30237126 Abstract Title: Curcumol induces RIPK1/RIPK3 complex-dependent necroptosis via JNK1/2-ROS signaling in hepatic stellate cells. Abstract: It is generally recognized that hepatic fibrogenesis is an end result of increased extracellular matrix (ECM) production from the activation and proliferation of hepatic stellate cells (HSCs). An …
This research demonstrated that curcumol reduced the proliferation of colorectal cancer cells.
PMID: Life Sci. 2019 Mar 15 ;221:354-361. Epub 2019 Feb 24. PMID: 30811964 Abstract Title: Curcumol inhibits colorectal cancer proliferation by targeting miR-21 and modulated PTEN/PI3K/Akt pathways. Abstract: AIMS: The purpose of this study was to demonstrate how curcumol affected the expression of miR-21 and whether its effects on miR-21 was associated with the activation …
Curcumol and curcumin showed an anti-inflammatory effect by inhibiting the NF-κB signaling pathway.
PMID: Evid Based Complement Alternat Med. 2019 ;2019:3035125. Epub 2019 Mar 17. PMID: 31007701 Abstract Title: Curcumin and Curcumol Inhibit NF-B and TGF-/Smads Signaling Pathways in CSE-Treated RAW246.7 Cells. Abstract: E-Zhu () is known as a classical traditional Chinese medicine and widely used in the treatment of cancers, cardiovascular disease, inflammation, and other diseases. Its …
The reported data reveals multitarget activity of curcumol in cancer treatment.
PMID: Int J Biol Sci. 2019 ;15(8):1600-1609. Epub 2019 Jun 4. PMID: 31360103 Abstract Title: Curcumol: From Plant Roots to Cancer Roots. Abstract: Natural products, an infinite treasure of bioactive scaffolds, have provided an excellent reservoir for the discovery of drugs since millennium. These naturally occurring, biologically active and therapeutically effective chemical entities have emerged …
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Curcumin as a permeability enhancer enhanced the antihyperlipidemic activity of dietary green tea extract.
PMID: BMC Complement Altern Med. 2019 Jun 13 ;19(1):129. Epub 2019 Jun 13. PMID: 31196040 Abstract Title: Curcumin as a permeability enhancer enhanced the antihyperlipidemic activity of dietary green tea extract. Abstract: BACKGROUND: Green tea has polyphenols like flavonoids and catechins; mainly epigallocatechin-3-gallate (EGCG), epicatechin gallate (ECG), epigallocatechin (EGC) and epicatechin (EC), out of which …
Tualang honey ameliorates viral load, CD4 counts and improves quality of life in asymptomatic human immunodeficiency virus infected patients.
PMID: J Tradit Complement Med. 2019 Oct ;9(4):249-256. Epub 2018 Sep 28. PMID: 31453119 Abstract Title: Tualang honey ameliorates viral load, CD4 counts and improves quality of life in asymptomatic human immunodeficiency virus infected patients. Abstract: This is the first study to report on the effects of honey in asymptomatic HIV positive subjects in ameliorating …
Consumption of oral royal jelly for eight weeks was effective in alleviating the menopausal symptoms.
PMID: Complement Ther Clin Pract. 2019 Aug 22 ;37:47-50. Epub 2019 Aug 22. PMID: 31470366 Abstract Title: Effect of royal jelly on menopausal symptoms: A randomized placebo-controlled clinical trial. Abstract: BACKGROUND: and Purpose: Menopause is associated with physical and emotional discomfort for women and has major negative effects on their quality of life. The purpose …
T. officinale leaf extract possesses significant anti-oxidant effects.
PMID: Antioxidants (Basel). 2019 Aug 15 ;8(8). Epub 2019 Aug 15. PMID: 31443195 Abstract Title: In Vitro and In Vivo Antioxidant Properties ofinω-Nitro-l-Arginine Methyl Ester (L-NAME)-Induced Hypertensive Rats. Abstract: Oxidative stress has gained attention as one of the fundamental mechanisms responsible for the development of hypertension. The present study investigated in vitro and in vivo …
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