Carthamus tinctorius may be used as an alternative therapeutic agent while treating patients with anxiety and depressive disorders.

PMID:  Pak J Pharm Sci. 2015 May ;28(3):991-5. PMID: 26004733 Abstract Title:  Short communication-Evaluation of antianxiety and antidepressant properties of Carthamus tinctorius L. (Safflower) petal extract. Abstract:  Nowadays anxiety and depression are most commonly encountered diseases. They are not only difficult to diagnose but even difficult to treat since both are sometimes seen together or …

Protective effect of Salvia miltiorrhiza and Carthamus tinctorius extract against lipopolysaccharide-induced liver injury.

PMID:  World J Gastroenterol. 2015 Aug 14 ;21(30):9079-92. PMID: 26290634 Abstract Title:  Protective effect of Salvia miltiorrhiza and Carthamus tinctorius extract against lipopolysaccharide-induced liver injury. Abstract:  AIM: To investigate the hepatoprotective effects and mechanisms of an extract of Salvia miltiorrhiza and Carthamus tinctorius in vivo.METHODS: C57BL/6J mice were randomly assigned to five groups and intraperitoneally …

Ginsenoside Rh2 exerts anti-metastasis activity in hypoxic tumor microenvironment in lung adenocarcinoma cells via mir-491.

PMID:  Anticancer Agents Med Chem. 2019 Jul 4. Epub 2019 Jul 4. PMID: 31272362 Abstract Title:  Ginsenoside Rh2 Inhibits Migration of Lung Cancer Cells Under Hypoxia via mir-491. Abstract:  BACKGROUND: Ginsenoside Rh2 (Rh2), which is extracted form ginseng, exerts antitumor activity. Here we would like to study the role of Rh2 on hypoxia-induced migration in …

This data clarifies the potential therapeutic significance of ginsenoside Rg1 for neuroprotective intervention strategies of diabetic retinopathy.

PMID:  J Agric Food Chem. 2019 Jul 31 ;67(30):8348-8360. Epub 2019 Jul 19. PMID: 31304751 Abstract Title:  Neuroprotective Effects of Ginsenoside Rg1 against Hyperphosphorylated Tau-Induced Diabetic Retinal Neurodegeneration via Activation of IRS-1/Akt/GSK3β Signaling. Abstract:  We have recently demonstrated that tau hyperphosphorylation causes diabetic synaptic neurodegeneration of retinal ganglion cells (RGCs), which might be the earliest …

Ginsenoside Rb1 inhibits proliferation and promotes apoptosis by regulating HMGB1 in uterine fibroid cells.

PMID:  Artif Cells Nanomed Biotechnol. 2019 Dec ;47(1):2967-2971. PMID: 31313594 Abstract Title:  Ginsenoside Rb1 inhibits proliferation and promotes apoptosis by regulating HMGB1 in uterine fibroid cells. Abstract:  To study the effects of ginsenoside Rb1 and the molecular mechanisms on proliferation and apoptosis of uterine fibroid cells, Rb1 + pc DNA3.1, Rb1 + pc DNA3.1-HMGB1, si-NC or si-HMGB1 was transfected …

Ginsenoside compound K inhibits nuclear factor-kappa B by targeting Annexin A2.

PMID:  J Ginseng Res. 2019 Jul ;43(3):452-459. Epub 2018 Apr 21. PMID: 31308817 Abstract Title:  Ginsenoside compound K inhibits nuclear factor-kappa B by targeting Annexin A2. Abstract:  Background: Ginsenoside compound K(C-K), a major metabolite of ginsenoside, exhibits anticancer activity in various cancer cells and animal models. A cell signaling study has shown that C-K inhibited …

Ginsenoside Rb1 may serve as a potential candidate for the treatment of Parkinson’s disease.

PMID:  Aging (Albany NY). 2019 Jul 17 ;11(14):5008-5034. PMID: 31314744 Abstract Title:  Ginsenoside Rb1 regulates prefrontal cortical GABAergic transmission in MPTP-treated mice. Abstract:  Parkinson's disease (PD) is a common neurodegenerative disease, featured by motor deficits and non-motor symptoms such as cognitive impairment, and malfunction of gamma-aminobutyric acid (GABA) mediated inhibitory transmission plays an important role …

Ginsenoside Rb1 inhibits vascular calcification as a selective androgen receptor modulator.

PMID:  Eur J Pharmacol. 2019 Sep 15 ;859:172546. Epub 2019 Jul 15. PMID: 31319068 Abstract Title:  Ginsenoside Rb1 inhibits vascular calcification as a selective androgen receptor modulator. Abstract:  Ginsenoside Rb1 (Rb1), a major component of ginseng, has a steroidal chemical structure, implying that it exerts sex hormone-like actions. Recent studies have been suggested cardioprotective actions …

Ginsenoside Re could be a potential therapeutic approach for the treatment of Alzheimer’s disease.

PMID:  Molecules. 2019 Jul 24 ;24(15). Epub 2019 Jul 24. PMID: 31344860 Abstract Title:  Ginsenoside Re Inhibits ROS/ASK-1 Dependent Mitochondrial Apoptosis Pathway and Activation of Nrf2-Antioxidant Response in Beta-Amyloid-Challenged SH-SY5Y Cells. Abstract:  Accumulation of amyloid-β (Aβ), which results in the formation of senile plaques that cause oxidative damage and neuronal cell death, has been accepted …

[Video] CBD oil, made from cannabis, is popular for calming anxiety

https://www.bbc.com/news/av/stories-49286389/cbd-oil-made-from-cannabis-is-popular-for-calming-anxiety Natalie, who has bought a bottle of Cannabidiol (CBD) oil online, has a few questions she wants answering before she decides whether to take it. On this journey, Natalie meets a hemp farmer, a scientist, and tests the product at a laboratory. CBD products, which are made from a cannabis extract, are very popular …

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